Alderley Park. World-class science in a world-class setting

Transcription

1 Alderley Park World-class science in a world-class setting

2 With our partners and the community of exceptional scientists who choose to remain at Alderley Park, we will build a flagship for a vibrant life sciences industry in the North of England. Chris Oglesby MSP Chairman and Bruntwood CEO P.2

3 Contents Introducing Alderley Park 4 A world-class setting for world-class science 6 At the heart of a scientific ecosystem 8 A clear vision for the future 10 Mereside 12 The Radnor Atrium 13 Alderley Park laboratory space 14 Laboratory areas and facilities 16 The BioHub Incubator 20 Parklands 21 Our first major redevelopment 22 The conference centre 24 A well-connected location 26 A great place to live and work 28 A historic, natural setting for health and wellbeing 30 P.3

4 Introducing Alderley Park Alderley Park represents a once-in-a-generation opportunity for the UK life science sector. Until March 2014, Alderley Park was the global R&D HQ for AstraZeneca, with a long and distinguished track record for drug discovery and development. As AstraZeneca prepare to relocate most of their operations, they leave two remarkable legacies and a huge opportunity. The first is an exceptional talent pool of science professionals who have elected to remain in our region, and who want to continue their work at Alderley Park. The second is an extraordinarily well-invested campus of beautiful buildings, superbly equipped for full spectrum bioscience, located in a tranquil lakeside setting. Alderley Park is a major asset within the UK s life science industry, with an international reputation. As owners of the site, Manchester Science Partnerships (MSP) intention is to maintain and strengthen this position, working with health science partners across the North of England and beyond, and most importantly with the business community. Our goal is to create within this remarkable site, a collaborative community of bioscience innovators and businesses at every stage of growth, with access to superb specialist equipment and a full range of support services in an open innovation campus environment. As part of the Bruntwood Group, it is our way to be outward facing and to play a full part in the wider life of the communities we serve. At Alderley Park we will fulfil our vision by working with our commercial, academic and clinical partners, and with national policy makers to ensure that the work which is done here is of global quality and impact. Alderley Park is uniquely placed to drive the future growth of this critically important sector for the economy and society. We are confident that with our partners we will realise that opportunity in full. Rowena Burns Chief Executive Manchester Science Partnerships The Radnor reception P.4

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6 A world-class setting for world-class science With over 1.5m sq ft of premier scientific, laboratory, office and conferencing space, Alderley Park is the leading life science facility in the North of England and the largest R&D campus of its kind in the UK. Set within 400 acres of beautiful Cheshire parkland, the campus has been an internationally important scientific location for over 50 years, with a rich heritage in pharmaceutical R&D and drug development. It has been home to the development of 12 new drugs, and groundbreaking discoveries such as beta blockers through the work of Nobel prize-winning physician and pharmacologist, Sir James Black, and more recently a number of targeted therapies in oncology. Millions of patients have benefited from innovations developed at Alderley Park and it is the most commercially successful drug development site of its kind in the world. With over 550m invested by AstraZeneca in world-class facilities and infrastructure over the past decade, Alderley Park is one of the bestinvested bioscience R&D sites in Europe. Its nationally-significant assets include not only highly-specialised labs, offices and equipment, but also some of the worlds most skilled and experienced science professionals. With its environment, energy and power infrastructure all purposely-designed for a specialist Life Science facility, Alderley Park is unique both in its quality and scale. Alderley Park is centrally located in the UK and is very well connected for such an idyllic parkland setting, boasting exceptional transport links. Located just five miles from Manchester Airport and 12 miles from Manchester city centre, it is at the heart of the North West motorway network, providing easy access by car across the whole of the UK. With two mainline rail stations within 20 minutes of the site, London is less than two hours away by train. What Alderley Park offers: Important scientific assets High-specification office space Industry-leading laboratory space An international conference centre, restaurants and cafés Gym and indoor and outdoor sports facilities 200 acres of private parkland Living and hotel accommodation close by, with future on-site accommodation planned P.6

7 Size (acres) of the Alderley Park estate Million lettable sq ft under MSP development plans Million pounds invested in the site over the last decade Years established as UK centre of R&D excellence P.7

8 At the heart of a scientific ecosystem Alderley Park is at the centre of a growing scientific ecosystem in the North of England and is the primary focus for the regions bioscience business cluster, driving the development of the next generation of life science companies through collaboration with academic and clinical partners. With Manchester just twenty minutes away, the vast wealth of the city s assets, activity and reputation as a hotspot of scientific discovery and innovation provides significant opportunities for companies and R&D centres located at the Park. MSP s Corridor sites are home to significant clusters across digital, medtech, healthcare technologies, advanced materials and manufacturing. Manchester s universities offer multiple opportunities to connect with world-leading academics and research centres in specialist areas including e-health, oncology and genetics. Thirty five miles in the opposite direction lies the port city of Liverpool, boasting the UK s largest concentration of biopharmaceutical manufacturing facilities in the UK. In Macclesfield, just a few miles from Alderley Park, is AstraZeneca s second largest manufacturing and late-stage R&D site in the UK, which employs 2,000 staff from where pharmaceutical products are shipped globally on a daily basis. Throughout the region, MSP has close links with the leading NHS trusts and research intensive universities through the Northern Health Science Alliance and with other business clusters and innovation communities through the North West Innovation Network. MSP is the largest science park operator in the UK with a 30 year track record in catalysing the growth of science and technology businesses. Through a trusted network of scientists, innovators, entrepreneurs and investors, MSP provides the right connections for innovation to flourish and concepts to become commercial reality. MSP s partnership structure is at the heart of its culture and approach to creating the right places and conditions for science and technology businesses to thrive. By locating at Alderley Park, businesses can take advantage of these established networks, scientific talent and pipeline of innovation that runs from academia through clinical research to commercial development and business success. P.8

9 Access is available to regional 42m Life Science Investment Funds The University of Manchester has the largest number of international students in the UK There are 152,000 engineering and science students within a one hour drive The Manchester Academic Health Science Centre includes Europe s largest cancer research and delivery centre and Europe s largest childrens hospital The region has one of the highest recruiting NIHR Clinical Research Networks The Northern Health Science Alliance covers a 15m patient population P.9

10 A clear vision for the future MSP s goal at Alderley Park is to create a vibrant and diverse bioscience community in an open innovation environment that will become a flagship location for life science sector growth. As Alderley Park s new owners, MSP is developing a long-term masterplan that aims to create a dynamic community of R&D centres and science and technology companies working in an environment designed to encourage collaboration and the sharing of risk and reward that is essential for the delivery of future investment and business success. Significant investment and an extensive transformation programme will see MSP redevelop and expand the site into a globally leading campus for the next generation of life science businesses. This will include adapting the site s R&D facilities to facilitate the growth of a community of life science businesses that can specialise in different aspects of the drug discovery chain. MSP will also develop additional commercial, retail, leisure and accommodation opportunities to enhance the amenity of the site for both the life science community and the local area. What the future offers: A collaborative and connected commercial community of people Approximately 1.5m+ sq ft of scientific and commercial space Long-term capital investment programme with 30m for the first phase to 2018 Access to 42m Life Science Investment Fund A bioscience incubator to help develop new and innovative businesses A high quality events and conference programme Top-end sports and recreational amenities A beautiful physical environment Potential on-site accommodation and appropriate retail facilities Following the acquisition of Alderley Park by MSP, AstraZeneca is gradually decanting its R&D activity to a new site in an agreed programme to Some areas of the site are immediately available for new occupiers, with other individual buildings and facilities gradually transferring to MSP on AstraZeneca s departure. As the business departs, it will leave behind a range of top quality, specialist scientific facilities as well as a range of well-appointed and highly desirable research and office spaces. The following pages give an overview of the buildings and facilities available and their potential for future development. P.10

11 Site boundary PDL boundary Open space Woodland Life sciences park Residential Mixed uses Existing buildings retained Existing vehicular links Existing tracks Potential public access route Green links Central street Potential sports provision P.11

12 Mereside The Mereside Research Complex forms the physical heart of Alderley Park s bioscience campus and is located next to Radnor Mere. The complex itself provides a worldclass scientific environment for the continued search for new medicines, consisting of superb chemistry and biological facilities, a world-class preclinical imaging suite, NMR suite, biobank, vivarium, compound bank, and the BioHub incubator housing a growing community of biotech SMEs. In addition, the complex boasts modern offices, a stunning glass atrium, a hightech conference centre, restaurant and car parking for approximately Two key scientific components of the complex are Buildings 33 and 35, which provide industry-leading facilities for chemistry, bioscience, drug metabolism, mass spectroscopy and nuclear magnetic resonance. The laboratories, write-up areas and other spaces have been designed to the highest specifications and are flexible enough to support business aspirations well into the future. What Mereside offers: 1.2m sq ft of bioscience research and office space High-specification chemistry and bioscience facilities A range of specialised technologies Vivarium Creative breakout areas Collaboration spaces for informal meetings Three breakout zones with refreshments and café-style seating Five additional coffee islands Hot-desking points with network and wifi connections Numerous meeting facilities Extensive audio visual and video conferencing facilities P.12

13 The Radnor Atrium The Atrium forms a three-storey, street style space which runs the whole length of Mereside West to create horizontal and vertical connections at all levels. The atrium features ample meeting rooms, cafe spaces, break-out areas and access to the Mereside restaurant. The fully glazed roof allows daylight to flood the space and, thanks to the use of natural floor and wall finishes gives the feeling of being connected to the outside environment. The planting of trees and the use of piazza-style seating adds to the concept of an external street, with elegant staircases and high-level glazed walkways connecting a variety of social and meeting hubs throughout the space where people can meet, work and socialise. A café-style coffee shop adds to the general buzz of the street, whilst a research lounge provides more contemplative space for solo working or ad hoc meetings. P.13

14 Alderley Park laboratory space As with the whole of the Alderley Park site, the laboratory facilities have benefited from continuous investment over the period of AstraZeneca s occupation, creating some of the best invested R&D research facilities in the country. The laboratory space has been built to a consistent high operational standard across the site, based around several central laboratory areas which each have glass-separated office and write-up space to the front of the buildings and a service corridor to the rear. Some of the laboratories have dedicated areas for specialised technologies, including an imaging suite, a compound library, high throughput screening facilities, a vivarium, cell bank, DNA bank, cell culture labs and a process development suite. All the Alderley Park laboratory spaces have been designed to handle potent materials and are equipped with extensive porting for data collection. A central building management system with configurable alarms allows remote monitoring of business-critical systems around the clock, for example freezers, environmental parameters and critical systems failures. Laboratory space facts: Over 500,000 sqft of high standard laboratory research facilities High-specification chemistry and bioscience labs Dedicated areas for specialist technologies All served by site-wide nitrogen supply (8 bar) Central building management system and configurable alarm systems Remote, round the clock monitoring of business critical systems such as freezers, environmental parameters and equipment failures P.14

15 The laboratory facilities have benefited from continuous investment, creating some of the best invested R&D research facilities in the country. P.15

16 Laboratory areas and facilities Lab area East Mereside Building numbers 14, 50, 51 & 52 Area 130,000 sq ft Primary facility High capacity compound management facility, including a solids and liquids compound store for circa 5 million compounds Other services/facilities Open-plan high throughput screening facility, linked to the compound library Specialised protein production, biochemistry structural biology labs Lab-scale fermentation processing unit suitable for biotech use Former AZ global cell bank infrastructure (Building 14) with liquid nitrogen supply, sensors and alarms etc Connectivity High-speed data transfer allowing real-time computational analysis and sample triage by scientists across the Park complex Lab area Central Mereside (General) Building numbers 8, 12 Area 92,000 sq ft Primary facility General labs designed for a range of bioscience and pharmaceutical development use Other services/facilities Fume cupboards and safety cabinets Separate office areas recently updated with a new suite of meeting rooms Service corridor with glass-washing, storage and external contractor equipment servicing facilities Connectivity High-speed data transfer allowing real-time computational analysis and sample triage by scientists across the Park complex P.16

17 East Mereside Central Mereside (General) P.17

18 Lab area Central Mereside (Specialised) Building numbers 41, 22, 23 & 24 Area 230,000 sq ft in total Building 41 (41,000 sq ft) State of the art preclinical lab for in-vivo work 18 down-flow booths Preclinical imaging suite with MRI, PET, CT, SPECT facilities Building 22 (60,000 sq ft) Former pre-clinical laboratory space Now available for refitting as lab, office space, or small scale manufacture Five-storey building with open-plan layout and great views over the Park Building 23 (68,000 sq ft) Former office and pathology facilities Pre-clinical facilities in basement Building 24 (61,000 sq ft) Former DMPK bioscience laboratory facilities 43 fume cupboards Lab area West Mereside Building numbers 33, 35 Area 99,000 sq ft in total Building 33 (58,000 sq ft) AstraZeneca s core oncology discovery centre Designed to maximise interactions between bioscience and chemistry communities Generic bioscience open plan laboratory area Designed to support state-of the-art art genomic analysis and biochemical platforms and workflows Seven modular cell culture suites that can support up to 34 cell culture users simultaneously A best-in-class medicinal chemistry capability, including an automation facility to support up to three medium-sized automated screening systems 115 fume cupboards NMR facilities (700MhZ and 500 Mhz ), with secure, open access facilities for both internal and external clients Biobank and minus 80 C storage facilities Open plan office area to accommodate up to 100 people Building 35 (41,000 sq ft) Four-storey generic open plan bioscience laboratory with best-in-class medicinal chemistry capability. Four class-ii maintained mammalian cell culture suites Two mass spectrometry suites 77 fume cupboards Radioisotope handling suite Complemented by open plan office space P.18

19 Central Mereside (Specialised) West Mereside P.19

20 The BioHub Incubator The BioHub Incubator enables start-up and early-stage bioscience companies to access the world-class facilities and resources available at Alderley Park. Operated by the specialist life science incubation company BioCity, the BioHub is effectively a collaborative R&D centre, allowing new and growing bioscience businesses to benefit from the Park s high-specification research facilities and specialist incubation support services. These services include a business bootcamp for startup companies with follow on support and mentor programmes offering a comprehensive support package. As a place to get started in bioscience, the BioHub enables new businesses to remain agile, providing office and lab space on a flexible basis and providing immediate access to the high-quality chemical and biological facilities that would normally be a prohibitively expensive business investment. P.20 As well as high-quality laboratories and offices in a range of sizes, virtual workspace is available which allows independent scientists and small teams, who may not yet be ready to take on the costs of rented physical space, to benefit from accessing the space and the full benefits of being part of the community. The BioHub is establishing a closely networked and supportive community of over 90 incubator businesses. Proactive advice and support in access to funding, shaping business plans to maximum effect and helping with client development are all areas where customers get additional value by being part of the BioHub Incubator at Alderley Park. What the BioHub Incubator offers: 85,000 sq ft of flexible office and lab space accessible on a physical or virtual basis Existing bioscience start-up community of over 90 SMEs with a presence on-site Flexible chemistry and bioscience space A programme of business learning and networking events to strengthen the on-site community Access to high quality chemical and biological facilities Specialist incubation and investment support services Access to Alderley Park Investment Funds to support new and emerging companies

21 Parklands Parklands is a beautiful, award-winning self-contained office building with a commanding view over the surrounding park and its own access and parking facilities. Built in 2003, the space is divided over five floors and is currently designed as high-quality open plan working environments to accommodate over 800 workstations. The individual floors can be redesigned/subdivided if required to provide more discrete, self-contained working environments. The ground floor currently provides a light and airy atrium that houses caféstyle catering facilities with meeting and conference facilities and informal collaboration spaces.. What Parklands offers: 103,000 sq ft of office space Meeting and conference facilities Large ground floor atrium Café-style catering Dedicated entrance/exit and car parking Open-plan accommodation that can be sub-divided if required Meeting and conference facilities Informal collaboration spaces P.21

22 Our first major redevelopment P.22

23 Situated on the eastern edge of Mereside, this important building offers a fantastic opportunity to create an extensive and highly flexible addition to the facilities in Mereside. Starting soon, this will be the first major refurbishment project undertaken by MSP on the Alderley Park site. The redevelopment will bring the building up to the standard of the rest of the estate, and create a variety of spaces suitable for either laboratory, office or manufacturing. A central circulation corridor will also allow easy access to meeting rooms, neighbouring occupiers, catering facilities and the new public courtyard. The situation is excellent, with open views across the neighbouring wood and farmland, and easy access to all on-site facilities across the Park, including the Conference Centre. The vision for the redeveloped building is to remodel all the spaces to create a new covered internal stepped courtyard providing catering facilities for the eastern end of the Mereside site. In addition, substantial new entrances will open the two ends of the building, providing strong visual impact, and access to both the site loop road and into the core of the Mereside site. Additions to the existing building will be made, taking the place of some outmoded facilities to the rear of the building. What our first new redevelopment will offer: 300,000 sq ft of newly-refurbished space Communal atrium and internal courtyard featuring new meeting and conference facilities Access to retail and cafe facilities on the Eastern edge of the site New entrances and links to Mereside campus Extensive views over the Alderley Park woodlands and farmland P.23

24 The conference centre The Alderley Park conference centre is set amongst the beautiful parkland and was designed to host the highest level of international science and business conferences and events. Alongside its superb auditorium accommodating almost 250 delegates, it offers comprehensive corporate hospitality facilities, including dining, wireless connectivity, breakout areas and exhibition space. The adaptable conference centre also has three large meeting rooms which can be opened into one large multifunctional space catering for 150 people in auditorium-style facilities. A comprehensive array of audio-visual and video conferencing facilities also allows for simultaneous presentations/ conferences with other delegates nationally and internationally. What the conference centre offers: Full suite of presentation facilities and equipment Auditorium facilities for up to 250 and rooms for delegates Breakout rooms for Video conferencing and networking facilities Multi-purpose spaces that can be used singly or in combination, in theatre or classroom style Adjoining exhibition spaces The centre has been designed to host the highest level of international science and business conferences and events P.24

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26 A wellconnected location Manchester Airport (5 Miles) Liverpool (35 miles) Motorway network Alderley Park offers a highly central location in the heart of England, providing easy access to all parts of the UK, Europe and beyond. Travel by air Alderley Park is located within 20 minutes drive time on uncongested roads to Manchester Airport which serves more destinations than any other airport in the UK. This top 20 international airport handles over 22m passengers every year to over 220 worldwide destinations allowing comprehensive direct flight access to Europe, the US and the Far East - including direct routes to China, Abu Dhabi and Singapore. More than any other regional UK airport, Manchester has multiple direct daily flights to the main U.S. hub airports including New York and Chicago and eastern hubs as shown below. It has multiple daily connections to European capital and regional airports including 18 flights to Germany a day, nine flights to Paris, eight to Amsterdam and five to the Flemish Diamond. Other international airports at Liverpool, Leeds, and Birmingham are located within 90 minutes resilient drive time of Alderley Park, as is East Midlands airport - a global freight hub facility for both DHL and UPS serving the U.S., mainland Europe and rest of the world destinations on a 24 hour basis New York New York Philadelphia PhiladelphiaChicagoChicago Charlotte Charlotte Atlanta Atlanta Washington WashingtonLas Vegas Las Vegas (JFK/Newark) (JFK/Newark) Dubai Istanbul Abu Dhabi Doha Singapore Hong Kong* * Commencing Dec London London Aberdeen AberdeenEdinburgh Edinburgh Exeter Exeter Glasgow Glasgow Norwich Norwich Inverness Inverness Newquay Newquay Heathrow Heathrow P Amsterdam AmsterdamParis (CDG) Paris (CDG) Frankfurt FrankfurtCopenhagen CopenhagenZurich Zurich Brussels Brussels

27 Manchester City Centre (12 miles) Alderley Park Travel by rail A regular shuttle service from Alderley Park provides convenient transfer from nearby Wilmslow and Macclesfield mainline stations, connecting with direct services to London that run every 20 minutes and take under two hours. Manchester is a key rail hub on the West Coast mainline linking London with Scotland as well as being the main arterial rail link between England, Wales and Scotland. Paris and Brussels are just four hours away via the London St Pancras Eurostar. Rail Connections Destination Frequency Journey Time London 3 trains per hour 2 hours Edinburgh 1 train per hour 4 hours Newcastle 2 trains per hour 3 hours Oxford 2 trains per hour 3 hours Bristol 2 trains per hour 3 hours Birmingham 2 trains per hour 1 hour 20 mins Liverpool 3 trains per hour 1 hour 10 mins Leeds 3 trains per hour 1 hour 30 mins Sheffield 2 trains per hour 1 hour 20 mins Cardiff 1 train per hour 2 hours 50 mins Substantial investment in transport infrastructure such as HS2 over the coming years will further enhance these rail connections, reducing journey times to London to just one hour. Travel by road Alderley Park is centrally located on both the UK s North/South and East/West motorway network. The main M6 motorway is just 20 minutes drive away on uncongested roads. The cities of Liverpool and Leeds can be reached within one hours drive time, with Birmingham two hours drive time from site. On-site car parks at Alderley Park can accommodate approximately 4,000 vehicles. Glasgow Edinburgh Belfast Newcastle Leeds Manchester Liverpool Sheffield Cambridge Cardiff London Alderley Park P.27

28 A great place to live and work Retail and leisure therapy, Manchester The Bridgewater Hall, Manchester P.28

29 The famous Liverpool waterfront Alderley Park is set in one of the most desirable areas in the North of England. Not only is the Cheshire countryside an area of outstanding natural beauty, it also boasts some of the best schools, housing, shopping and leisure facilities in the region. This high quality of life is reflected in the large number of wellqualified people opting to settle down in the area, particularly after graduating from many of the regions top-flight universities. Alderley Park is just 12 miles south of Manchester city centre, the UK s largest urban conurbation after London in both population and economic terms. With its rich cultural milieu of theatres, concert venues, art galleries and vast array of shops, restaurants, cafes and bars Manchester consistently tops national and international city surveys. Accolades include the Number one City in the UK (Trinity Mirror Survey 2013) and Best City in the UK to Live for three consecutive years (Economist Intelligence Global Liveability Study) ahead of New York, Rome, Milan and Singapore. Chinatown, Manchester Manchester Picadilly Gardens Alderley Park therefore offers the best of both worlds a unique parkland setting within easy striking distance of all the amenities that a vibrant European city can offer. The Manchester skyline P.29

30 A historic, natural setting for health and wellbeing What Alderley Park offers: Historic woodlands with walking and cycle paths Beautiful lakeside setting Fully-equipped gym Sports complex with football and cricket pitches, tennis and squash courts 200 acres of parkland 100 acres of farmland P.30

31 With historic records going back to the 11th century, Alderley Park offers a superb natural environment that has deep links to the past links that are still obvious to this day An authentic history The first known record of the Alderley area was in the Domesday Book of 1086, but it wasn t until 1390 that The Parks of the Lords of Alderley were first mentioned. In 1572, Alderley Park became the family seat of the Stanley family when Sir Thomas Stanley, constructed the first Alderley Hall. This building was extensively remodelled before being destroyed by fire in A new building, Alderley House, was built in 1818, followed a year later by Tenants Hall. The Stanley family sold the estate in 1938 and, after the Second World War, ICI applied for planning permission to build research laboratories on the site. The global chemical giant made Alderley Park the headquarters of its pharmaceutical division, which later became AstraZeneca. With many modern additions in recent years, there are still a number of Grade II-listed buildings on the Park, including Tenants Hall, the Dovecote and the Courtyard, all of which have been preserved in harmony with their surroundings. Health and leisure facilities Alderley Park boasts a well-equipped sports complex, enabling site occupiers to take advantage of a wide range of health and fitness facilities. From a full-sized sports hall, to cricket pitches, tennis and squash courts, there are plenty of opportunities to keep active with both indoor and outdoor activities. Membership to the gym will also give access to tailored fitness classes, a spin studio, personal training, fitness checks, health testing, physiotherapy services and sports massage. Farm and woodland areas Alderley Park remains home to a working farm and today the farm is managed as part of the overall running of the Alderley Park estate, adding significantly to the environment and atmosphere of the Park as a whole. The historic woodlands are another important feature, including the Beech Woods around Radnor Mere, which were planted by Sir Thomas Stanley around There are networks of informal woodland paths and cycle routes through other areas of the Park, forming a rich floral habitat for hundreds of native species. P.31

32 For more information or to enquire about joining the business community at Alderley Park, please call : Dr Chris Doherty, Site Director on or chris.doherty@mspl.co.uk This brochure is intended purely as a guide. The information contained within it does not form part of any offer or contract. P.32 Alderley Park Alderley Edge Cheshire SK10 4TG