EuroValve PRELIMINARY PROGRAM November 8-9, 2013 Madrid, Spain

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1 PRELIMINARY PROGRAM 2013 Course directors: José Luis Zamorano, Madrid, Spain Gilbert Habib, Marseille, France Patrizio Lancellotti, Liège, Belgium Eucomed Code of Ethical Business Practice: COMPLIANT 12 CME credits

2 Edito Dear colleagues, Synoptic We are proud to present, a new annual congress that will take place in Spain, France and Italy. This year the congress is organized by the University Hospital Ramón y Cajal in Madrid and represented by Course Directors : José Luis Zamorano, Gilbert Habib & Patrizio Lancellotti The first edition will be held in Convencion Hotel in Madrid, on November 8 & 9, As you know, valvular heart disease is getting more and more frequent and now represents one of the most frequent heart diseases. Incredible advances have occurred in the last few years about valves diseases, concerning both their evaluation and their management. New diagnostic techniques, new therapeutic strategies, new therapeutic methods are now available. From genetics to surgery, from epidemiology to transcatheter valve replacement, from echocardiography to new imaging techniques, 2013 will illustrate these most recent advances, presented by the best world specialists in valve disease The format of 2013 will be as attractive as possible, including clinical cases discussions, meet the expert sessions, controversies, symposia, and other interactive sessions. We are looking forward to meeting you in Madrid. FRIDAY NOVEMBER 8 SATURDAY NOVEMBER 9 08:30 Opening Ceremony J. L. Zamorano, G. Habib, P. Lancellotti 09:00 SYMPOSIUM Valvular Heart Disease Revolution L. Piérard, G. Maurer (Joint with EACVI) SYMPOSIUM Bicuspid aortic valve P. Tornos, V. Delgado 10:30 Coffee break on the exhibition hall Coffee break on the exhibition hall 11:00 IMAGING INNOVATIONS Advance imaging C. Fernández-Golfín, G. La Canna CASE-ORIENTED SESSION What s new and why? P. Lancellotti, O. Alfieri Organized by: Catedra de Imagen Cardiovascular José Luis Zamorano, Gilbert Habib, Patrizio Lancellotti 12:30 LUNCH SYMPOSIUM New Insights in the evaluation of LV function C. Tribouilloy, P. Tornos LUNCH SYMPOSIUM Paradigms in transcatheter valve therapy L. Pierard, G. La Canna Scientific Program Committee Giovanni La Canna, Milan, Italy Gilbert Habib, Marseille, France Patrizio Lancellotti, Liège, Belgium Luc Piérard, Liege, Belgium Christophe Tribouilloy, Amiens France José Luis Zamorano, Madrid, Spain Faculty 14:00 CASE-ORIENTED SESSION Endocarditis B. Cosyns, G. Habib 15:30 CONTROVERSIES JL. Zamorano, B. Prendergast (Joint with WGVHD) NEWS FROM VALVES GUIDELINES ESC 2012 Difficult clinical conditions to handle E. Donal, B. Iung Closing Remarks J. L. Zamorano, G. Habib, P. Lancellotti Ottavio Alfieri, Milan, Italy Jutta Bergler-Klein, Vienna, Austria Frédéric Collart, Marseille France Bernard Cosyns, Braine-L Alleud, Belgium Victoria Delgado, Leiden, The Netherlands Erwan Donal, Rennes, France Raluca Dulgeru, Bucharest, Romania Arturo Evangelista, Barcelona, Spain Khalil Fattouch, Palermo, Italy Covadonga Fernández-Golfín, Madrid, Spain Jose Juan Gomez de Diego, Madrid, Spain Alexandra Goncalves, Porto, Portugal Bernard Iung, Paris, France Julien Magne, Liege, Belgium Gérald Maurer, Wien, Austria Agnès Pasquet, Brussels, Belgium Philippe Pibarot, Québec, Canada Bernard Prendegast, Wythenshawe, United Kingdom Luis Miguel Ricon, Madrid, Spain Franck Thuny, Marseille, France Pilar Tornos, Barcelona, Spain 17:00 Coffee break on the exhibition hall 17:30 INTERACTIVE SESSIONS (Voting System) What is your diagnosis? P. Lancellotti, A. Evangelista 18:30

3 Friday November 8, :30 Opening Ceremony José Luis Zamorano, Gilbert Habib, Patrizio Lancellotti 09:00 SYMPOSIUM: Valvular Heart Disease Revolution Chairmen: Luc Piérard, Gérald Maurer (Joint With EACVI) 09:00 Epidemiology of Valvular Disease, Gérald Maurer 09:15 Biomarkers in valvular heart disease, Jutta Bergler-Klein 09:30 Multi-imaging modality approach, Covadonga Fernández-Golfín 09:45 Heart Valve Clinic, Patrizio Lancellotti 10:00 Treatment revolution of tomorrow, Giovanni La Canna 10:15 Round table discussion 10:30 Coffee break on the exhibition hall 11:00 IMAGING INNOVATIONS: Advance imaging Chairmen: Covadonga Fernández-Golfín, Giovanni La Canna 11:00 3D echo in assessment valvular morphology, Raluca Dulgheru 11:15 3D echo in assessment valvular regurgitation, José Luis Zamorano 11:30 3D echo in interventional cardiology, José Luis Zamorano 11:45 Is there a Role for CT/CMR, Victoria Delgado 12:00 Round table discussion 12:30 LUNCH SYMPOSIUM: New Insights in the evaluation of LV function Chairmen: Christophe Tribouilloy, Pilar Tornos 12:30 Aortic Stenosis, Erwan Donal 12:45 Mitral Regurgitation, Julien Magne 13:00 Pre and post valve procedures, Philippe Pibarot 13:15 Round table discussion 14:00 CASE-ORIENTED SESSION: Endocarditis Chairmen: Bernard Cosyns, Gilbert Habib 14:00 What s new in infective endocarditis, Franck Thuny 14:15 A patient with a large vegetation, Pilar Tornos 14:30 A patient with a pacemaker endocarditis, Gilbert Habib 14:45 A patient with prosthetic valve endocarditis, Bernard Prendegast 15:00 A patient treated with urgent surgery, Frédéric Collart 15:15 Round table discussion 15:30 CONTROVERSIES (Joint With WGVHD) Chairmen: José Luis Zamorano, Bernard Prendergast Part 1 Early surgery for asymptomatic severe organic mitral regurgitation PRO: The best option for all? Agnes Pasquet CON: Only when symptons develop? Gérald Maurer Part 2 Low flow / low gradient aortic stenosis with preserved LV function PRO: a silent killer? Philippe Pibarot CON: an elusive concept, Gilbert Habib 17:00 Coffee break on the exhibition hall 17:30 INTERACTIVE SESSIONS (Voting System): What is your diagnosis? Chairmen: Patrizio Lancellotti, Arturo Evangelista 17:30 Case 1: Complex Mitral Valve Prolapse, Giovanni La Canna 17:40 Discussion 1 17:45 Case 2: Complex Aortic regurgitation, Arturo Evangelista 17:55 Discussion 2 18:00 Case 3: Mitral regurgitation and LV dysfunction, Victoria Delgado 18:10 Discussion 3 18:15 Case 4: MitraClip Case, Jose Juan Gomez de Diego 18:20 Discussion 4 Saturday November 9, :30 SYMPOSIUM: Bicuspid aortic valve Chairmen: Pilar Tornos, Victoria Delgado 08:30 Epidemiology, Bernard Iung 08:50 Classification and Natural History, Agnès Pasquet 09:10 Aortic valve repair, Khalil Fattouch 09:30 Follow-up after intervention: how and when, Arturo Evangelista 09:50 Round table discussion 10:30 Coffee break on the exhibition hall 11:00 NEWS FROM VALVES GUIDELINES ESC 2012: What s new and Why? (Case-0riented Session) Chairmen: Patrizio Lancellotti, Ottavio Alfieri 11:00 Risk stratification, Luc Piérard 11:15 Aortic Stenosis, Julien Magne 11:30 Secondary Mitral Regurgitation, Bernard Cosyns 11:45 Multiple Valve Disease, Christophe Tribouilloy 12:00 Round Table discussion 12:30 LUNCH SYMPOSIUM: Paradigms in transcatheter valve therapy Chairmen: Luc Pierard, Giovanni La Canna 12:30 Which imaging techniques before TAVI? José Luis Zamorano 12:45 TAVI: alternate approaches: are there justified? Luis Miguel Ricon 13:00 Factors affecting the outcome after TAVI, Alexandra Goncalves 13:15 Round table discussion 14:00 NEWS FROM VALVES GUIDELINES ESC 2012: Difficult clinical conditions to handle Chairmen: Erwan Donal, Bernard Iung 14:00 Asymptomatic severe aortic stenosis and non-cardiac surgery, Covadonga Fernandez Golfin 14:15 Low Gradient aortic stenosis and LV dysfunction, Philippe Pibarot 14:30 Tricuspid regurgitation after left-sided valve surgery, Ottavio Alfieri 14:45 Choice of prosthesis in routine, Bernard Iung 15:00 Round table discussion 15:35 Closing Remarks, José Luis Zamorano, Gilbert Habib, Patrizio Lancellotti

4 Congress venue: HOTEL CONVENCIÓN**** O Donnell Madrid (34) F (34) More information: GETTING HERE Madrid Barajas Airport (28042 Madrid) +34(0) GETTING AROUND From the airport to Hotel Convención: 24-hrs Airport Express Shuttle Fully recommendable. Departs every 15m from each arrival terminal and needs only 2 stops. The hotel stop, 200m from the main door. Metro Tube stations can be found in T1 and T2. O Donnell tube station is only minutes away from the hotel near O Donnell Maternity Hospital. Taxi Taxi in Madrid is relatively economic around 25 from the airport. From Atocha train station - (high speed train station): If 24-hour Airport Shuttle. Hotel is located 200m away from the second stop (O Donnell) around 2. Arriving by car: Coming from A1, A2 Follow the signs towards M-30 direction A3 (Clockwise in the map). Take exit 7 C/ O Donnell. Once in O Donnell, the hotel is on your right hand side. Coming from A3, A4, A5 Follow the signs towards M-30 direction A2 (Anticlockwise in the map). Take exit 11 C/ O Donnell. Once in O Donnell, you will quickly find the 4-star hotel on your right hand side. ACCOMMODATION divine [id] has made reservations for participants at privileged rates at different hotels. To benefit from these rates, please return your housing form as soon as possible, indicating the hotel of your choice and a second choice, should the first not be available. Upon reception of the accommodation form, together with a deposit of one night accommodation, a booking confirmation letter will be sent to the participant by . The balance has to be paid one month before arrival. The daily hotel tax and any other extra are payable directly to the hotel on departure. Any booking & changes must be communicated in writing to divine [id] before September 20. A 10% administrative fee will be charged for any cancellation. After September 20, no refund will be paid. OFFICIAL LANGUAGE The official language of the sessions is English. IMPORTANT DEADLINES Hotel reservation... September 20 Pre-registration.... October 8 TARGET AUDIENCE Cardiologists Sonographers Technician and nurses Students REGISTRATION FEES Included in the registration: congress bag, final programm, access to exhibition hall, coffee break and lunches. HOTEL LIST CONVENCION HOTEL MADRID The Convencion Hotel is a 4-star structure located in a strategic situation in Madrid, close to some of its most important places, like: El Retiro, Madrid central park and the city centre. The hotel is easily and comfortably reachable with every means of transport. The hotel is characterized by a big offer of services and comforts, including: public parking, 24-hours security, luggage porter and store, doorman, concierge, shop onsite, room service and baby sitter service, as well as Wi-Fi internet connection available in the whole building. THE NH LAGASCA HOTEL The NH Lagasca hotel in Madrid is situated in the prestigious «Barrio de Salamanca», near many major sites. NH Lagasca boasts a total of 100 guest rooms: 75 Standard Rooms, and 25 Superior. It offers everything you need for a comfortable stay, whether for work or pleasure, including a generous and varied buffet breakfast, room service. Services: Free Wi-Fi, 24-hour front desk, Air-conditioned public areas, Multilingual staff, Self parking (surcharge), Parking (surcharge), Safe-deposit box at front desk, It is at 10 minutes walk to the Convencion Hotel. ORGANIZATION divine [id] agency Vérane Bergeron Moreau & Stéphanie Meyer vbergeron@divine-id.com smeyer@divine-id.com 17, rue Venture Marseille, France Tél. +33 (0) Fax +33 (0) SPONSORS

5 Registration & Housing Form Deadline: September 20, 2013 Please return to: Michèle Caboste 17, rue Venture Marseille - France Tel.: +33 (0) Fax: +33 (0) mcaboste@divine-id.com Participant Information Title: q Prof q Dr q Mr q Ms Last Name First Name Institution / Company Address Post Code City....Country... Phone...Fax... Mobile (mandatory) Speciality q Sonographer q Cardiologist q Industry professional q Technician & nurse q Resident & fellow q Other Sponsored by Contact Address Post Code...City.... Country Phone...Fax... EASIER! ATTACH YOUR BUSINESS CARD! Mobile Individual Registration Fees (VAT 21% incl.) Before September 20 After September 20 Physicians (cardiologist, sonographer, etc.) Industry professionals Nurses and Technicians, fellows and residents Hotel Accomodation (prices including breakfast, city tax not included) Single Double CONVENCION HOTEL MADRID**** NH LAGASCA**** Booking Details One night deposit is needed to confirm any hotel booking. The whole stay has to be paid before September 20 to avoid cancellation of reservation. Arrival date Departure date Type room: q Single q Double q Twin Nb. of nights Rate per night... e Cancellation before September 20: refund less 10% (administrative charge). Cancellation after September 20: no refund will be given. Name changes will be accepted before October 8. No-Shows at the congress will be charged the full fee. Refund will be processed until end of December One night deposit needed to confirm any hotel booking. The whole stay has to be paid before September 20 to avoid cancellation of reservation. City tax is not included. Total due Registration... e + Hotel q 1 night deposit q whole stay... e =...e Payment by * 3 last numbers at the back of the card q Credit Card q Visa q Mastercard (no other card) Credit Card Number security code * Expiration date Cardholder s Name... ** Your signature authorizes your credit card to be charged for the total payment due. We reserve the right to charge the correct amount if different from the total listed. q Check enclosed Please make check in Euro payable in France to divine [id] q Bank Transfer Beneficiary SARL divine [id] Bank Banque Martin Maurel IBAN FR BIC BMMMFR2A RCS Marseille B Date & signature**