The Global Viral Hepatitis Summit. Berlin, Germany June 26 28, th International Symposium on Viral Hepatitis and Liver Disease

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1 Professor Michael P. Manns, MD Congress President Preliminary Program Public Health Basic Science Prevention Diagnosis Treatment The Global Viral Hepatitis Summit 15th International Symposium on Viral Hepatitis and Liver Disease Berlin, Germany June 26 28, 2015 German Liver Foundation Joint Meeting with 12 th International HepNet Symposium (German Liver Foundation) and 1 st International TTU Hepatitis Symposium of DZIF (German Center for Infection Research)

2 TABLE OF CONTENTS WELCOME ADDRESS Welcome Address 3 Committees/Contacts 4 Acknowledgements 5 Preliminary Program Friday, June 26, Saturday, June 27, Sunday, June 28, Call for Abstracts 9 Registration 11 Accommodation 13 Congress Information 14 Travel Information 15 Imprint 18 Dear Colleagues, I have the great pleasure in inviting you to the 15 th International Symposium on Viral Hepatitis and Liver Diseases (ISVHLD) to be held from June 26 th to 28 th, 2015, in Berlin, Germany. ISVHLD has a long tradition of 43 years. Initially, it focused on the discovery of the hepatitis viruses, then on the development of diagnostic procedures and vaccines as well as on understanding the pathophysiology. Today, therapies have become the focus of research and in 2015 many of the new direct antiviral agents (DAAs) against hepatitis C will be approved. Public Health becomes increasingly important. Identification of patients in need of therapy is a major challenge to make these new therapies accessible to all parts of the world. Furthermore, we still need to develop better and finite therapies for hepatitis B and need to address many more burning issues of global relevance like hepatitis D and E. This symposium is organized every three years moving around the continents. Basic scientists and clinicians will discuss the most recent advances to combat this very important global health burden caused by all hepatitis viruses. For the first time, this symposium takes place in Germany s capital Berlin. The 15 th ISVHLD will be held together with the 12 th Annual Meeting of the German national network of competence on viral hepatitis (Hep-Net) and the 1 st International Symposium of the Hepatitis Section of the German Center for Infection Research (DZIF). It is our vision and ambition to make it a true Global Viral Hepatitis Summit. We look forward to welcoming you in Berlin in June Photo: 4designersart - Fotolia.com Key Dates to Remember Online registration opening: September 2014 Online abstract submission opening: September 2014 Abstract submission deadline: March 9, 2015 Notification of accepted abstracts: May 2015 Professor Michael P. Manns, MD Congress President, ISVHLD

3 COMMITTEES/CONTACTS ACKNOWLEDGEMENTS Congress President Professor Michael P. Manns, MD Department of Gastroenterology, Hepatology and Endocrinology Internal Medicine Hannover Medical School Carl-Neuberg-Strasse Hanover, Germany International Advisory Committee Pei-Jer Chen, Taiwan Adrian M. Di Bisceglie, USA Gamal Esmat, Egypt Xavier Forns, Spain Jorge Enrique González, Argentina F. Blaine Hollinger, USA Jay H. Hoofnagle, USA Harry L. A. Janssen, Canada Stephen A. Locarnini, Australia Michael P. Manns, Germany Masao Omata, Japan Subrat Kumar Panda, India Charles M. Rice, USA David L. Thomas, USA Howard C. Thomas, United Kingdom Christian Trepo, France John W. Ward, USA Stefan Z. Wiktor, Switzerland Zhenghong Yuan, China National Advisory Committee Ralf Bartenschlager, Heidelberg Peter Buggisch, Hamburg Sandra Ciesek, Hanover Markus Cornberg, Hanover Hans Peter Dienes, Vienna Dirk Heinz, Braunschweig Ulrich Kalinke, Braunschweig Martin Krönke, Cologne Thomas Mertens, Ulm Claus Niederau, Oberhausen Thomas Pietschmann, Braunschweig Ulla Protzer, Munich Elke Roeb, Giessen Michael Roggendorf, Essen Peter Schirmacher, Heidelberg Thomas von Hahn, Hanover Heiner Wedemeyer, Hanover Stefan Zeuzem, Frankfurt Legal Organizer (PCO) MCI Deutschland GmbH MCI Berlin Office Markgrafenstrasse Berlin, Germany Phone: +49 (0) Fax: +49 (0) isvhld@mci-group.com Project Management Juliane McCarty Phone: +49 (0) isvhld@mci-group.com Scientific Secretariat Astrid Schörnig Phone: +49 (0) isvhld-secretariat@mci-group.com Industrial Exhibition, Symposia and Sponsoring Iohanna Vater Phone: +49 (0) isvhld-sponsoring@mci-group.com Registration and Accommodation Phone: +49 (0) registration@mci-group.com The organizers of ISVHLD 2015 gratefully acknowledge the support of the following associations that have endorsed this congress: American Association for the Study of Liver Diseases (AASLD) Latin American Association for the Study of the Liver (ALEH) European Association for the Study of the Liver (EASL) German Center for Infection Research (DZIF) Asian Pacific Association for the Study of the Liver (APASL) International Association for the Study of the Liver (IASL) German Liver Foundatio n German Liver Foundation (DLS)

4 PRELIMINARY PROGRAM PRELIMINARY PROGRAM Friday, June 26, 2015 Saturday, June 27, :00 AM 8:00 AM 9:00 AM Breakfast Sessions 8:15 AM 9:45 AM 10:00 AM Opening Ceremony 11:00 AM Public Health Session I 10:30 AM 12:00 PM 10:00 AM 10:30 AM 12:00 PM Lunch Symposia 1:00 PM 2:00 PM 3:00 PM 4:00 PM 5:00 PM 6:00 PM 7:00 PM HCV I: Basic Science I 1:00 PM 2:30 PM HCV II: Prevention 3:00 PM 4:30 PM HDV I: Basic Science 1:00 PM 2:30 PM HDV II: Diagnosis and Treatment 3:00 PM 4:30 PM Industry Symposia 5:00 PM 6:30 PM 12:00 PM 1:00 PM HepNet Symposium: Hepatology General 1:00 PM 2:30 PM Coffee Break HepNet Symposium: Partner Sessions 3:00 PM 4:30 PM Coffee Break HepNet Symposium: Partner Sessions 5:00 PM 7:00 PM Public Health Session II 1:00 PM 2:30 PM Public Health Session III 3:00 PM 4:30 PM Public Health Session IV 5:00 PM 6:30 PM Free Paper Parallel Session 1:00 PM 2:30 PM Free Paper Parallel Session 3:00 PM 4:30 PM 9:00 AM HBV I: Basic Science and Natural 10:00 AM History 11:00 AM 12:00 PM 1:00 PM 2:00 PM 3:00 PM 4:00 PM 5:00 PM 6:00 PM 9:00 AM 10:30 AM HBV II: Diagnosis and Treatment 11:00 AM 12:30 PM HAV 2:00 PM 3:30 PM Hepatitis Non A E 4:00 PM 5:30 PM HEV I: HEV Virology, Pathogenesis and Diagnosis 9:00 AM 10:30 AM Coffee Break HEV II: Epidemiology 11:00 AM 12:30 PM HEV III: Natural History 2:00 PM 3:30 PM Coffee Break HEV IV: Treatment, Vaccination 4:00 PM 5:30 PM HepNet Symposium: Partner Sessions 8:00 AM 10:30 AM HepNet Symposium: Hepatology General 11:00 AM 12:30 PM Lunch Symposia 12:45 PM 1:45 PM DZIF I 2:00 PM 3:30 PM DZIF II 4:00 PM 5:30 PM Congress Evening 6:00 PM 8:00 PM Science Workshop 9:00 AM 12:30 PM Public Health Working Groups 2:00 PM 5:30 PM Free Paper Parallel Session 9:00 AM 12:30 PM Free Paper Parallel Session 2:00 PM 5:30 PM Welcome Reception & Poster Session 7:00 PM 8:30 PM Program is subject to change. Hepatitis A Virus/Science AGs Hepatitis Non A E Poster/Free Paper Hepatitis B Virus HepNet Symposium Parallel Session Hepatitis C Virus Public Health Session Industry Sponsored Session Hepatitis D Virus German Center for Infection Others Hepatitis E V irus Research (DZIF) Symposium

5 PRELIMINARY PROGRAM CALL FOR ABSTRACTS Sunday, June 28, :00 AM 9:00 AM 10:00 AM 11:00 AM 12:00 PM 1:00 PM 2:00 PM 3:00 PM HCV III: Treatment 10:00 AM 12:00 PM HBV III: Diagnosis and Treatment 10:00 AM 12:00 PM Breakfast Sessions 8:15 AM 9:45 AM Coffee Break DZIF III 10:00 AM 12:00 PM General Session and Closing 1:00 PM 3:00 PM Farewell Coffee/Meet the Experts/Clinical Workgroups 3:00 PM 5:00 PM Program is subject to change. Free Paper Parallel Session 10:00 AM 12:00 PM Start preparing your abstract for the 15 th International Symposium on Viral Hepatitis and Liver Diseases (ISVHLD)! The Global Viral Hepatitis Summit draws numerous delegates with it s top-quality scientific content presented in a variety of session formats. Make sure to be part of this successful symposium and submit your abstract online before March 9, 2015! Abstract Submission Please select one category from the following list that best describes the content of your abstract. The category is used for reviewing and indexing purposes. Hepatitis A Hepatitis B Hepatitis C Hepatitis D Hepatitis E Hepatitis Non A E Please note that only electronic submission will be accepted. Faxed or mailed abstracts will not be reviewed. For further information please check Preparation of your Abstract Abstracts must be submitted in English (max. 3,000 characters incl. spaces) All abstracts must contain original work that has not been published before Indicate the preferred type of presentation (oral or poster) The title should be as brief as possible but long enough to indicate clearly the nature of the study Tables and graphics can be used (maximum of two each) Please check spelling and grammar carefully. All abstracts will be published as submitted Use generic names. Commercial drug names may not be used Hepatitis A Virus/Science AGs Hepatitis Non A E Poster/Free Paper Hepatitis B Virus HepNet Symposium Parallel Session Hepatitis C Virus Public Health Session Industry Sponsored Session Hepatitis D Virus German Center for Infection Others Hepatitis E V irus Research (DZIF) Symposium

6 CALL FOR ABSTRACTS REGISTRATION The online registration portal opens in fall To register, please visit You can either register online or download the registration form provided on the symposium website. Registration Fees Early Late On-site until 03/26/2015 from 03/27/2015 until 05/26/2015 Delegates Students* Assoziierte der Deutschen Leberstiftung PI der TTU Hepatitis * Registration forms must be accompanied by written proof of status; otherwise low fees will not be validated Oral Presentations Computer projection facilities (PowerPoint presentations) will be available in all meeting rooms. MCI will provide further information prior to the symposium. Poster Presentations Selected posters will be discussed in guided poster walks. Posters should be prepared in portrait format and English language. Further information will be provided prior to the symposium on Registration All authors are kindly asked to register at the early bird rate until March 26, Please note that the acceptance of your abstract does not include congress registration. At least one author (the first or the presenting author) is therefore kindly asked to register for the symposium. The abstract will otherwise not be reviewed and excluded by the scientific committee. Contact Astrid Schörnig Scientific Secretariat Phone: +49 (0) Fax: +49 (0) isvhld-secretariat@mci-group.com Registration fee covers Admission to scientific sessions, poster exhibition and industrial exhibition Collection of abstracts (on CD-ROM) Congress bag with documents Opening ceremony and welcome reception & poster session All fees are indicated in EUR, incl. VAT. Registration on-site is possible during the entire symposium within the opening hours of the registration counters. Registration and services booked can only be confirmed after receipt of full prepayment or valid credit card details. Cancellation Policy In case of cancellation of participation until March 26, 2015 registration fees will be refunded deducting a handling fee of 32 per person. The registration is nonrefundable after that date. Name changes will be charged with 16 per registration. In case of any special requests for the processing of your invoice, kindly let us know when returning your registration form. For the rewriting of invoices 16 will be charged. Method of Payment Payments should be made by credit card (American Express Eurocard/MasterCard, Visa) by direct debit order, via German bank accounts only by cash (on-site only)

7 REGISTRATION ACCOMMODATION Participants are kindly asked to make hotel reservations by using the online registration portal on the congress website. Hotel reservation is also possible via fax or regular mail. The registration form and further information are available at The selected hotels have limited capacities. It is recommended to make your hotel booking as early as possible. Distance to Hotels Single room Double room Estrel TXL/SXF airport Estrel Berlin**** km 17 km 13 km Mercure Hotel Berlin Tempelhof Airport**** km 15.7 km 12.9 km Park Hotel Blub**** km 18.9 km 9.3 km Ibis Berlin Neukölln*** km 18.7 km 9.8 km * Rates per room and night including breakfast and German VAT. Letter of Invitation Those persons needing an official invitation letter in order to attend the symposium may contact the scientific secretariat specifying the necessary details: isvhld-secretariat@mci-group.com This service is designed only to assist participants who need to obtain a visa or permission to attend the symposium. The letter of invitation does not financially obligate the conference organizers in any way. All expenses incurred in relation to the conference are the sole responsibility of the attendee. Visa Requirements It is the sole responsibility of the attendee to take care of his/her visa requirements. Attendees who require an entry visa must allow sufficient time for the application procedure. Attendees should contact the nearest embassy or consulate to determine the appropriate timing of their visa applications. The organizers will not directly contact embassies and consulates on behalf of visa applicants. Group Registration If you are interested in registering groups of 10 or more delegates, please contact MCI Deutschland GmbH for further information at isvhld@mci-group.com. Contact MCI Deutschland GmbH MCI Berlin Office Markgrafenstrasse Berlin, Germany Phone: +49 (0) Fax: +49 (0) isvhld@mci-group.com Method of Payment All nights will be charged upon registration. All extras have to be paid directly at the hotel upon check-out. The city of Berlin has introduced a city tax. Business travellers are exempt from the city tax. They do, however, have to be able to prove the business purpose of their trip. This can be verified by a bill that is paid by or issued to the employer, or a letter from the company. The following credit cards are accepted: MasterCard, Visa, and American Express. If the desired hotel is already fully booked, MCI Deutschland GmbH reserves the right to arrange accommodation in another hotel. Cancellation Policy Cancellations or changes should be received in writing to MCI Deutschland GmbH by or fax. In case of changes a handling fee ( 30) applies. Please do not contact the hotel directly. Cancellation of room/nights received before March 26, 2015 Refund deducting a 40 cancellation fee Cancellation of room/nights received until April 23, 2015 Cancellation of one night: no refund Cancellation of two or more nights: 50% refund of booked nights Cancellation of room/nights received from April 23, 2015 or no-show No refund

8 CONGRESS INFORMATION TRAVEL INFORMATION Dates June 26 28, 2015 Language The official language is English. All presentations have to be prepared in English only. There will be no simultaneous translation. Accreditation Accreditation for credits will be made. More information to follow on the congress website Schedule Your Congress Online Make the most of your time at ISVHLD use the online program planner! Select the sessions you want to attend and see them automatically in your personal planner. Create your personal appointments, export your schedule into your calendar or simply print it out. Start planning today on Exhibition The scientific meeting will be accompanied by a comprehensive industrial exhibition covering the latest developments in Public Health, Basic Science, Prevention, Diagnosis and Treatment. Companies interested in joining the exhibition are kindly asked to contact MCI Deutschland GmbH at isvhld-sponsoring@mci-group.com. Time Germany operates on Central European Time (CET), which is 1 hour ahead of Greenwich Mean Time (GMT) and 6 hours ahead of Eastern Standard Time (EST) in the United States. Official times like shop hours or train schedules are usually indicated by the 24-hour clock, means 7:30 pm is 19:30. Money The Euro is the official currency in Germany. You can change money at banks, post offices and currency exchanges in airports or train stations. Classic credit cards, such as American Express, Master Card, Diners Club or VISA are rarely used, but accepted by major hotels, petrol stations or large shops. Otherwise cash or Eurocheque cards will be accepted. Most banks work with international ATM networks like Cirrus, Plus, Star and Maestro. Electricity European electric sockets are designed with two round pin plugs and work with 230 Volts AC, 50 Hz. You might need a plug and a transformer, which fit the German socket. Climate Germany belongs to the temperate zone, which requires a wardrobe as flexible as possible. In summer, the thermometer reaches temperatures about 25 C/77F, but deviations are not unusual. The humidity level is mostly high. Estrel Berlin Hotel & Convention Center Congress Venue Estrel Berlin Hotel & Convention Center Sonnenallee Berlin, Germany Air Travel Berlin hosts two international airports Tegel (TXL) and Schönefeld (SXF). Tegel is situated in the north-west of the city and Schönefeld in the south-east. For detailed flight connections, please visit From Tegel Airport take the X9 bus line to Jungfernheide bus stop. Transfer to the S42 commuter train line (Ringbahn) and get off at Sonnenallee. It takes about 40 minutes to reach the Estrel Berlin by public transport and about 30 minutes by car. From Schönefeld Airport take the 171 bus line until you reach "Sonnenallee". It takes about 40 minutes by bus and about 15 minutes by car to reach the Estrel Berlin. Road Travel Whether you are approaching the venue on motorway A100 or A113, use exit 26, Grenzallee and turn right The Estrel Berlin Hotel & Convention Center s convenient location makes it easy to reach by car and public transport. The nearest slip road to the highway is only 1.5 km, and Schönefeld Airport (SXF) only 13 km away. The Sonnenallee S-Bahn commuter train station can be reached by foot in only three minutes, and a bus stop and taxi rank are located right in front of the hotel. at the traffic light onto the street called Grenzallee. Continue on Grenzallee for two more traffic lights, turning left at the second one onto the street called Sonnenallee and proceed for another half a kilometer where you will find the Estrel Berlin located on the right side of the street. Parking Facilities The hotel has its own underground parking garage offering 450 parking spaces (maximum 18 per day). Rail Travel In cooperation with MCI Deutschland GmbH and Deutsche Bahn you travel environment- and climate-friendly to the 15 th International Symposium on Viral Hepatitis and Liver Disease! Deutsche Bahn guarantees to only use energy from 100% renewable sources for your journey. Up to three days prior to the event the event ticket for a return trip to Berlin from anywhere in Germany: 2 nd class 99 1 st class 159 Please note that only a limited number of tickets is available and that certain conditions and limitations apply. Deutsche Bahn call center is glad to

9 TRAVEL INFORMATION NOTES inform you about the ticket price for international journeys. Your ticket is valid from June 24 30, To book call +49 (0) ** and quote MCI as reference. Please have your credit card ready while booking. Alternatively, you can also purchase tickets online at Veranstaltungsticket. Your booking will be binding after Deutsche Bahn s confirmation. Public Transport Located near the M41 bus stop Ziegrastrasse and the commuter train stop (S41 and S42) Sonnenallee, the venue can be reached easily from anywhere in the city. Ticket vending machines can be found at any train or metro station or you can purchase your ticket directly from the bus driver. For more information on public transport tickets and on how to plan your trip, please visit Estrel Berlin Hotel & Convention Center Hamburg 111 Airport Tegel Hauptbahnhof Stettin 114 PRENZLAUER BERG Messe FRIEDRICHS- Berlin MITTE HAIN TIERGARTEN Ostbahnhof KREUZBERG CHARLOTTEN- BURG NEUKÖLLN Potsdam Airport Berlin Schönefeld Hannover 113 Dresden

10 IMPRINT Congress President Professor Michael P. Manns, MD Department of Gastroenterology, Hepatology and Endocrinology Internal Medicine Hannover Medical School Photo: Sebastian Kaulitzki - Fotolia.com Legal Organizer (PCO) MCI Deutschland GmbH MCI Berlin Office Markgrafenstrasse Berlin, Germany Congress Website Editors Professor Michael P. Manns, MD MCI Deutschland GmbH Graphic Design MCI Deutschland GmbH As of August 26, 2014, Program is subject to change. 18

11 See you in Berlin! June 26 28,

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