Bi190 Mating Type Interconversion
|
|
|
- Terence Heath
- 5 years ago
- Views:
Transcription
1 Ir Herskowitz Bi190 Mting Type Interconversion 2007 Sternberg, Cltech
2 Scchromyces cerevisie (budding yest) Life Cycle mting / zygote sporultion -C -N germintion +C +N Ascus with 4 spores hploid cells
3 specific genes Production of fctor Agglutintion Response to -fctor non specific genes Response to pheromones specific genes mting mting Production of - fctor Agglutintion Response to fctor
4
5 Scchromyces cerevisie (budding yest) Life Cycle mting / zygote sporultion -C -N germintion +C +N Ascus with 4 spores hploid cells
6 Homothllism: single hploid spore gives rise to diploid cells tht cn undergo meoisis nd sporultion cells (-fctor producing) shmoos zygotes / / / / ho HO
7 The genetic elements controlling mting type interconversion were defined by nturl vrints. In current nomenclture: S. cerevisie HML MAT HMR ; HO S. cerevisie HML MAT HMR ; ho S. oviformis HML MAT HMR ; HO S. norbensis HML MAT HMR ; HO S. distticus HML MAT-inc HMR ; HO
8 HO is necessry for Diploidiztion MAT MAT HO ho HO Dip(loidizer) ho -mter HO Dip ho mter Tetrtype Ascus
9 HMR is necessry for to HML MAT HMR ; HO HML MAT HMR ; HO Dip HML MAT HMR HO Dip HML MAT HMR HO Dip HML MAT HMR HO HML MAT HMR HO Dip HML MAT HMR HO Dip HML MAT HMR HO Dip HML MAT HMR HO Dip HML MAT HMR HO Dip
10
11 Mting Type Interconversion: the moleculr level 200 kb 150 kb HML MAT HMR CEN III HO E I W X Y ZL W X Y Z X Y ZR E I W Y Y Z L Z R ~700 bp ~600 bp ~750 bp ~300 bp ~250 bp HO cuts t ~18 bp site -inc is the site The event is non-reciprocl --the cssette is lost. Gene Conversion vi double-strnd brek repir
12 Tests of the cssette model In 10% of the 10-6 ho switches, There is deletion, clled -lethl or Hwthorne deletion: this is fusion of MAT to HMR HML MAT HMR
13 Tests of the cssette model Heling: HO HML mt1-5 HMR Sterile cn switch to n -mter Wounding: HO HML 66 MAT HMR -mter switches from to Ste to to Ste
14 Mting Type Interconversion: the moleculr level 200 kb 150 kb HML MAT HMR CEN III HO E I W X Y ZL W X Y Z X Y ZR E I W Y Y Z L Z R ~700 bp ~600 bp ~750 bp ~300 bp ~250 bp HO cuts t ~18 bp site -inc is the site E, essentil for silencing I, importnt for silencing The event is non-reciprocl --the cssette is lost. Gene Conversion vi double-strnd brek repir
15 Tests of the cssette model mutgenize: ho HML mt1-5 HMR Sterile pick -mter sir1-1 (silent regultor) nlyze: ho HML mt1-5 HMR ; sir1-1 -mter ho HML mt1-5 HMR ; sir1-1 Sterile So, it depends on HML!
16 Jsper Rine: sir1-1 sir1-1 Spo+ Thus, HML cn provide function sir1 sir2 = mr1 sir3 = ste8 = cmt sir4 = ste9 The SIR proteins silence the HML nd HMR loci
17 Mting Type Interconversion: the moleculr level 200 kb 150 kb HML MAT HMR CEN III HO E I W X Y ZL W X Y Z X Y ZR E I W Y Y Z L Z R ~700 bp ~600 bp ~750 bp ~300 bp ~250 bp HO cuts t ~18 bp site -inc is the site E, essentil for silencing I, importnt for silencing The event is non-reciprocl --the cssette is lost. Gene Conversion vi double-strnd brek repir
18 Pedigree nlysis mother dughter mother dughter Shmoo (G1 rrest t START) or but not / cells switch Only mothers switch Switching in pirs Directionlity: to to Strthern, Hicks & Herskowitz (Cell 1979)
19 Pedigree nlysis mother dughter mother dughter or but not / cells switch Only mothers switch Switching in pirs HO is Off in / cells Off in dughters On in lte G1 Nsmyth (1983)
20 Pedigree nlysis mother dughter mother dughter SWI+ SIN+ swi5 SIN3+ SWI5+ sin3
21 HO expression in mother versus dughter cells ASH1 is trnscriptionl repressor only in dughter cell nuclei ASH1 protein is unstble ASH1 mrna is loclized preferentilly to dughter cells. The SHE proteins re necessry for ASH1 mrna locliztion SHE1 (MYO4) encodes non-muscle myosin
22 Figure 3. The Effect of the she Mutnts on Prticle Locliztion nd Formtion Yest strins disrupted for ech one of the five SHE genes were trnsformed with the ASH1 reporter RNA nd the GFP-MS2 fusion protein nd the resultnt prticles observed by epifluorescence fter fixtion. Br, 5 mm. (A) Wild-type cells (K699). Locliztion of the prticle nd its formtion is inhibited in (B) she5 deletion strin (K5205): 36% of cells with signl formed bright, single prticles; pproximtely hlf of the prticles were loclized t the bud neck nd 2% were loclized in the bud. (C) she3 deletion strin (K5235): 6% formed bright, single prticles nd 0% were loclized in the bud. (D) she1 deletion strin (K5209): 16% of cells with signl formed bright, single prticles nd 0% were loclized in the bud. (E) she2 deletion strin (K5547): 0% formed bright, single prticles nd 0% were loclized in the bud. (F) she4 deletion strin (K5560): 32% formed bright, single prticles nd 16% with signl were loclized in the bud. Colocliztion (yellow) of functionl myctgged she protein (red) with the prticle (green). (G) She1myc. (H) She2myc. (I) She3myc. (J I) She1myc with nonloclized prticle in nonbudding cell. (Hlf of the prticles showed colocliztion with She1myc.) Moleculr Cell, Vol. 2, , October, 1998
23 Directionl switching: there is recombintionl enhncer on the left rm of III tht is ctivted in but not cells. (see Hber Annul Review of Genetics) HML RE CEN3 MAT HMR
24 Hber (Ann Rev Genetics 1998)
Bi190 Mating Type Interconversion
Ir Herskowitz Bi190 Mting Type Interconversion 2011 Sternberg, Cltech Scchromyces cerevisie (budding yest) Life Cycle mting / zygote sporultion -C -N Ascus with 4 spores germintion +C +N hploid cells specific
Supplementary Figure 1. Representative controls for DSB induction efficiency in wild-type
Supplementary Figure 1. Representative controls for DSB induction efficiency in wild-type and mutant cells. Representative spotting assay reveals that the tested deletions do t affect the efficiency of
Project Summary. Principal Investigators: John Scanga, Ph.D., John Sofos, Ph.D., Keith Belk, Ph.D. and Gary Smith, Ph.D., Colorado State University
Project Summry Decontmintion of Beef Cuts Intended for Blde/Needle or Moisture-Enhncement Tenderiztion by Surfce Trimming versus Rinsing with Solutions of Hot (82 C) Wter, Wrm (55 C) Lctic Acid or Activted
The xanthophyll cycle affects reversible interactions between PsbS and light-harvesting complex II to control non-photochemical quenching
In the formt provided y the uthors nd unedited. SUPPLEMENTARY INFORMATION VOLUME: 3 ARTICLE NUMBER: 16225 The xnthophyll cycle ffects reversile interctions etween PsS nd light-hrvesting complex II to control
Bacteria Associated with Granular Activated Carbon Particles in Drinking Water
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Sept. 1986, p. 434-438 0099-2240/86/090434-05$02.00/0 Copyright 1986, Americn Society for Microbiology Vol. 52, No. 3 Bcteri Associted with Grnulr Activted Crbon
Calculate the length, correct to 1 decimal place, of the unmarked side of the triangle at right.
5 Trigonometry I WORkED ExAMPlE 2 Clculte the length, correct to 1 deciml plce, of the unmrked side of the tringle t right. 8 cm 14 cm On Clcultor pge, to solve equtions press: MENU 3: Alger 3 1: Solve
Corporate Champions Package
Corporte Chmpions Pckge 2017 The Alice Ferguson Foundtion is in its second yer of our Corporte Chmpions Cmpign, designed to grner sustined support for the thousnds of re students served ech yer through
Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3domain
(2005) 24, 8187 8199 & 2005 Nture Pulishing Group All rights reserved 0950-9232/05 $30.00 www.nture.com/onc Trnsctivtion of Al y the Crk II dpter protein requires PNAY sequence in the Crk C-terminl SH3domin
Thermo Scientific Nalgene Rapid-Flow Filters. the last line of defense. against contamination
Nalgene Rapid-Flow Filters the last line of defense against contamination The Rapid-Flow Advantage. From the outside, bottle top filters look alike. But, when you look beneath the membrane, glaring differences
Special edition paper Development of a Crew Schedule Data Transfer System
Development of a Crew Schedule Data Transfer System Hideto Murakami* Takashi Matsumoto* Kazuya Yumikura* Akira Nomura* We developed a crew schedule data transfer system where crew schedule data is transferred
VIABILITY AND FECUNDITY OF ALATE ALIENICOLAE OF APHIS FABAE SCOP. AFTER FLIGHTS TO EXHAUSTION BY A. J. COCKBAIN
I '. Exp. Biol. (1961), 3, 11-17 'ith 2 text-figures Printed in Gret Britin ll VIABILITY AND FECUNDITY OF ALATE ALIENICOLAE OF APHIS FABAE SCOP. AFTER FLIGHTS TO EXHAUSTION BY A. J. COCKBAIN Rothmsted
Look inside to learn why an X-GLOO Inflatable Event Tent is the perfect solution for your event!
EN THINK OUT OF THE BO The X-GLOO Infltble Event Tent offers highly-customizble solution for housing your disply, presenttion or event in ny loction indoors or out. With wide rnge of sizes nd the bility
Waterproof Switches 01
Waterproof Switches SL 9 BMASK 9 SA 9 RMASK 96 SLR 98 9 SWITCHES SL TYPICAL APPLICATIONS Steam cleaners S SPST, momentary or not SPST, illuminated or not DPST, momentary or not DPST, illuminated or not
Mathematics of Flight. Glide Slope II
Mthemtics of Flight Glide Slope II A glider is specil kind of ircrft tht hs no engine. The Wright brothers perfected the design of the first irplne nd gined piloting experience through series of glider
Dry Rehydratable Film Method for Rapid Enumeration of Coliforms in Foods (3M Petrifilm Rapid Coliform Count Plate): Collaborative Study
56 KINNEBERG &LINDBERG:JOURNAL OF AOAC INTERNATIONAL VOL. 85, NO. 1, 2002 70-2009-6428-9 FOOD BIOLOGICAL CONTAMINANTS Dry Rehydrtle Film Method for Rpid Enumertion of Coliforms in Foods (3M Petrifilm Rpid
Help Need Scan and other data
Cruise Florida Ships Reference No CR1001 Admiral Cruises Cruise Ship Stardancer under 5 stars DC $1.00 1989 GD CN Page 1 Reference No CR1002 American Casino Cruises Cruise Ship Ship with 2 dice DC $0.25
Molecular characterization of Italian Soil-borne cereal mosaic virus isolates
11 Parasitica, 2005, 61(1):11-16 Molecular characterization of Italian Soil-borne cereal mosaic virus isolates C. RATTI 1, A. PISI 1, V. VALLEGA 2 & C. RUBIES AUTONELL 1 1 Department of Agroenvironmental
User manual for awning blind AMZ Z-Wave
GB User manual for awning blind AMZ ZWave Contents 1. Safety standards...2 2. Description...3 3. Programming the appliance...4 4. Association Groups...5 5. Compatibility of other producers appliances in
Incarnation Monastery Guest House. Guest House Plan & Vision Sept 28, 2013
Incarnation Monastery Guest House Guest House Plan & Vision Sept 28, 2013 Current State Guest house revenue for 2012 $20,000 Guest house revenue for Jan-Jun 2013 $10,000 No change from 2012 Current occupancy
NLTF 2020/21 ($000) Funding Priority NLTF 2018/19 ($000) NLTF 2019/20 ($000)
Funding Priority Wellington - Carterton District Council - Local road improvements Low cost / low risk improvements 2018-21 Local Roads 2 341 HM 53% 1,050 194 149 214 Approved Street Light LED conversion
Antibiotic Resistance Among Coliform and Fecal Coliform
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, June 1976, p. 879-884 Copyright C 1976 Americn Society for Microbiology Vol. 9, No. 6 Printed in U.SA. Antibiotic Resistnce Among Coliform nd Fecl Coliform Bcteri
7-Nov-15 PHYS Elastic Collision. To study the laws of conservation of momentum and energy in an elastic collision. Glider 1, masss m 1.
Objective Elastic Collision To study the laws of conservation of momentum and energy in an elastic collision. Introduction If no net external force acts on a system of particles, the total linear momentum
(1) Use given triangle to fill in the blank. A = b c c. (1) A = b c. tan cos sin
0/3/206 Print Questions. Use given tringle to fill in the lnk. = () = () tn os sin 2. Write the rtios for sin M, os M, nd tn M. Give the ext vlue nd four deiml pproximtion. M K 23 2 02 L Type the deiml
Examining hand grip strength in different sports
Interntionl Journl of Sport Studies. Vol., 5 (10), 1132-1136, 2015 Aville online t http: www.ijssjournl.com ISSN 2251-7502 2015; Science Reserch Exmining hnd grip strength in different sports Onder Krkoc
The Impressive Increase in Throughput of the illumina Genome Analyzer, as Seem from an User Perspective
The Impressive Increase in Throughput of the illumina Genome Analyzer, as Seem from an User Perspective Laurent FARINELLI 31 August 2009 Illumina Seminar 55 Congresso Brasileiro de Genética Águas de Lindóia,
Leonardo Hotels Shay Raz- MBA VP Rev Mgt & Development
Leonardo Hotels Shay Raz- MBA VP Rev Mgt & Development Revenue Management Transformation Adopting Systems Effectively Change can make or break organisations, from the smallest switch to corporate overhaul,
Offer period: 15 June August 2018.
Dear Members We are pleased to inform that Resort World Genting is offering RM5.00 per China Tourist invited by licensed Tourist Guides to Sky Casino Sliver Club Dragon Room. Offer period: 15 June 2018-15
THE MTA100 THE NEXT 100 YEARS STARTS HERE
100 NEXT 100 YEARS STARTS HERE is hosting 100 country s biggest ever vehicle show ntionlly significnt event celebrte its centenry. Kiwis hve been in love with crs since first two Benz were imported New
Quad-Lock Container System. sterilization solutions. Symmetry Surgical s Quad-Lock container. system now features NEW sterilization modalities
sterilization solutions Symmetry Surgical s Quad-Lock container system now features NEW sterilization modalities with a patented, advanced design engineered to ensure dependable lid attachment. Four latches
Alpha Systems AOA Classic & Ultra CALIBRATION PROCEDURES
Alpha Systems AOA Calibration Overview The calibration of the Alpha Systems AOA has 3 simple steps 1.) (On the Ground) Zero calibration 2.) (In-flight) Optimum Alpha Angle (OAA) calibration 3.) (In-flight)
Comprehensive analysis of SET domain gene family in foxtail millet identifies the putative role of SiSET14 in abiotic stress tolerance
Comprehensive analysis of SET domain gene family in foxtail millet identifies the putative role of SiSET14 in abiotic stress tolerance Chandra Bhan Yadav, Mehanathan Muthamilarasan, Anand Dangi, Shweta
MEASUREMENT OF ACCELERATION Pre-Lab. Name: Roster#
MEASUREMENT OF ACCELERATION Pre-Lab Name: Roster# Date: 1. A tree is 15.0 m high and cast a shadow along the ground that is 30.0 m long. Draw a triangle that represents this situation. What angle does
COFRE 600 VOLANTE INSTALLER AND USER S MANUAL
COFRE 600 VOLNTE INSTLLER ND USER S MNUL v1.1 REV. 12/2014 00. CONTENT 01. SFETY INSTRUCTIONS INDEX STNDRDS TO FOLLOW 00. CONTENT índice page 01. 01. SFETY INSTRUCTIONS standards to follow page 01. 02.
Model Number Structure
Solid State Relays Refer to Safety Precautions for All Solid State Relays. Extremely Thin Relays Integrated with Heat Sinks Downsizing achieved through optimum design of heat sink. Mounting possible via
Fiber Optic Laryngoscopes G-Profile Blades
G-Profile Blades SunMed s Fiber Optic German Profile laryngoscope blades are built with an integral, extra large fiber optic bundle providing a more cool, white light. This integral design enables superior
Utility Knives & Blades
www.irwin.com Utility Knives & Blades Utility Blades IRWIN 4-Point Snap Blades The new IRWIN 4-Point snap blade combines the toughness of a traditional blade with the functionality of a snap blade. When
Last Name. M52080 Soft healing cap 2 M52080 Soft healing cap 2 Ponto BHX Implant, 4mm *H with abutment, 9mm. After Care Kit M51177
SHIP TO Customer No. (Please complete all information including name and phone number) Phone # Fax # Clinic Name _ Address _ City _ State Zip PO# BILL TO (If different than SHIP TO) Customer No. Company
Lesson 12.2 Problem Solving with Right Triangles
Lesson 12.1 rigonometric tios In Eercises 1 6, give ech nswer s frction in terms of p, q, nd r. 1. sin 2. cos 3. tn 4. sin Q 5. cos Q 6. tn Q p In Eercises 7 12, give ech nswer s deciml ccurte to three
What is Systems Biology?
Lecture 13 Systems Biology Saleet Jafri What is Systems Biology? In traditions science a reductionist approach is typically used with an individual system or subsystem is dissected and studied in detail
Regulatory update Air operations
Regulatory update Air operations Willy Sigl EASA DEKRA Berlin, Germany 22 May 2014 European Aviation Regulations ATM/ANS: air traffic management, air navigation services TCO: third country operators ATCO:
PULLERS. Three-jaw pullers 214. Two-jaw pullers 216. Expansion pullers 217. Bar pullers and separators 218. Ball bearing pullers 219
212 Three-jw pullers 214 Two-jw pullers 216 Expnsion pullers 217 Br pullers nd seprtors 218 Bll bering pullers 219 Stud extrctors 221 nd removers Hydrulic jck 221 213 451 N Outside pullers with three jws
VWR CARBOYS. Feature Versatile Cap Technology. Autoclavable. Shape maximizes bench and shelf space
VWR CARBOYS Feature Versatile Cap Technology Autoclavable Shape maximizes bench and shelf space VWR CARBOYS VWR CARBOY WITH VERSATILE CAP TECHNOLOGY VWR s Carboy is an advanced fluid handling system developed
Case 9:13-mj JCL Document 1-1 Filed 09/09/13 Page 1 of 5 AFFIDAVIT IN SUPPORT OF COMPLAINT
Case 9:13-mj-00059-JCL Document 1-1 Filed 09/09/13 Page 1 of 5 1. I, Steven Liss, am a Special Agent (SA) for the Federal Bureau of Investigation, being duly sworn, and state that I am a Special Agent
quick and easy installation guide
www.directdriveopener.com quick and easy installation guide Back 2 Front. Motor Carriage 2. C-rail. Chain. Limit stops. Slide in part (tensioner) Rail assembly Insert C-rail parts () into the connecting
Requirements for pilots for off shore operations
GOVERNMENT OF INDIA OFFICE OF THE DIRECTOR GENERAL OF CIVIL AVIATION TECHNICAL CENTER, OPPOSITE SAFDARJUNG AIRPORT, NEW DELHI CIVIL AVIATION REQUIREMENT SECTION 7-FLIGHT CREW STANDARDS TRAINING AND LICENSING
PBN Navigation Specification
PBN Navigation Specification & TM esign Victor Hernandez RO TM/SR November 2013 Page 1 Navigation Specification, Flight Phase The En route Terminal pproaches: 1. 2. latest rrivals: epartures: continental:
Journal of Air Transport Management
Journl of Air Trnsport Mngement 15 (9) 3 9 Contents lists vilble t ScienceDirect Journl of Air Trnsport Mngement journl homepge: www.elsevier.com/locte/jirtrmn Network competition in the open vition re
QUOTATION REQUEST FORM
QUOTATION REQUEST FORM UNIT PENTADBIRAN FKKSA (PEROLEHAN) FAKULTI KEJURUTERAAN KIMIA DAN SUMBER ASLI UNIVERSITI MALAYSIA PAHANG LEBUHRAYA TUN RAZAK, 26300 KUANTAN, PAHANG. Ref No: UMP/FKKSA/SH/2018(08)
RMT.0464 ATS Requirements The NPA
RMT.0464 ATS Requirements The NPA Fabio GRASSO EASA ATM/ANS Regulations Officer IFISA - FISO Seminar #7 08.09.2016 TE.GEN.00409-001 ATM/ANS CRs Regulation 2016/1377 Main objectives are to: implement Essential
Simple Solutions. Smart Style.
Simple Solutions. Smart Style. 3 Colors Reforms BOTTLENET Innovative and colorful silicone netting, wrap and carry your favorite vino! Expandable bottle tote perfect to carry your wine or to give as a
EASA rulemaking in ATM/ANS. Entry Point North annual AFIS Seminar 5th and 6th of September 2012, Malmö
EASA rulemaking in ATM/ANS Entry Point North annual AFIS Seminar 5th and 6th of September 2012, Malmö Single European Sky II Four pillars of Single European Sky II Single European Sky legislation on ATM»
ECOLABELLING of Portable Rechargeable Batteries
ECOLABELLING of Portable Rechargeable Batteries RECHARGE s APPROACH 1. OBJECTIVE RECHARGE s objective is to contribute to the development of criteria for the Ecolabelling of Portable Rechargeable Batteries
EASA The medium term agenda
EASA The medium term agenda helitech London 25 September 2013 Willy Sigl EASA Outline European aviation rules and roles of involved actors AIR OPS rule structure and rule development Regulation Air OPS
TRAINING BULLETIN #158
TRAINING BULLETIN #158 Quick Clot Combat Gauze And Hemostatic Dressing HEMOSTATIC DRESSING I. Introduction Hemostatic dressings are designed for the control of traumatic exsanguinating external hemorrhage,
Doylestown Community. Pedestrian-Transit Linkage Plan
Doylestown Community Pedestrin-Trnsit Linkge Pln Prepred for: Borough of Doylestown June 2007 Prepred By: Gilmore & Assocites, Inc. 350 E. Butler Avenue New Britin, PA 18901 DOYLESTOWN BOROUGH CULTURAL
effortless sun protection
AWNINGS SHADES CANOPIES effortless sun protection www.betterlivingawnings.com AWNINGS SHADES CANOPIES INNOVATIONS IN SHADE Betterliving offers innovtive solutions, sleek designs nd comfortble shde. With
Atlas Hospitality Hospitality Group 2013 Meet the Money California Hotel Overview May 2013
Atlas Hospitality Group 2013 Meet the Money California Hotel Overview May 2013 Historical Sales Chart #SALES 400 350 300 250 200 150 100 50 0 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011
Period 1 January to 30 June Date Amount (NZ$) Purpose (eg hosting delegation from...) Nature
Chief Executive expenses, gifts and hospitality for the six months to 30 June 2013 Health Research Council of New Zealand Dr Robin Olds, Chief Executive Local Travel Card expenses Period 1 January to 30
ZebMed is a company run by working professional medical staff for medical staff and the general public.
ZebMed is a company run by working professional medical staff for medical staff and the general public. All products have been tested either by Paramedics, EMT's, Doctors or Nurses. One major difference
Volcanic Ash Operations Workshop
Volcanic Ash Operations Workshop John Vincent Deputy Director for Strategic Safety European Aviation Safety Agency EASA 20 January 2011 Cologne Outline Introduction Key activities Yesterday Today Tomorrow
ApL Cohort Aviation Studies (Services Stream) Test on Module AS1 & AS2 Question Paper
ApL 2016-18 Cohort Aviation Studies (Services Stream) Question Paper Name (English FULL Name): Class: Date: Instructions Time Allowed: 1.5 hours Full Mark: 100 1. Candidates should keep silent during the
FIRST AID KITS. HSE 1 Person Kit
FIRST AID KITS HSE 1 Person Kit Ref No : FOR737 CONTENTS 1 x HS1 Green First Aid Box 6 x Assorted Washproof Plasters Sterile 1 x HSE 18x18 Premium Dressing 2 x Triangular Bandage Non Woven 2 x Antiseptic
The Journal of Physiology
J Physiol 593.15 (2015) pp 3333 3350 3333 The role of Ca 2+ influx in spontaneous Ca 2+ wave propagation in interstitial cells of Cajal from the rabbit urethra Bernard T. Drumm 1,2,3, Roddy J. Large 1,MarkA.Hollywood
Interim Policy, FAA Review of Solar Energy System Projects on Federally Obligated Airports
This document is scheduled to be published in the Federal Register on 10/23/2013 and available online at http://federalregister.gov/a/2013-24729, and on FDsys.gov [4910-13] DEPARTMENT OF TRANSPORTATION
HOLY EUROPE TOUR 14 DAYS VISIT ITALY, SWITZERLAND, FRANCE, PORTUGAL AND SPAIN
HOLY EUROPE TOUR 14 DAYS VISIT ITALY, SWITZERLAND, FRANCE, PORTUGAL AND SPAIN Tue-22-May-18 Day 1 Arrive and Transfer to hotel English speaking airport assistant English speaking guide for half day Visit
Part 135 GA Air Operator Certificate Helicopters and Small Aeroplanes General Aviation Helicopters VFR
Part 119 / 135 Compliance Matrix Helicopters VFR General Aviation Air Operator Certificate The rule references in this compliance matrix have been extracted from the Civil Aviation Rules system as the
TH175. Pneumatic Wedge Grips 10, 20, 50, 100 and 300 kn TH Jaws for TH Examples for customized solutions**:
Pneumatic Wedge Grips 10, 20, 50, 100 and 300 kn Self-aligning centric jaw movement Self-intensifying clamping system to hold a sample securely in place Ideal for complicated samples with low coefficient
SERVICE SHEET 34" WALK-BEHIND POWER TROWEL MODEL FT34 (THIS SERVICE SHEET APPLIES TO THE TROWELS WITH SERIAL NUMBER AND AFTER) WARNING
34" WALK-BEHIND POWER TROWEL (THIS APPLIES TO THE TROWELS WITH SERIAL NUMBER 0837 AND AFTER) WARNING To reduce the risk of injury, all operators and maintenance personnel must read and understand these
port vila, vanuatu ALRA Australasian Law Reform Agencies Conference September 2008 Port Vila, Vanuatu
port vil, vnutu LR 2 8 00 ustrlsin Lw Reform gencies Conference 10-12 September 2008 Port Vil, Vnutu S r C Th i L D U Welcome It is with gret plesure tht the University of the South Pcific (USP) invites
THE WARMTH OF WOOD, THE ECONOMY OF PELLETS INNOVATION, TECHNOLOGY, SAVINGS FAIR SRL ITALIAN MADE PELLET STOVES BIO STOVE ADVANTAGES THE PELLET
THE WARMTH OF WOOD, THE ECONOMY OF PELLETS INNOVATION, TECHNOLOGY, SAVINGS FAIR SRL ITALIAN MADE PELLET STOVES With its long-lasting history and many year of experience in the business, today Fair Srl
This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and
This rticle ppered in journl pulished y Elsevier. The ttched copy is furnished to the uthor for internl non-commercil reserch nd eduction use, including for instruction t the uthors institution nd shring
Crown of the Continent Ecosystem The Glacier-Great Bear Connectivity Conservation Area Briefing
Crown of the Continent Ecosystem The Glacier-Great Bear Connectivity Conservation Area Briefing By: Rob Ament & Tyler Creech October 2016 The Glacier-Great Bear Connectivity Conservation Area The Crown
Quad-Lock Container System. sterilization solutions. Symmetry Surgical s Quad-Lock container. system is equipped with a patent-pending,
sterilization solutions Symmetry Surgical s Quad-Lock container system is equipped with a patent-pending, advanced design for dependable lid attachment. Four latches securing the lid Half-size containers
SUMMARY. Document No: Rev: R Tucson, Arizona U.S.A. Cage Code: 0TMJ9 Page 2 of 29 F /12
SUMMARY This Applicability List presents a current listing of components manufactured by Technologies (STI) which have been granted FAA- under Technologies Letter PQ1982NM, Document No: 290-0026- Rev:
High Speed Centrifuge. LHS-A, B Series
High Speed Centrifuge LHS-A, B Series info@labtron.com www.labtron.com High Speed Centrifuge LHS-A10 High Speed Centrifuge LHS-A10 is a microprocessor controlled light weight table top type system with
General Purpose High Power PCB Relays
T9 Series Two-pole 3A PCB or Panel Mount Relay n A, form A (NO) and form C (CO) switching capability n Designed to control compressor loads to 3.5 tons, LRA / 5.3FLA n Meets requirements of UL 58 and UL
REC. Interpretation Guide. Rapid E. coli/coliform Count Plate
Interpretation Guide The M Petrifilm Rapid E. coli/coliform Count Plate is a selective and differential sample-ready-culture medium system which contains proprietary nutrients, a cold-watersoluble gelling
Interpretation Guide. Coliform Count Plate
Interpretation Guide The 3M Petrifilm is a sample-ready-culture medium system which contains modified Violet Red Bile nutrients, a cold-water-soluble gelling agent and a tetrazolium indicator that facilitates
ST. VINCENT AND THE GRENADINES
ST. VINCENT AND THE GRENADINES MARITIME ADMINISTRATION CIRCULAR N SOL 030 Rev. 4 Amendment to the International Convention for the Safety of Life at sea, 1974, as amended. Chapter V Safety of navigation,
Sterilising Department. Buyers Guide.
2013 Sterilising Department Buyers Guide www.cheironhealthcare.com.au Index Index Product Index & Ordering Information 2 PAGE Instrument Cleaning Brushes 3-9 - Reusable Endoscope Cleaning Brushes 10 -
Premium Quality Industrial Knives & Blades
WWW.KNIFE-POINT.CO.UK Premium Quality Industrial Knives & Blades KB1001 0.10mm KB1002 KB1003 KB1004 KB1005 KB1006 KB1007 KB1008 KB1009 KB1010 KB1011 KB1012 Special prod. 0.54mm KB1013 KB1014 KB1015 / 0.50mm
JeppView for Windows. List of pages in this Trip Kit. jep=jeppesen. Trip Kit Index
Trip Kit Index Printed on 28 Jun 2015 Page 1 (c) JEPPESEN SNERSON, IN., 2015, LL RIGHTS RESERVE jep=jeppesen JeppView for Windows List of pages in this Trip Kit Trip Kit Index irport Information For TLPL
NGS Panel Meter Housings Product Drawings Last Updated 7/7/2008
ROS+BOPL NCLOSURS PONIX MCNO COMPNY NGS Panel Meter ousings Product Drawings Last Updated 7/7/200 Rose+Bopla nclosures 7730 xecutive ay Frederick, MD 21704 301-6-900 www.rose-bopla.com rbinfo@pm-usa.com
JeppView for Windows. General Information. Runway Information. Communication Information. jep=jeppesen
irport Information For URMG Printed on 7 Jan 08 Page (c) SNDERSON, INC., 08, LL RIGHTS RESERVED jep= JeppView for Windows General Information Location: GROZNY RUS ICO/IT: URMG / GRV Lat/Long: N4.0', E045
Guidelines for NOTAM Workflow and Allocation of Responsibilities
Guidelines for NOTAM Workflow and Allocation of Responsibilities May 19 2011 INDEX 1- MAIN OBJECTIVES 1 2- ORIGINATION OF NOTAM 1 3- VALUE OF A NOTAM 3 4- DURATION OF NOTAM 4 5- THE AERONAUTICAL DATA CHAIN
The All India Glass Manufacturers Federation
Ref. No. F/164/2011 Dated: 24 th October, 2011 Shri Anand Sharma Hon ble Minister for Commerce and Industry, Govt. of India, Udyog Bhawan, New Delhi Dear Sir, Sub : Provisional Anti-dumping duty (ADD)
GERMANY Opening of the Reichstag in Potsdam Hindenburg Heads (Wmk - Mesh) Hindenburg Heads (Wmk - Swastikas)
GERMANY 1933 - Opening of the Reichstag in Potsdam 6pf deep blue-green 490 398 479 12pf carmine 491 399 480 25pf ultramarine 492 400 481 1933 - Hindenburg Heads (Wmk - Mesh) 3pf bistre-brown 494A 401 482
PHANTOM ML LIGHTED RETRACTOR TUBE SETS ML-2008 & ML-2018
PHANTOM ML LIGHTED RETRACTOR TUBE SETS ML-2008 & ML-208 EXPERIENCE THE DIFFERENCE. EXPERIENCE INNOVATION. Phantom ML Tube Retractor System facilitates minimally invasive exposure and decompression for
See the RAGBRAI Website. This years route will be announced on Jan 21st. The prevailing winds are westerly, or so they say. We don t guarantee it.
RBBC / RAGBRAI FAQ: 1. RAGBRAI XLV? Roman numeral for 45, this year's ride is the 45th crossing of the state, always from west to east, each year starting and ending in a different town. 2. What is the
LADDERS 38 AZOLITE GLASS FIBRE STEP LADDERS
GLASS FIBRE STEP LADDERS P O Box 14168, WADEVILLE, 1422 Azolite Glass Fibre step ladders are of a durable, rugged design. Made of extruded glass fibre, they are extremely light weight, therefore making
UNCLASSIFIED. UNCLASSIFIED Air Force Page 1 of 10 P-1 Line #47
Exhibit P-40, Budget Line Item Justification: PB 2016 Air Force Date: February 2015 3010F: Aircraft Procurement, Air Force / BA 05: Modification of Inservice Aircraft / BSA 5: Other Aircraft ID Code (A=Service
Jesu, Joy of Our Desiring
Jesu, Joy Our Desir $1.00 PDF New Classics eries Jesu, Joy Our Desir or verses piano Johann chop, arr. J.. ach Ed. Chrispher spaas www.aspenhillmic.com 2 Jesu, Joy Our Desir from W 147, Herz und Mund und
LOVE - A CIVIL WAR. Stephen Brown
LOVE - A CIVIL WAR By Stephen Brown 24th March 2008 ste_spike@yahoo.co.uk FADE IN The small white room is filled with aisles of COMPUTERS. SMALL GREY MEN work on each one in total silence. LANNING(early
Flags, wind indicators, self-adhesive flag signals
402 50.50600 Stainless steel table bracket. Set complete with two hooks and 2 hooks holders. 86x52x70h mm. thickness 2 mm. 50.50842 Professional ABS case containing no. 100 different tools. It contains
JeppView for Windows. jep=jeppesen. Trip Kit Index. Printed on 24 Jan 2013 Page 1. List of pages in this Trip Kit. Trip Kit Index
Trip Kit Index Printed on 24 Jan 203 Page (c) SNERSON, INC., 203, LL RIGHTS RESERVE jep= JeppView for Windows List of pages in this Trip Kit Trip Kit Index irport Information For PK Terminal Charts For
Pr oject Summar y. Colonization characteristics of bovine recto-anal junction tissues by Escherichia coli O157:H7
Pr oject Summar y Colonization characteristics of bovine recto-anal junction tissues by Escherichia coli O157:H7 Principal Investigators: James L Bono, Terrance M. Arthur, and Tommy L. Wheeler U.S. Department
Frequently Asked Questions
Frequently Asked Questions Who should attend the tours? People interested in hearing about and seeing the real Mackinac Island will enjoy this tour. Mackinac Revealed is the only source of Island information
Mouth Gag Cheek Retractor Photographic Product Bur Stand Cotton Box / Phial Stand Sterilization Case General Tweezers Instruments Stand Color Tape /
Mouth Gag Cheek Retractor Photographic Product Bur Stand Cotton Box / Phial Stand Sterilization Case General Tweezers Instruments Stand Color Tape / Color Ring Cleaning Brush / ire 190 191 194 197 200
AUTHORITY REQUIREMENTS FOR AIR OPERATIONS
ANNEX II. PART - ARO AUTHORITY REQUIREMENTS FOR AIR OPERATIONS In Annex II to CR - EU N o 965 / 2012, the following points : ARO. OPS. 230, ARO. OPS. 235 and ARO. OPS. 240 are added. Commission Regulation
Marti Donley; Daniel Reese; Rodney White UPC FFY14 TIP AMD pdf
Marti Donley From: Sent: To: Cc: Subject: Attachments: Lloyd Robinson Thursday, October 10, 2013 8:14 AM Andy Waple jason.robinson@vdot.virginia.gov; Marti Donley; Daniel Reese; Rodney White FW: TIP Amendment