ENDOVASCULAR THERAPIES GLOBAL PERIPHERAL PRODUCT CATALOG. Innovating for life.

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1 ENDOVASCULAR THERAPIES GLOBAL PERIPHERAL PRODUCT CATALOG Innovating for life.

2 Table of Contents

3 4 Cristallo Ideale CAROTID SELF -EXPANDING HYBRID STENT SYSTEM 6 Submarine Rapido RX PTA BALLOON CATHETER MO.MA ULTRA PROXIMAL CEREBRAL PROTECTION DEVICE FiberNet EMBOLIC PROTECTION SYSTEM Piton GC CAROTID GUIDE CATHETER Racer RX RENAL STENT SYSTEM Hippocampus RENAL RX STENT SYSTEM Scuba CO-CR PERIPHERAL STENT SYSTEM IN.PACT Admiral PACLITAXEL-ELUTING PTA BALLOON CATHETER Reef HP PTA BALLOON CATHETER OTW Admiral Xtreme PTA BALLOON CATHETER OTW Assurant Cobalt ILIAC BALLOON EXPANDABLE STENT SYSTEM Complete SE Vascular SELF EXPANDING STENT SYSTEM IN.PACT Pacific PACLITAXEL-ELUTING PTA BALLOON CATHETER Pacific Xtreme PTA BALLOON CATHETER Pioneer Plus DIAGNOSTIC ULTRASOUND TRANSDUCER AND PERCUTANEOUS CATHETER Maris Plus PERIPHERAL SELF-EXPANDING STENT SYSTEM IN.PACT Amphirion PACLITAXEL-ELUTING PTA BALLOON CATHETER Amphirion Plus PTA BALLOON CATHETER OTW Amphirion Deep PTA BALLOON CATHETER OTW Chromis Deep INFRAPOPLITEAL BALLOON EXPANDABLE STENT SYSTEM Kitewire Deep PERIPHERAL GUIDEWIRE Maris Deep PERIPHERAL SELF-EXPANDING STENT SYSTEM 0.018

4 Cristallo Ideale CAROTID SELF-EXPANDING HYBRID STENT SYSTEM The 5F HYBRID Stent Deliverable and Secure TECHNICAL SPECIFICATIONS STENT PLATFORM Stent design Stent construction Stent material Wall thickness Multisegment design Slotted tube, laser cut Nitinol 0.16mm DELIVERY SYSTEM Usable shaft length 135cm Recommended guidewire Introducer sheath compatibility Rapid exchange section length 5F 25cm Closed cell area Picture by Dr. Alberto Cremonesi, Cotignola (RA), Italy 4

5 ORDER INFORMATION Stent Ø Stent length Target vessel Ø CRI T / Tapered CRI T / CRI T / CRI T / CRI C CRI C Cylindrical CRI C CRI C CRI C CRI C GW 0.014" 2.82F 5F 135cm 25cm One radiopaque marker positioned inside each end Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 5

6 Submarine Rapido RX PTA BALLOON CATHETER Low Profile with Strength and Control TECHNICAL SPECIFICATIONS Catheter design Balloon material Balloon coating Balloon marker Max. recommended guidewire Nominal pressure Rapid Exchange (RX) FLEXITEC LP Distal shaft and balloon: LFC hydrophilic coating Proximal shaft: PTFE 2 swaged (zero profile) Platinum Iridium (0.46mm) 7 bar COMPLIANCE CHART Pressure (bar) Balloon diameter Balloon length 20, 30 and 40mm Balloon length 60 and 80mm Nominal pressure Rated Burst Pressure 6

7 ORDER INFORMATION shaft length 135 cm Balloon diameter Balloon length RBP (bar) Usable shaft length (cm) Guiding catheter compatibility (F) Distal shaft Ø (F) SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR SBR Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 7

8 MO.MA ULTRA PROXIMAL CEREBRAL PROTECTION DEVICE Full-Time Protection and Control TECHNICAL SPECIFICATIONS Balloon material Balloon marker distance Compliant elastomeric rubber 6cm* Distal shaft profile 5F* Recommended guidewire Balloon occlusion range (0.89mm) Up to 13mm (CCA prox. balloon) Up to 6mm* (ECA dist. balloon) * (Double-Balloon only) DOUBLE-OCCLUSION BALLOON SYSTEM* Utilizes highly-compliant, elastomeric balloons that provide atraumatic flow suspension and stability MONO-OCCLUSION BALLOON SYSTEM In case of occlusion of the external carotid artery (ECA), the system utilizes one highlycompliant, elastomeric balloon in the common carotid artery (CCA), that provides atraumatic flow suspension and stability 8 *Bench test data on file at Medtronic, Inc. Test data not indicative of clinical performance.

9 ORDER INFORMATION Double-Balloon Minimum sheath size Inner Ø of the working channel MOM X5 8F / 1.76mm MOM X6 9F / 2.12mm 1045mm 60 mm 950 mm Mono-Balloon Minimum sheath size Inner Ø of the working channel MOM X5 8F / 1.76mm 1050mm 900mm All sizes of debris will be captured Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 9

10 FiberNet EMBOLIC PROTECTION SYSTEM Performance through Design * TECHNICAL SPECIFICATIONS Indication Filter material Wire length Deployed filter length Delivery method Particle capture size Recovery method Catheter length Carotid PET fibers 190cm 9.5mm No delivery system required 40 μm Rapid exchange retrieval aspiration catheter 150cm CONFORMABILITY The FiberNet (EPS) filter provides 360 degrees of atraumatic apposition and stability, minimizing vasospasm. CAPTURABILITY FiberNet (EPS) captures particles as small as 40 microns, potentially reducing embolic events. CONTAINABILITY The unique 3-D fiber matrix of FiberNet (EPS) contains embolic particles, allowing for efficient aspiration and removal. 10 *Bench test data on file at Medtronic, Inc. Test data not indicative of clinical performance.

11 ORDER INFORMATION Vessel Size Crossing Profile 1 Minimum F Guide/Sheath Minimum ID of Guide/Sheath 2 FBN F 6F / 6F 0.070" FBN F 7F / 6F 0.079" FBN F 7F / 6F 0.079" 1 FiberNet filter (nominal) 2 Compatible with aspirations/retrieval catheter RADIOPAQUE MARKER BANDS CONFIRM FILTER DEPLOYMENT DELIVERABILITY Low profile guidewirebased system enables FiberNet (EPS) deliverability through tortuous anatomies and complex lesions. RETRIEVAL Integrated Aspiration and Retrieval The FiberNet (EPS) is retrieved through a Retrieval/Aspiration Catheter. Aspiration enables capture and containment of embolic particles during filter retrieval. Manufactured by Lumen Biomedical Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 11

12 Piton GC CAROTID GUIDE CATHETER Accessing the Future of CAS Intervention TECHNICAL SPECIFICATIONS Outer diameter Inner diameter Total catheter length Usable catheter length 8F (0.104 / 2.64mm) 5F (0.073 / 1.86mm) 91cm 85cm Guidewire outer diameter max. 2 x

13 ORDER INFORMATION Usable length (cm) Tip curve PTN8SC cm Small 91cm 85cm Side hole 8F 0.063" (1.60mm) 0.085" (2.16mm) i b l e C o i l l e x F Side hole Braid Marker Band Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 13

14 Racer RX RENAL STENT SYSTEM Flexibility to Get You There. Strength to Keep You There. TECHNICAL SPECIFICATIONS STENT PLATFORM Stent design Stent construction Stent material Delivery system marker Modular LASER fused sinuscoidal elements Cobalt Chromium Gold material Strut thickness 145µm DELIVERY SYSTEM Catheter length 80 and 130cm Recommended guidewire Introducer sheath compatibility 5F (Ø4-6mm), 6F (Ø7mm) Our patented Secure Technology stent retention system features distal and proximal pillows that offer added security during delivery. Smaller cell area is designed to better conform to the vessel wall and help minimize tissue prolapse 14

15 ORDER INFORMATION IN./0.36-MM RAPID-EXCHANGE PLATFORM Stent Diameter 12 (80 cm shaft) Stent Length 12 (130 cm shaft) 18 (80 cm shaft) 18 (130 cm shaft) Minimum Sheath I.D. (F/mm/in.) Minimum Guide I.D. (F/mm/in.) 4 RCR412XS RCR412XL RCR418XS RCR418XL 5/1.67/ /1.68/ RCR512XS RCR512XL RCR518XS RCR518XL 5/1.67/ /1.68/ RCR612XS RCR612XL RCR618XS RCR618XL 5/1.67/ /1.68/ RCR712XS RCR712XL RCR718XS RCR718XL 6/2.00/ /1.90/0.076 COMPLIANCE CHART IN./0.36-MM COMPLIANCE Pressure Deployed Stent I.D. (kpa) (atm) Nominal pressure Rated burst pressure Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 15

16 Hippocampus RENAL RX STENT SYSTEM Dedicated to Renal Artery Treatment TECHNICAL SPECIFICATIONS STENT Stent design Stent material Stent diameter Stent length Strut thickness / width Closed cell Stainless Steel 4.0, 5.0, 5.5, 6.0, 6.5, 7.0mm 10, 15, 20, 24mm 165 / 110μm STENT DELIVERY SYSTEM Catheter design RX (Rapid Exchange) Shaft diameter prox./dist. 2.3F / 3.5F Usable shaft length 80 and 145cm Recommended guidewire Introducer sheath compatibility 5F Guiding catheter compatibility 6F (> ) Nominal Pressure 8 bar Ostial Scaffolding Progressive flexibility Closed cell design with proximal, ostial flaring capability 16

17 ORDER INFORMATION Usable length 80 cm Usable length 145 cm Stent inner Ø Stent length RBP (bar) IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP IHP RX section, 15cm 2 Distal shaft diameter 3.5F 3 Proximal shaft diameter 2.3F Stent length 5 Stent diameter 6 Usable shaft length Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 17

18 Scuba CO-CR PERIPHERAL STENT SYSTEM Innovative Stent Design with Flexibility and Strength TECHNICAL SPECIFICATIONS STENT Stent design Stent material Stent diameter Stent length Strut thickness Laser slotted, closed cell Cobalt Chromium 5.0, 6.0, 7.0, 8.0, 9.0, 10.0mm 18, 30, 37, 55, 75mm 120μm (Ø 5 7mm), 152μm (Ø 8 10mm) STENT DELIVERY SYSTEM Catheter design Shaft diameter Usable shaft length Over the Wire (OTW), dual lumen shaft 5F 80 and 130cm Guidewire compatibility Balloon material FLEXITEC Xtreme Closed cell design 6-fold balloon 18

19 ORDER INFORMATION Usable length 80 cm Usable length 130 cm Stent inner Ø Stent length Recom. introducer sheath (F) NBP (bar) SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA SCA RBP (bar) 1 Stent inner diameter 2 Stent nominal length 3 Shaft diameter 4 Usable shaft length Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 19

20 IN.PACT Admiral PACLITAXEL-ELUTING PTA BALLOON CATHETER (0.035 ) Opening a Novel Path to Success TECHNICAL SPECIFICATIONS Catheter design Balloon material Balloon coating Usable shaft lengths Shaft diameter Introducer sheath compatibility Over the Wire (OTW) FLEXITEC Xtreme FreePac Paclitaxel and Urea (excipient) 80 and 130cm 5F 5F-6F-7F Max. recommended guidewire Nominal pressure 8 atm IMPROVING OUTCOMES AND OPTIONS Numerous trials demonstrating favorable results Leaving nothing behind in vessel provides significant benefits for physicians and patients OPTIMIZED AND TRUSTED TECHNOLOGY Proven balloon platform backed by Invatec legacy of innovation Demonstrated efficacy and safety in both clinical and pre-clinical settings LEADING THE WAY IN EVIDENCE CREATION Most robust clinical data available today with consistent favorable results in both SFA and BTK Most robust clinical program with over 29 trials and 4,600 patients under study Paclitaxel is carried across the vessel wall by the urea Paclitaxel - Proven Antiproliferative Urea - Natural and Hydrophilic Excipient 20

21 ORDER INFORMATION Usable length 80 cm Usable length 130 cm Balloon Ø Balloon length Recom. introducer sheath (F) Markers RBP (atm) SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P SBI P Balloon nominal diameter Balloon nominal length Shaft diameter Usable shaft length Balloon Lengths 40mm 60mm 80mm 120mm Balloon Diameters 4, 5, 6, 7mm Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 21

22 Reef HP PTA BALLOON CATHETER OTW TECHNICAL SPECIFICATIONS Catheter design Balloon material Balloon marker Usable shaft lengths Shaft diameter Introducer sheath compatibility Nominal pressure Over the wire (OTW) Flexitec XF 2 swaged (zero profi le) Platinum Iridium 50, 80 and 120cm 5 F 5F 7F 10 bar Guidewire compatibility REEF HP: Low-compliant angioplasty STANDARD PTA BALLOON: Semi-compliant angioplasty Shape retention Uniform dilating force Dog bone effect Less dilating force at lesion Risk of dissection at the balloon edges 22

23 ORDER INFORMATION Ref N 50 cm shaft length Ref N 80 cm shaft length Ref N 120 cm shaft length Balloon diameter Balloon length RBP (bar) Introducer sheath compatibility (F) REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU REU Balloon nominal diameter 2 Balloon nominal length 3 Shaft diameter 4 Usable shaft length Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 23

24 Admiral Xtreme PTA BALLOON CATHETER OTW Cross Lesions with Confidence TECHNICAL SPECIFICATIONS Catheter design Over the Wire (OTW) Balloon material Flexitec Xtreme Balloon coating LFC Hydrophilic Balloon marker 2 swaged (zero profile) Platinum Iridium Shaft diameter 5F 6F Usable shaft lengths 80 and 130cm Introducer sheath compatility 5F 7F Guidewire compatibility Balloon nominal diameter Balloon nominal length Shaft diameter Usable shaft length Length

25 ORDER INFORMATION Usable length 80 cm Usable length 130 cm Balloon Ø Balloon length Recom. introducer sheath (F) SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI SBI Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice RBP (bar) 25

26 Assurant Cobalt ILIAC BALLOON EXPANDABLE STENT SYSTEM Best in Class for Profile, Flexibility and Conformability TECHNICAL SPECIFICATIONS STENT PLATFORM Stent design Stent construction Stent material Delivery system marker Modular LASER fused sinuscoidal elements Cobalt Chromium Gold material Strut thickness 172µm DELIVERY SYSTEM Catheter length 80 and 130cm Recommended guidewire 0.035" Introducer sheath compatibility 6F 26

27 ORDER INFORMATION Stent Diam. Stent Length Catheter Length (cm) Minimum Sheath/Guide Compatibility 6 ASC620S ASC620L ASC630S ASC630L ASC640S ASC660S F 7 ASC720S ASC720L ASC730S ASC730L ASC740S ASC760S F 8 ASC820S ASC820L ASC830S ASC830L ASC840S ASC860S F 9 ASC930S ASC930L ASC940S ASC960S F 10 ASC1030S ASC1030L ASC1040S ASC1060S F COMPLIANCE CHART Pressure (atm) (kpa) Deployed Stent I.D Nominal pressure Rated burst pressure (do not exceed) The Assurant Cobalt iliac stent system is compatible with a maximum guidewire of in. Cobalt-chromium-alloy composition allows for immediate postprocedure MRI imaging (MRI conditional). Modular design allows for superior conformability compared with the Cordis Palmaz Genesis stent and the Boston Scientific Express LD stent.* * Bench data on file at Medtronic, Inc., compares the Assurant Cobalt stent with the Cordis Palmaz Genesis stent and the Boston Scientific Express LD stent. Bench test results may not be indicative of clinical performance. Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 27

28 Complete SE Vascular SELF EXPANDING STENT SYSTEM Complete Performance Control. Commitment. Confidence. TECHNICAL SPECIFICATIONS STENT PLATFORM Stent design Stent construction Stent material Stent marker Strut thickness Multisegmented LASER cut tube NiTi (Nitinol) 4 each end ~190µm DELIVERY SYSTEM Catheter length 80 and 130cm Recommended guidewire 0.035" Introducer sheath compatibility 6F TLR rate 8.4% at 12 months * * Reference Complete SE SFA Study - Clinically Driven TLR rate. 28 The Complete SE Vascular Stent System may not be approved for the Iliac and SFA/PPA indications in all countries

29 ORDER INFORMATION Stent Diam. Stent Length Min. Sheath Size (F) Catheter Working Length (cm) 4 SC420LG SC430LG SC440LG SC520LG SC530LG SC540LG SC560LG SC580LG SC5100LG SC5120LG SC5150LG SC620LG SC640LG SC660LG SC680LG SC6100LG SC6120LG SC6150LG SC720LG SC740LG SC760LG SC780LG SC7100LG SC7120LG SC7150LG SC820LG SC840LG SC860LG SC880LG SC8100LG SC8120LG SC8150LG SC920LG SC940LG SC960LG SC980LG SC1020LG SC1040LG SC1060LG SC1080LG Stent Diam. Stent Length Min. Sheath Size (F) Catheter Working Length (cm) 4 SC420FG SC430FG SC440FG SC520FG SC530FG SC540FG SC560FG SC580FG SC5100FG SC5120FG SC5150FG SC620FG SC640FG SC660FG SC680FG SC6100FG SC6120FG SC6150FG SC720FG SC740FG SC760FG SC780FG SC7100FG SC7120FG SC7150FG SC820FG SC840FG SC860FG SC880FG SC8100FG SC8120FG SC8150FG SC920FG SC940FG SC960FG SC980FG SC1020FG SC1040FG SC1060FG SC1080FG 6 80 Dual-deployment handle Atraumatic tip Stabilizing sheath Retractable sheath Radiopaque markers Retractable sheath Inner shaft The stabilising sheath reduces friction and allows the retractable sheath to move back freely. This decreases the amount of force required to deploy the stent, making deployment easy and accurate. Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 29

30 IN.PACT Pacific PACLITAXEL ELUTING PTA BALLOON CATHETER (0.018 ) Opening a Novel Path to Success TECHNICAL SPECIFICATIONS Catheter design Balloon material Balloon coating Usable shaft lengths Over the Wire (OTW), coaxial shaft Flexitec Xtreme FreePac Paclitaxel and Urea (excipient) 90 and 130cm Shaft diameter 3.9F Introducer sheath compatibility 5F 6F Guidewire compatibility 0.018" Nominal pressure 7 bar IMPROVING OUTCOMES AND OPTIONS Numerous trials demonstrating favorable results Leaving nothing behind in vessel provides significant benefits for physicians and patients OPTIMIZED AND TRUSTED TECHNOLOGY Proven balloon platform backed by Invatec legacy of innovation Demonstrated efficacy and safety in both clinical and pre-clinical settings LEADING THE WAY IN EVIDENCE CREATION Most robust clinical data available today with consistent favorable results in both SFA and BTK Most robust clinical program with over 29 trials and 4,600 patients under study Paclitaxel is carried across the vessel wall by the urea Paclitaxel - Proven Antiproliferative Urea - Natural and Hydrophilic Excipient 30

31 ORDER INFORMATION Usable length 90 cm Usable length 130 cm Balloon Ø Balloon length Recom. introducer sheath (F) PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P PCF P RBP (bar) Balloon nominal diameter Balloon nominal length Shaft diameter Usable shaft length Balloon Lengths 40mm 60mm 80mm 120mm Balloon Diameters 4, 5, 6, 7mm Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 31

32 Pacific Xtreme PTA BALLOON CATHETER Versatility for Everyday and Beyond TECHNICAL SPECIFICATIONS Catheter design Balloon material Balloon coating Balloon marker Over the wire (OTW), coaxial shaft Flexitec Xtreme LFC Hydrophilic 2 swaged, Platinum Iridium Shaft diameter 3.9F 4.2F Usable shaft lengths 90, 130, 180cm Guidewire compatibility

33 ORDER INFORMATION Usable length 90cm Usable length 130cm Usable length 180cm Balloon Ø Balloon length Recom. introducer sheath (F) Nominal pressure (bar) PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF PCF RBP (bar) Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 33

34 Pioneer Plus DIAGNOSTIC ULTRASOUND TRANSDUCER AND PERCUTANEOUS CATHETER Visualise Success TECHNICAL INFORMATION Sheath compatibility 6 F (0.087", 2.2 mm) Tracking guidewire 0.014" Needle guidewire 0.014" Catheter length 120 cm 34

35 ORDER INFORMATION Product Name Pioneer Plus Catheter Product Code PPLUS120 True lumen with ChromaFlo feature Intima Pioneer Plus catheter in subintimal space Adventitia Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 35

36 Maris Plus PERIPHERAL SELF EXPANDING STENT SYSTEM Tailor Your Stent to the Lesion TECHNICAL SPECIFICATIONS STENT Stent design Stent material Stent diameter Stent length Marker STENT DELIVERY SYSTEM Laser cut, multisegmented Nitinol 6, 7, 8, 9, 10, 12mm 30, 40, 60, 80, 100, 120, 150mm 2 Tantalum stent markers, fully integrated Catheter design Over the wire (OTW) Introducer sheath compatibility 6F Usable shaft length 80 and 120cm Guidewire compatibility Conformable stent design Exclusive stent overlap region 36

37 ORDER INFORMATION Ref N 30 mm stent length Ref N 40 mm stent length Ref N 60 mm stent length Ref N 80 mm stent length Stent Ø Shaft length (cm) Recom. vessel Ø MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP Ref N 100 mm stent length Ref N 120 mm stent length Ref N 150 mm stent length Stent Ø Shaft length (cm) Recom. vessel Ø MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP MRP F Luer Slider* Handle Luer 80cm / 120cm Stent length Stent diameter Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 37

38 IN.PACT Amphirion PACLITAXEL ELUTING PTA BALLOON CATHETER (0.014 ) Opening a Novel Path to Success TECHNICAL SPECIFICATIONS Catheter design Balloon material Balloon coating Usable shaft lengths Shaft diameter Introducer sheath compatibility Over the Wire (OTW) FLEXITEC Ultra FreePac Paclitaxel and Urea (excipient) 120 and 150cm proximal 3.3F for 120cm shaft length 3.9F for 150 m shaft length middle 3.3F distal 2.8F 4F Max. recom. guidewire Nominal pressure 7 bar IMPROVING OUTCOMES AND OPTIONS Numerous trials demonstrating favorable results Leaving nothing behind in vessel provides significant benefits for physicians and patients Paclitaxel is carried across the vessel wall by the urea OPTIMIZED AND TRUSTED TECHNOLOGY Proven balloon platform backed by Invatec legacy of innovation Demonstrated efficacy and safety in both clinical and pre-clinical settings LEADING THE WAY IN EVIDENCE CREATION Most robust clinical data available today with consistent favorable results in both SFA and BTK Most robust clinical program with over 29 trials and 4,600 patients under study Paclitaxel - Proven Antiproliferative Urea - Natural and Hydrophilic Excipient 38

39 ORDER INFORMATION Usable length 120 cm Usable length 150 cm Balloon Ø Balloon length Recom. introducer sheath (F) AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P AMD P RBP (bar) Usable shaft length 5 Balloon inflation port Guidewire port Kink protection Balloon length 5 Balloon diameter Balloon Lengths 40mm 80mm 120mm Balloon Diameters 2.0, 2.5, 3.0, 3.5, 4.0mm Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 39

40 Amphirion Plus PTA BALLOON CATHETER OTW Take a Step Forward TECHNICAL SPECIFICATIONS Catheter design Balloon coating Over the Wire (OTW) Balloon and distal shaft LFC hydrophilic Shaft diameter proximal 4F / distal 2.9F Max. recommended guidewire 0.014" Minimum sheath inner diameter Nominal Pressure 4F 10 bar Usable shaft length Balloon inflation port Guidewire port Kink protection Balloon length Balloon diameter Distal balloon diameter Proximal balloon diameter Above the Ankle 40

41 ORDER INFORMATION Usable length 100 cm Usable length 150 cm Balloon Ø Balloon Length AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP AHP COMPLIANCE CHART (Amphirion Plus up to 120mm ballon length) bar Balloon Diameter in vitro results 2 Do not exceed RBP Nominal Pressure Rated Burst Pressure 2 Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 41

42 Amphirion Deep PTA BALLOON CATHETER OTW Take a Step Forward TECHNICAL SPECIFICATIONS Catheter design Balloon material Balloon coating Shaft diameter Over the Wire (OTW) FLEXITEC Ultra Balloon and distal shaft LFC hydrophilic proximal 3.9F, middle 3.3F / distal 2.8F/2.6F Max. recommended guidewire 0.014" Introducer sheath compatibility Nominal Pressure 4F 7 bar Below the Ankle Image courtesy of Dr. Marco Manzi, Italy. 42

43 ORDER INFORMATION Usable length 120 cm Usable length 150 cm Balloon Ø Balloon Length AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD AMD / AMD AMD / AMD AMD / AMD AMD / Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 43

44 Amphirion Deep PTA CATHETER OTW COMPLIANCE CHART (Amphirion Deep up to 150mm balloon length) Pressure (atm) Balloon Diameter Nominal Pressure Rated Burst Pressure 2 COMPLIANCE CHART (Amphirion Deep 210mm tapered balloon length) Pressure (atm) Distal 2.50 Prox 2.50 Distal 2.50 Balloon Diameter 1 Prox 3.00 Distal 3.00 Prox 3.50 Distal Nominal Pressure Rated Burst Pressure 2 1 in vitro results 2 Do not exceed RBP Prox

45 Usable shaft length Balloon inflation port Guidewire port Kink protection Balloon length Balloon diameter Distal balloon diameter Proximal balloon diameter 210mm Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 45

46 Chromis Deep INFRAPOPLITEAL BALLOON-EXPANDABLE STENT SYSTEM Dedicated Infrapopliteal Co-Cr Stent TECHNICAL SPECIFICATIONS STENT Stent construction Stent material Stent diameter Stent length Strut thickness/width Slotted tube, laser cut Cobalt chromium 2.0, 2.5, 3.0, 3.5, 4.0 mm 10, 18, 38, 57, 76 mm 70/75 µm ( mm) 80/75 µm ( mm), 95/85 µm (4.0 mm) STENT DELIVERY SYSTEM Catheter design Usable shaft length Guidewire compatibility Introducer sheath compatibility Marker Over the Wire (OTW) 120 and 150 cm 0.014" (0.36 mm) 4 F 2 swaged (zero profile) platinum iridium DEDICATED INFRAPOPLITEAL CO-CR STENT SMALL VESSEL SV Diameter: mm Strut thickness: 70 μm Number of circumferential cells: 3 MEDIUM VESSEL MV Diameter: mm Strut thickness: 80 μm Number of circumferential cells: 4 LARGE VESSEL LV Diameter: 4.0 mm Strut thickness: 95 μm Number of circumferential cells: 5 46

47 ORDER INFORMATION Usable Length 120 cm Usable Length 150 cm Stent Ø Stent Length CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD CRD RBP (bar) Stent nominal inner diameter Stent nominal length 3 4 Distal shaft diameter 2.8 F Middle shaft diameter 3.3 F 5 Proximal shaft diameter 3.9 F for 150 cm shaft 3.3 F for 120 cm shaft 6 Usable shaft length Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 47

48 Kitewire Deep PERIPHERAL GUIDEWIRE Smooth Trackability for Long Diffuse BtK Vessels TECHNICAL SPECIFICATIONS Guidewire outer diameter 0.014" Coating of the guidewire coil Total length of the guidewire Support Radiopaque coil length Tip shape Tip stiffness variations Polymer and hydrophilic 195, 250 and 300 cm Extra support 3 cm platinum alloy spring coil Straight, shapable Standard and intermediate 48 MANUFACTURER: Brivant Ltd, Parkmore West Business Park, Galway, Ireland

49 ORDER INFORMATION Usable Length (cm) Tip Stiffness KTD 195 INT 14S 195 Intermediate KTD 195 STD 14S 195 Standard KTD 250 INT 14S 250 Intermediate KTD 250 STD 14S 250 Standard KTD 300 INT 14S 300 Intermediate KTD 300 STD 14S 300 Standard Outer diameter 2 Platinum coil 3 Polymer jacket 4 Stainless steel body 5 Usable length Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 49

50 Maris Deep PERIPHERAL SELF-EXPANDING STENT SYSTEM Go Deep with Our Smallest Self-Expanding Stent System TECHNICAL SPECIFICATIONS STENT Stent design Stent material Stent diameter unconstrained Stent length unconstrained Marker Laser cut, multisegmented Nitinol 3.0, 4.0, 5.0, 6.0 mm 20, 40, 60, 80 mm 2 Tantalum stent markers STENT DELIVERY SYSTEM Catheter design Usable shaft length Over the Wire (OTW) 90 and 130 cm Guidewire compatibility Introducer sheath compatibility 4 F Two fully integrated stent markers Dedicated highly flexible stent platform 50

51 ORDER INFORMATION Usable Length 90 cm Usable Length 130 cm Stent Ø Stent Length Recom. Vessel Ø MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD MRD Stent nominal length 2 Stent unconstrained diameter 1 3 Shaft outer diameter 3.7 F 4 Usable shaft length Under continuous product development program, Medtronic reserves the right to modify specifications without prior notice 51

52 Invatec S.p.A. Via Martiri della Libertà Roncadelle (BS) Italy Tel: Medtronic of Canada Ltd. 99 Hereford Street Brampton, Ontario L6Y 0R3 Canada Tel: Medtronic Korea Co., Ltd. 5F, Sajo Building 1001 Daechi-dong, Kangnam-ku Seoul, Korea Tel: INVATEC Technology Center GmbH Hungerbüelstrasse 12a 8500 Frauenfeld Switzerland Tel: Medtronic Latin America 3750 NW 87th Avenue, Suite 700 Miami, FL USA Tel: Medtronic Mediterranean S.A.L. St. Charles City Center 6th Floor, Omar Doauk Street Beirut Lebanon Tel: Medtronic, Inc. 710 Medtronic Parkway NE Minneapolis, MN USA Tel: Medtronic International Ltd. 49 Changi South Avenue 2 Singapore Tel: Medtronic International Trading Sàrl Route du Molliau 31 CH-1131 Tolochenaz Switzerland Tel: Medtronic Australasia Pty Ltd. 97 Waterloo Road North Ryde, NSW 2113 Australia Tel: UC EE Medtronic, Inc All rights reserved. Printed in Europe. Not for distribution in the USA. 12/12

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