3. Example of GPS Activities on Website Uploaded GSSs on the company website
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1 3. Example of GPS Activities on Website Uploaded GSSs on the company website GPS Safety Summary Page on BASF Website summaries.basf.com/group/corporate/safety summaries/en/?indexterm=b 1 1
2 Example: GPS promotion site on Cefic website 2 Conversion template REACH dossier into GPS Safety Summary 13 June
3 4. JCIA BIGDr 3 BIGDr (read as Big Doctor ) The Base of Information Gathering, sharing & Dissemination for risk management of chemical products Integrated Portal Web System for supporting & promoting Japanese GPS/JIPS activity Gathering Hazard & Exposure Information Risk Assessment Creation of GSS Dissemination of GSS Integrating external links rather than having its own contents user friendly One stop service (Most of necessary information can be obtained) developed and operated by JCIA and Mizuho Information & Research Institute
4 JCIA BIGDr 4 Updating history 2013/08 v1.0 Launched (JCIA members limited: ID/PW required) continue to revise for function expansion 2015/04 v2.3 (latest) (GSS uploading records, Hazard Information DB Search GHS classification regulatory information GSS Maker) 2015/02 v2.2+ Released: most functions opened to the General Public (Exclusion: GSS Maker, Seminar materials, etc.) At present 500 access/day,comparedwith20 50 access before open action GSS Maker (English version) released (2015/04) Development Plan JCIA BIGDr (English version) is currently under discussion.
5 JCIA BIGDr Access 5 JCIA Website 1 (2 Links into BIGDr Page) 2 Access to page of BIGDr bigdr.jp 1
6 JCIA BIGDr Top Page 6 Block-2 Block-4 JCIA BIGDr Ver2.3 April, 2015 Hazard info. DBs Portal GSS uploading records Regulation info. DBsPortal of Japanese company Link list GPS/JIPS Helpdesk Block-1 How to use BIGDr Block-3 Risk assessment & GSS creation tool GSS Maker RA support contents (Seminar Materials etc.) Block-5 General Info. Gathering Chemi-maga
7 JCIA BIGDr (1) Hazard info. DB Portal (1/3) 7 Substance Search Menu Search by the Substance Name or CAS Number Choose output format between a List format and Matrix format Top Page Block-2 Hazard info. DBs Portal Search Substance Name Output Format (List or Matrix) CAS Number Federated Search onto typical hazard information DB, including most of famous Japanese DB. Jump directly to the source of hazard information in the corresponding external DB by one click.
8 JCIA BIGDr (1) Hazard info. DB Portal (2/3) 8 Search Results Example: Formaldehyde(CAS ) List format Matrix format Click here, then you can jump to the corresponding source data & information Formaldehyde/ CHRIP
9 JCIA BIGDr (1) Hazard info. DB Portal (3/3) 9 External DB to be federated search by JCIA BIGDr Ver.2.3 DB Establish NB Substance GHS (Japan) NITE Japanese Government (MHLW, METI, MOE) [ 2,886 GHS (EU) EU EU CLP (Annex Ⅵ) 3,905 GHS (Korea) NIER Korea GHS Classification 781 GPS Chemicals Portal ICCA GPS Safety Summary of Japanese Company - CHRIP NITE Hazard, Risk assessment & Regulatory information 9,000 Nikkaji Web JST Japan Chemical Substance Dictionary Web service; from literature 210,000 WebKis-Plus NIES Use, production volume, exposure, risk assessment and accident 7,000 SDS/ OHSL MHLW Model SDS based on GHS 2,711 GHS/ OHSL MHLW Model label based on GHS 2,218 JECDB MHLW/NIHS Repeated dose toxicity, reproductive and developmental toxicity, mutagenicity, etc. of existing chemical substances Chemical Products Information DB JCIA Component, composition, use and hazard and contact information of chemical products by chemical companies SIDS (environmental) MOE Screening risk assessment report of Chemical Substance 371 SIDS (Japan) NITE/CERI Screening risk assessment report of PRTR Substance 265 SIDS (OECD) OECD SIAR of Chemical Substance 1, ,899
10 JCIA BIGDr (2) GSS uploading records (1/2) 10 GSS Uploading Records Top Page Substance Name List Company Name List Block-4 GSS uploading records of Japanese company Link list of all uploaded GSS of Japanese companies Substance Name List and Company Name List Update on a monthly As of March 2015, 382 GSSs have been recorded PDF of GSS opens in one click
11 JCIA BIGDr (2) GSS uploading records (2/2) 11 Substance name CAS # Company name & Link Substance Name List PDF of GSS uploaded onto ICCA Chemicals Portal or company website will open directly. Opened GSS You can efficiently review all GSSs uploaded from Japanese companies within "GSS Uploading Records" of JCIA BIGDr.
12 JCIA BIGDr (3) GSS Maker (1/6) RA & GSS creation support tool GSS Maker The GSS Maker provides an easy to understand interface to perform risk assessment by using ECETOC TRA and to create GSS semi automatically inputting/outputting onto Excel sheet in Japanese or English. At Present offered only to JCIA members Block-3 GSS Maker 12 User ID Password Log in GSS Maker Excel File (Japanese Version) (English Version) Download "GSS Maker" Excel file from this Link Input User ID and Password Click on Login button Download "ECETOC TRA" Excel file from the ECETOC Website
13 JCIA BIGDr (3) GSS Maker (2/6) 13 GSS Maker is a Wrapping Program, running ECETOC TRA in the background GSS Maker (Excel, Japanese/English) Main Unit Setting parameters, Run button, Display of RC Results by ECETOC TRA GSS Unit Output of GSS DB Unit Data table of target substance, Correspondence table RC results and GSS ECETOC TRA (Excel, English) Run Risk Characterization by posting parameters to ECETOC TRA Extract only necessary result of RC and Create GSS semi automatically
14 JCIA BIGDr (3) GSS Maker (3/6) 14 Configuration Sheet (0) Enter the address of ECETOC TRA file Main Check Scenario Check Scenario Sheet A Trial case of Toluene has been prepared in order to understand how to use the GSS Maker. Practice doing RA and creating GSS by varying parameters Configuration Substance DB
15 JCIA BIGDr (3) GSS Maker (4/6) 15 STEP(1) Identification of Substance Substance Name STEP(1) Identification of Substance Toluene CAS Registry No. Parameter TIER I-simplified TIER I-normal STEP(2) Physical-chemical properties and indicative reference values Help STEP(2) Properties & Reference Values *Read substance info from data base (for manual entry via interface 'Manual entry' ) Substance info from data Manual entry base Molecular weight g/mol Help TIER II Main Sheet (1) Input Substance name Select Tier mode Water solubility Physical-chemical properties Water solubility Measurement Conditions (at C) Reference values Worker Assessment(e.g. DNEL, OEL, ) Consumer Assessment(e.g. DNEL, OEL, ). Environmental Assessment (PNEC,DNEL) Vapour pressure Pa 3000 Vapour pressure Measurement Conditions (at C) Biodegradability test result - Partition coefficient organic carbonwater L.kg-1 Freshwater sediment C mg/l C Partition coefficient octanol-water logkow 2.65E+00 long-term inhalation (8-hour average) long-term dermal inhalation dermal oral Microorganisms in STP mg.m-3 mg kg-1 day-1 mg.m-3 mg kg-1 day-1 mg kg-1 day-1 mg L-1 Freshwater aquatic mg L-1 Marine water aquatic mg L-1 Marine sediment mg kgdwt-1 readily biodegradable E mg kgdwt (2) Input physicalchemical properties, Reference values (If you want to edit the default values, input directly into Cells in light blue) Terrestrial compartment mg kgdwt Man via the environment (total daily intake) mg kgbw-1 d
16 JCIA BIGDr (3) GSS Maker (5/6) 16 STEP(3) Entry of Scenarios Main Sheet (3) Input exposure scenario (workers, consumers, environmental) (Yellow cell) (4-1) Run risk characterization (ECETOC TRA) (4-2) Check results (Pink cell) (RCR <1) STEP(4) Run & output of Results (4-3) Create GSS automatically (GSS can only be created, if RCR <1 in all exposure scenario)
17 JCIA BIGDr (3) GSS Maker (6/6) 17 Creation of GSS Check RCR<1 in all exposure scenarios Click on the "Create GSS" button To generate automatically the corresponding GSS as an Excel file To edit it as needed later
18 JCIA BIGDr for supporting GPS implementation 18 How to proceed GPS? Link list to Hazard Info. Hazard Info. DB Portal Regulation Info. DB Portal DB Link Helpdesk (JCIA) Hazard Hazard Info. DB Portal Link list to Hazard Info. Regulation Regulation Info. Link list to Regulation Info. Exposure Maintenance (Mizuho) Archive Chemi maga Link list to Exposure Info. Expert Information to the Supply chain Helpdesk Risk Assessment Tool Link list to Exposure RA Tool Risk Assess. Risk Manage. Risk Assessment Practice RA Support Contents GSS Link list to Hazard GSS uploading Records Link list Link Dissemination GSS uploaded onto ICCA GPS Portal Risk Assessment Practice GSS Maker Risk Assessment & GSS Creation Tool
19 5. Conclusion 19 GPS provides transparent access to science-based product safety information for the public and throughout the value chain. Check the contents / quality of GSS before dissemination. Referring to examples of other companies on the ICCA website will be helpful. Why donʼt you consider preparing GSS with other companies manufacturing the same substance? GPS promotes a stakeholder dialogue on science- and risk-based chemicals management The goal of GPS activities is not to prepare GSS only. The important point for implementing GPS is To implement risk assessment and To communicate risk management measures in an easily understandable way to all the interested stakeholders.
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