DURAN GROUP DISPENSER. Safe and precise dispensing system

DURAN GROUP DISPENSER Safe and precise dispensing system

Dispensing of liquid media made easy DURAN laboratory glassware ensures that work in the laboratory is carried out safely, precisely and smoothly. A system concept is of prime importance where the further development of products is concerned. This is true of the new, high-quality, DURAN Group dispensers, which now make the dispensing of liquids directly from DURAN laboratory glass bottles even easier and safer. They provide high accuracy, conform to DIN EN ISO 8655 and ensure optimum reproducibility. Precise dosing in the twinkling of an eye The DURAN Group dispenser can be screwed directly onto the bottle thread. The required volume is set on the dispenser and then dosed by depressing the precisely engineered plunger. The smoothly moving cylinder can be operated with one hand making serial dosing convenient. Thanks to their simple and precise volume adjustment, DURAN Group dispensers can be used in a wide variety of applications, with the metered quantity being quickly matched to the application in question.

Reliably leak-tight permanently resistant The thread of the DURAN Group dispenser is matched to the GL 45 thread of the DURAN laboratory glass bottle. This ensures optimum sealing and reduces any loss of media. Additionally, safe storage of the contents and protection against escaping vapour is ensured. The discharging tube can also be tightly closed with a cap. As the threads of the DURAN laboratory glass bottles and the DURAN Group dispensers are compatible with each other, we recommend their use as a complete system. By using the supplied adapters (GL 28, GL 32, GL 38, S 40) these dispensers can also be used for other thread sizes. Alongside borosilicate 3.3 glass, only high quality plastics such as PTFE, ETFE, PFA, FEP and a platinum-iridium alloy come into contact with the media. Hence the DURAN Group dispensers are resistant against most acids, bases and solvents, nearly wear-free and therefore have a very wide range of application. A PFA sealing lip adjacent to the cylinder wall prevents crystal formation when used with media which crystallise easily so that sticking of the piston is prevented.

Easy handling thanks to directly pushed piston complete with PFA sealing lip prevents sticking due to crystal formation Fast, easy and precise volume setting Very precise glass cylinder protected by a plastic cover Dispenser fitted on the bottle rotates freely through 360 GL 45 thread, precisely matched to DURAN laboratory glass bottles extremely leak-tight No dripping once discharge tube closure cap in place Only high quality materials used for the inner surfaces good chemical resistance universal use Adjustable telescopic tube can be matched to the bottle size

The dosing system with many advantages Original accessories for DURAN laboratory glass bottles, matched to GL 45 thread, therefore especially leak-tight and offers protection against vapour Optimum precision dispensing Reliable reproducibility Simple operation, even with one hand PFA sealing lip prevents crystal formation and consequently sticking of the piston Wide range of applications Modular design, easy to dismantle and clean A 121 C DIN ISO 8655 Made in Germany

DURAN Group dispenser + certificate + DURAN laboratory glass bottles: the complete one-stop solution Service is a priority for us. Thus all DURAN Group dispensers are supplied complete with a batch certificate, which includes the individual serial number so that traceability is ensured and conforms to the error limits to DIN EN ISO 8655. Certified quality: With a serial number for traceability Device type Confirms error limits adhere to DIN EN ISO 8655 Listing with names of the test equipment used Error limits as per DIN EN ISO 8655 Nominal volume: 2.5 ml 5.0 bis 100,0 ml Accuracy: ± 0.6 % ± 0.5 % Coefficient of variation: 0.1 % 0.1 % The accuracy (A) indicates how close the mean value is to the actual value and corresponds to the systematic error. The coefficient of variation (CV) indicates how close the individual measurements are to each other and corresponds to the random error.

Cat. no. Description Volume range DIN thread GL Adapters 29 115 03 DURAN Group Dispenser 0.25 2.5 ml 0.25 2.5 ml 32 GL 28, GL 45, S 40 29 115 06 DURAN Group Dispenser 0.5 5.0 ml 0.5 5.0 ml 32 GL 28, GL 45, S 40 29 115 09 DURAN Group Dispenser 1.0 10.0 ml 1.0 10.0 ml 32 GL 28, GL 45, S 40 29 115 14 DURAN Group Dispenser 2.5 25.0 ml 2.5 25.0 ml 45 GL 32, GL 38, S 40 29 115 17 DURAN Group Dispenser 5.0 50.0 ml 5.0 50.0 ml 45 GL 32, GL 38, S 40 29 115 24 DURAN Group Dispenser 10.0 100.0 ml 10.0 100.0 ml 45 GL 32, GL 38, S 40 Scope of delivery: DURAN Group dispenser, three PP threaded adapters (size see table), telescopic intake tube (200 350 mm), assembly key, instructions for use, quality certificate with specification of the test values. A summary of the spare parts can be found in the instructions for use supplied with the product. The perfect system the DURAN Group dispenser and the matching DURAN laboratory glass bottles The threads of the dispensers are matched to DURAN laboratory glass bottles. This ensures optimum sealing thus reducing any loss of media. Due to their excellent chemical resistance, the DURAN laboratory glass bottles are ideally suited to the preparation of solutions and the storage of even aggressive chemicals. The wide product range of the DURAN Group, as a world-wide leading manufacturer, offers a large number of variants and a comprehensive selection of original accessories. For more information, see www.duran-group.com.

DURAN Group GmbH Hattenbergstraße 10 D-55122 Mainz Tel. +49 (0)6131/66-4131 Fax +49 (0)6131/66-4016 info.duran@duran-group.com www.duran-group.com 6038113 e 03115.0 ba/jo Printed in Germany

DURAN GL 45 LABORATORY GLASS BOTTLES AND ACCESSORIES The perfect solution for every application

Table of contents DURAN LABORATORY GLASS BOTTLES: THOROUGHLY PROVEN UNIVERSALLY APPLICABLE 03 THE ORIGINAL: DURAN GL 45 LABORATORY GLASS BOTTLE 06 THE LIGHT PROTECTED: DURAN GL 45 LABORATORY GLASS BOTTLE IN AMBER 07 THE COATED: DURAN GL 45 PROTECT LABORATORY GLASS BOTTLE 08 THE SPACE SAVER: DURAN GL 45 SQUARE BOTTLE 09 THE TOP CLASS: DURAN GL 45 PREMIUM BOTTLE 10 THE PRESSURE TIGHT: DURAN GL 45 PRESSURE PLUS LABORATORY GLASS BOTTLE 13 THE COMPLETE: DURAN GL 45 HPLC-LABORATORY GLASS BOTTLE 14 FOR PERFECT INTERACTION: ACCESSORIES FOR DURAN LABORATORY GLASS BOTTLES 17 THE HIGHEST EXPECTATION FULFILLED: PREMIUM CAP 18 SIMULTANEOUSLY POROUS AND SEALING: MEMBRANE CAP 19 SECURITY AT A GLANCE: TAMPER-EVIDENT SCREW 20 INCREASED RESISTANCE: PBT CAP 21 DISTINGUISHABLE: COLOURED SCREW CAP 22 THE PROFESSIONAL CONNECTION: CONNECTION SYSTEMS FOR DURAN LABORATORY GLASS BOTTLES 24 DURAN PROPERTIES: BENCHMARK FOR THE HIGHEST QUALITY 16

DURAN LABORATORY GLASS BOTTLES: THOROUGHLY PROVEN UNIVERSALLY APPLICABLE 03 DURAN laboratory glass bottles impress because of their outstanding properties. In more than thirty years of production, the bottles have been consistently developed and improved. Thanks to this experience, the DURAN GROUP offers quality that remains unmatched. With numerous variants and the comprehensive original equipment from DURAN, a broad range of high-quality products and systems is available, permitting almost unlimited applications.

04 The advantages at a glance Standardised GL-thread and matching cap systems for particularly tight sealing and simple, clean pouring out Outstanding chemical resistance and near inert behaviour no interfering ion exchange High temperature and thermal shock resistance ideal for autoclaving and dry sterilising Sturdy design and uniform wall thickness distribution for improved safety and longer service life Transparent contents and volume can be quickly checked Glass Type 1 (neutral glass) conforming to USP/EP especially suited to applications in the pharmaceutical and food industries Very steady due to large base Easy labelling thanks to large labelling field Practicality easy to read, permanent graduations Retrace Code Using the eight-character retrace code and the corresponding article number, the batch and quality certificate for every DURAN laboratory glass bottle can be obtained at www.duran-group.com.

06 THE ORIGINAL: DURAN GL 45 LABORATORY GLASS BOTTLE This classical bottle is an essential in every laboratory and has shown itself to be a reliable partner for countless applications thanks to the proven properties of DURAN glass. The outstanding DURAN quality enables a wide spectrum of use from long-term storage through to the most demanding applications in the pharmaceutical industry. Proven DURAN properties Large labelling field Scale with graduation Complete with PP screw cap and pouring ring (also available without cap and pouring ring) Retrace code Autoclavable Sizes: 25 ml to 20,000 ml Capacity DIN-Thread d h Pack Order No. ml GL mm mm Quantity 21 801 145 25 25 36 74 10 21 801 175 50 32 46 91 10 21 801 245 100 45 56 105 10 21 801 365 250 45 70 143 10 21 801 445 500 45 86 181 10 21 801 545 1,000 45 101 230 10 21 801 635 2,000 45 136 265 10 21 801 735 5,000 45 182 335 1 21 801 865 10,000 45 227 415 1 21 801 885 15,000 45 268 450 1 21 801 915 20,000 45 288 510 1

THE LIGHT PROTECTED: DURAN GL 45 LABORATORY GLASS BOTTLE IN AMBER 07 The amber DURAN laboratory glass bottle also protects media from light radiation with a wavelength between 300 and 500 nm. It is, therefore, particularly suitable for use with lightsensitive media and for the long-term storage of substances. UV protection up to 500 nm wavelength Consistent external application of the colour; internal surfaces have standard DURAN glass properties Uniform amber colour as a result of innovative technology Special thermal method also results in long durability and good chemical resistance of the amber colour Retrace code Autoclavable Sizes: 25 ml to 20,000 ml Capacity DIN-Thread d h Pack Order No. ml GL mm mm Quantity 21 806 14 25 25 36 70 10 21 806 17 50 32 46 87 10 21 806 24 100 45 56 100 10 21 806 36 250 45 70 138 10 21 806 44 500 45 86 176 10 21 806 54 1,000 45 101 225 10 21 806 63 2,000 45 136 260 10 21 806 73 5,000 45 182 330 1 21 806 86 10,000 45 227 410 1 21 806 88 15,000 45 268 445 1 21 806 91 20,000 45 288 505 1

08 THE COATED: DURAN GL 45 PROTECT LABORATORY GLASS BOTTLE When handling particularly valuable or dangerous media, use of the DURAN Protect laboratory glass bottle is recommended. With its external plastic coating, it offers effective protection in daily laboratory work. If the outside is damaged, the coating holds the glass together, so that leakage of the medium is slowed or even stopped completely. Scratch, splinter and partial leak protection Highly transparent PU coating Ideal for storage and transport Suitable for microwaving Highly resistance, long service-life coating Retrace code Autoclavable Sizes: 25 ml to 5,000 ml Capacity DIN-Thread d h Pack Order No. ml GL mm mm Quantity 10 926 76 25 25 36 70 10 10 926 77 50 32 46 87 10 21 805 24 100 45 56 100 10 21 805 36 250 45 70 138 10 21 805 44 500 45 86 176 10 21 805 54 1,000 45 101 225 10 21 805 63 2,000 45 136 260 10 21 805 73 5,000 45 182 330 1

THE SPACE SAVER: DURAN GL 45 SQUARE BOTTLE The DURAN square bottle sits, thanks to its square shape, particularly well and securely in the hand. Moreover, it saves space and is more economical whether in autoclaves, in drying cabinets, in ovens, in storage or in washers. For example, seventy two 100 ml square bottles can be placed on a given surface rather than fifty 100 ml standard bottles and processed for the same costs. This corresponds to a space saving of 44 percent. Ergonomic handling Highly stable Good stackability Complete with PP screw cap and pouring ring Retrace code Autoclavable Sizes: 100 ml to 1,000 ml Capacity DIN-Thread d h Pack Order No. ml GL mm mm Quantity 21 820 245 100 32 50 109 10 21 820 365 250 45 64 143 10 21 820 445 500 45 78 181 10 21 820 545 1,000 45 94 222 10

10 THE TOP CLASS: DURAN GL 45 PREMIUM BOTTLE The DURAN Premium bottle is a consistent development of the standard bottle with GL 45 thread and blue screw cap. Alongside the proven material properties, the Premium bottle offers additional advantages that, first and foremost, contribute to safety in the laboratory while also simplifying handling. In addition, it supports a wider range of uses than standard laboratory glass bottles. Completed with an enhanced temperature-resistant screw cap manufactured from TpCh260 (similar to PFA) including a matching pouring ring (can be used from -196 C to +260 C); the raw material conforms to USP Class VI PTFE coated silicone seal Dye-free cap and pouring ring to prevent marking or contamination of ovens, drying chambers and sterilisation cabinets Scale accuracy to ± 5 % Additional scale for reading off the filling level as well as the quantity removed The entire system comprising bottle, cap and pouring ring conforms to USP/FDA. DMF is available upon request (DMF Nr. 19757) Ideal for sterilisation processes such as hot-air or dry sterilisation and depyrogenation Retrace code Batch certificate available Autoclavable Sizes: 100 ml to 1,000 ml Capacity DIN-Thread d h Pack Order No. ml GL mm mm Quantity 11 270 75 100 45 56 100 10 11 270 76 250 45 70 138 10 11 270 77 500 45 86 176 10 11 270 78 1,000 45 101 225 10

11 For optimum safety Guaranteed thermal shock resistance up to Δ 160 K, proven according to the stringent specifications of TÜV Rheinland and confirmed by the GS-indication (TÜV ID:0000020715)

12

The PRESSURE TIGHT: DURAN GL 45 PRESSURE PLUS LABORATORY GLASS BOTTLE: 13 Where applications involving pressures or vacuums are concerned, the DURAN pressure plus is first choice. Thanks to a modified geometry, the bottle has a guaranteed pressure-resistance and consequently offers optimum safety both for user and content. Special geometry based on ISO 4796 Vacuum or pressure resistance guaranteed from -1 bar to +1.5 bar Safety tested by the TÜV, in accordance with EN 1595 (TÜV ID:0000020716) Blue printing to visually distinguish it from the standard bottle Retrace code Autoclavable Sizes: 250 ml to 1,000 ml Capacity DIN-Thread d h Pack Order No. ml GL mm mm Quantity Clearly 10 922 34 250 45 70 138 10 10 922 35 500 45 86 176 10 21 810 54 1,000 45 101 225 10 Amber 10 943 67 250 45 70 138 10 10 943 68 500 45 86 176 10 21 816 54 1,000 45 101 225 10

14 THE COMPLETE: DURAN GL 45 HPLC LABORATORY GLASS BOTTLE The DURAN HPLC laboratory glass bottle represents a finished system: it comprises the pressure-resistant DURAN pressure plus laboratory glass bottle and a screw cap with four ports. This permits simultaneous feeding of three stations from one container. At the same time, a membrane filter can be optionally applied to the fourth outlet to permit sterile pressure equalization. It can be used with tube diameters of 1.6 mm (1/16 inch) and 3.2 mm (1/8 inch). Unused ports can be closed with a silicone seal. Capacity DIN-Thread d h Pack Order No. ml GL mm mm Quantity 11 298 21 500 45 86 176 * 2 11 298 20 1,000 45 101 225 * 2 * bottle only Spare parts Description Pieces 11 298 12 Screw cap HPLC GL 45 1 11 298 13 Spare set for HPLC screw cap 1 11 378 01 Pressure equalization set for 4-port cap 1 11 298 19 Spare membrane filter for pressure equalization set 0.2 µm 2

15 Variable system with lots of advantages All-in-one laboratory bottle including 4-port screw cap ready for immediate use (spare parts available separately) Based on the DURAN pressure plus for information see p.13; bottle can also be ordered separately Safe, inexpensive working in closed systems, toxic gases are largely retained in the bottle and the evaporation of expensive substances is reduced Universal system screw cap with standardised GL 45 thread PP cap can be autoclaved together with the bottle and thus reused many times over Optional silicone seals (available individually) can also be used as a septum, therefore retrospective addition of additives is possible Problem solver for numerous applications Feeding of HPLC automated machines with solvents (eluents) Disposal of waste media Titration systems Any closed system in which a sterile transfer of media is required and as a result of which pressure arises (only in conjunction with DURAN pressure plus bottle) Biotechnology processes, e.g. to pump additives (culture media etc.) from reservoir vessels into reaction vessels Automated, closed processes to transfer pure, sterile media Transfer of harmful to health, toxic substances in closed systems (to reduce out-gassing) Further information about the connection systems for DURAN laboratory glass bottles with two and three ports can be found on page 24.

16 DURAN PROPERTIES: BENCHMARK FOR THE HIGHEST QUALITY Proven through decades of practical use, DURAN products set benchmarks where resistance and safety are concerned. Particularly when compared with plastic, the individual material properties of DURAN offer clear advantages. Choose original DURAN laboratory glass bottles and accessories because top quality tolerates no compromises. Temperature resistance Serviceable up to a maximum of 500 C (not caps etc) High thermal shock resistance ( 100 K) Ideal for filling with hot media and carrying out sterilisation processes Autoclavable Suitable for use in microwaves Chemical resistance Hydrolytic resistance corresponding to class I as per DIN ISO 719, neutral glass/glass type 1 as per USP/EP Acid resistance corresponding to class 1 as per DIN 12116 Base resistance corresponding to class 2 as per ISO 695 Professional quality assurance Uniform wall thickness distribution Bubble and streak-free glass Precise dimensions and narrow tolerances Retrace code Retrace Code Using the eight digit retrace code and the corresponding article number, the batch and quality certificate for every DURAN laboratory glass bottle can be obtained at www.duran-group.com.

FOR PERFECT INTERACTION: ACCESSORIES FOR DURAN LABORATORY GLASS BOTTLES 17 The combination of DURAN laboratory glass bottles with original equipment guarantees, right down to the finest detail, matching systems that consequently deliver optimum results. Whether temperature resistance, chemical resistance, USP conformity or leak-tightness with its comprehensive range of caps and further accessories, DURAN has the right solution for every requirement. The table at the end of the brochure offers an overview.

18 THE HIGHEST EXPECTATION FULFILLED: ACCESSORIES FOR DURAN LABORATORY GLASS BOTTLES Thanks to its highly resistant material, the Premium cap is optimally suited to use for chemically and thermally demanding processes. Its high temperature resistance makes it the perfect partner to the DURAN Premium bottle. The DURAN laboratory glass bottle and Premium cap form a system that is precisely tailored to sterilisation processes such as hot-air or dry sterilisation as well as depyrogenation. Neither cap or pouring ring contain any dye to prevent marking or contamination of ovens, drying chambers and sterilisation cabinets by dye which could otherwise be dissolved out. The materials used correspond to the specifications of the FDA/USP/EP. Consequently, the Premium cap is particularly predestined to use in the pharmaceutical, chemical and food industries. Exceptionally temperature resistant from -196 C to +260 C Made from TpCh260 (similar to PFA); the raw material conforms to USP class VI No dye additives (leaching of dyes is excluded) High chemical resistance Extremely leak-tight through use of PTFE-coated silicone seal Ideal for dry-sterilisation/high temperature applications Particularly suited to storage and transport DMF available upon request (DMF no. 19757) Retrace code Autoclavable Item No. Thread Pack Quantity Cap 10 886 79 GL 45 5 Pouring ring 10 886 78 GL 45 5

SIMULTANEOUSLY POROUS AND SEALING: MEMBRANE CAP FOR DURAN LABORATORY GLASS BOTTLES 19 The membrane screw cap enables pressure equalization through a PTFE membrane, while the bottle remains tightly closed. This makes the cap ideal for autoclaving processes, because the contamination risk is dramatically lowered. Liquids, solids, and dirt particles cannot enter: the bottle contents remain sterile, even during storage. The membrane cap is also suitable for storing gas generating media. For all GL 45, GL 32 and GL 25 threads From proven PP material With welded-in PTFE membrane (0.2 μm) Membrane is only gas-permeable, not liquid-permeable 2-way membrane with pressure equalization for differential pressures greater than 0.1 bar Temperature resistant to +140 C Ideal for autoclaving processes or for storage of gas generating media Item No. Thread Pack Quantity 11 832 50 GL 25 5 11 832 51 GL 32 5 10 886 55 GL 45 5

20 SECURITY AT A GLANCE: TAMPER-EVIDENT CAP FOR DURAN LABORATORY GLASS BOTTLES The tamper-evident cap ensures the bottle content is securely stored, particularly when transporting valuable or critical media. When first closed, the plastic ring sits firmly over the bottle throat. If the cap is opened, the perforation tears and the plastic ring is retained around the throat. It is immediately and visibly apparent if the contents have retained their integrity. For all GL 45 threads Proven PP material Temperature resistant to +140 C Cap can also be used after the first untwisting or breaking of the perforations as a standard screw cap Available with lip (blue/red) or PTFE-coated silicone seals (blue/yellow) Autoclavable Item No. Thread Options Pack Quantity 10 175 26 GL 45 with lip seal 10 11 558 86 GL 45 with PTFE sealing disk 10

INCREASED RESISTANCE: PBT CAP FOR DURAN LABORATORY GLASS BOTTLES 21 Complementing the screw caps produced from PP and TpCh260 there is a further version manufactured from PBT. The cap is available with a PTFE coated silicone seal (increases the leak-tightness) or as a screw connection cap with aperture, e.g. for use with septa. For all GL 45 threads Temperature resistant to +180 C PTFE coated silicone seal More chemically resistant than PP Matching colour pouring ring Autoclavable Item No. Thread Colour Pack Quantity Caps 29 240 28 GL 45 Red 10 29 240 19 GL 32 Red 10 29 240 13 GL 25 Red 10 29 240 11 GL 18 Red 10 29 240 08 GL 14 Red 10 Pouring ring 29 244 28 GL 45 Red 10 29 244 19 GL 32 Red 10 Cap with aperature 29 227 10 GL 45 Red 10 29 227 08 GL 32 Red 10 29 227 09 GL 25 Red 10 29 227 06 GL 18 Red 10 29 227 05 GL 14 Red 10

22 DISTINGUISHABLE: COLOUR SCREW CAPS FOR DURAN LABORATORY GLASS BOTTLES The standard PP screw cap is available in blue, green, yellow and grey with matching pouring rings. In addition to clear labelling of laboratory glass bottles, the colour caps contribute to unambiguous marking. Different media can be distinguished at a glance and hence easily kept separate, even when the bottles are open. The clear marking helps prevent interchanging of caps and with it the carry over of substances. For all GL 45 threads From proven PP material Temperature resistant to +140 C In colours blue, green, yellow and grey Matching coloured pouring rings Autoclavable Item No. Threads Colour Pack Quantity Screw caps 29 338 286 GL 45 Green 10 29 338 280 GL 45 Yellow 10 29 239 28 GL 45 Blue 10 29 338 288 GL 45 Grey 10 29 239 19 GL 32 Blue 10 29 239 13 GL 25 Blue 10 Pouring rings 10 899 11 GL 45 Green 10 10 899 17 GL 45 Yellow 10 29 242 28 GL 45 Blue 10 10 899 14 GL 45 Grey 10 29 242 19 GL 32 Blue 10

24 THE PROFESSIONAL CONNECTION: CONNECTION-SYSTEM FOR DURAN LABORATORY GLASS BOTTLES The connection systems for DURAN laboratory glass bottles enable safe transfer of liquid media within a closed and sterile system. Therefore they are ideally suited to use in chemistry and biotechnology laboratories. Successfully used in numerous applications Feeding of HPLC automated machines with solvents (eluents) Disposal of waste media Titration systems All closed systems in which a sterile transfer of media is required and as a result of which pressure results (only in conjunction with DURAN pressure plus bottle) Biotechnology processes, e.g. to pump additives such as culture media etc. from reservoir vessels into reaction vessels Automated, closed processes to transfer pure, sterile media Transfer of harmful-to-health, toxic substances in closed systems (to reduce out gassing) Autoclavable

25 How it works: flexible working with system The basis of the connection system for DURAN laboratory bottles are screw caps with GL 45 threads and two or three outlets or ports. Liquid media can be added to or removed from bottles using the tube connections. Using a universal GL 14 tube adapter and different inserts, four different tube diameters can be used. An additional membrane filter with 0.2 μm pore size permits sterile pressure equalization via one of the outlets. This flexible, modular system provides the option of combining various components according to need and application. The components are compatible with each other and are used in conjunction with original DURAN GL 45 laboratory glass bottles. To increase safety in the laboratory, use of the pressure-resistant DURAN pressure plus laboratory glass bottle is to be recommended. Due to its modified geometry, a pressure-resistance of -1 bar to +1.5 bar is assured, as confirmed by TÜV. One system many advantages Wide range of uses, because the screw cap is based on the standard GL 45 thread Four different tube diameters can be used (1.6 mm [1/16 Inch]; 3.0 mm; 3.2 mm [1/8 Inch]; 6.0 mm [1/4 Inch]) The components for the 2- and 3-port system are identical and interchangeable Unused ports can be sealed with a blanking cap Due to their composition (PP and PTFE), the caps and all individual components are autoclavable and are thus easily reused; dismantling into individual parts is not necessary Through working in a closed system, toxic gases are largely retained in the bottle and the evaporation of expensive substances is reduced Flexible modular system for individual assembly according to application Temperature resistant to +140 C Autoclavable

26 Item No. 1129751 1129750 1137799 1129814 DURAN products can be obtained from your specialist laboratory dealer. Order addresses and other details about the items (e.g. technical information) can be found under www.duran-group.com or in the DURAN laboratory glassware catalogue. 1129815 1129816 1129817 1129818 1156292 Special safety caps and wide-neck bottles are contained in the brochures DG Safety Caps and DURAN GLS80 Glass bottles with wide neck.

Product Item No. Material Colour Temperature resistance Chemical resistance Tightness Conformity DIN- Threads Special properties Additional availabel sizes Caps Premium Cap 10 886 79 TpCh260/ PTFE/Silicone colourless -196 C/+260 C +++ +++ FDA/ USP GL 45 Sealing disk/ Batch Code on item - Membrane Cap 10 886 55 PP/PTFE Blue -40 C/+140 C + + FDA GL 45 Pressure equalizat. from 0.1 bar GL 32, 25 PP Cap Tamper-evident Cap PBT Cap 29 240 28 29 239 28 PP Blue -40 C/+140 C + + FDA GL 45 GL 32, 25 29 338 286 PP Green -40 C/+140 C + + FDA GL 45-29 338 280 PP Yellow -40 C/+140 C + + FDA GL 45-29 338 288 PP Grey -40 C/+140 C + + FDA GL 45-10 175 26 PP Blue/ Red -40 C/+140 C + + FDA GL 45 Tamperevident cap - 11 558 86 PP Blue/ Tamper-evident cap with Yellow -40 C/+140 C ++ ++ FDA GL 45 sealing disk - PBT/PTFE/ Silicone Red -45 C/+180 C ++ ++ FDA GL 45 PBT Aperture Cap 29 227 10 PBT Red -45 C/+180 C ++ ++ FDA GL 45 Pouring rings for Premium Cap 10 886 78 TpCh260 colourless -196 C/+260 C +++ +++ FDA/ USP With sealing disk Opening for e.g. septa GL 32, 25, GL 18, 14 GL 32, 25, GL 18, 14 GL 45 - PBT Cap 29 244 28 ETFE Red -45 C/+180 C ++ ++ GL 45 GL 32 29 242 28 PP Blue -40 C/+140 C + + FDA GL 45 GL 32 PP Cap 10 899 11 PP Green -40 C/+140 C + + FDA GL 45-10 899 14 PP Yellow -40 C/+140 C + + FDA GL 45-10 899 17 PP Grey -40 C/+140 C + + FDA GL 45 -

Product DURAN GL 45 Connection System Item No. Material Colour 2/3-Ports Temperature resistance Chemical resistance Tightness Conformity DIN- Threads Special properties Screw cap GL 45, 2-ports GL 14 11 297 50 PP Blue/Grey -40 C/+140 C + + FDA GL 45/14 2-Ports (GL 14) Screw cap GL 45, 3-ports GL 14 11 297 51 PP Blue/Grey -40 C/+140 C + + FDA GL 45/14 3-Ports (GL 14) Screw cab GL 14 for tube connection 11 298 14 PP Blue -40 C/+140 C + + - GL 14 Insert for screw cap GL 14, 1.6 mm [1/16 inch] iø Insert for screw cap GL 14, 3.0 mm [-1/8 inch] iø Insert for screw cap GL 14, 3.2 mm [1/8 inch] iø Insert for screw cap GL 14, 6.0 mm -1/4 inch] iø 11 298 15 11 298 16 11 298 17 11 298 18 Screw cap, GL 14 Red 11 562 92 Pressure equalization set for 2- and 3-port screw cap (incl. 0.2ųm membrane filter) Spare membrane filter for pressure equalization 0.2 μm 4-Ports 11 377 99 PTFE/ Silicone PTFE/ Silicone PTFE/ Silicone PTFE/ Silicone PBT/ PTFE/ Silicone PBT/PP/ PTFE White -50 C/+230 C +++ ++ FDA - White -50 C/+230 C +++ ++ FDA - White -50 C/+230 C +++ ++ FDA - White -50 C/+230 C +++ ++ FDA - Red -45 C/+180 C ++ ++ FDA GL 14 White -40 C/+140 C + + GL 14 11 298 19 PP/PTFE White -40 C/+140 C + + - Screw cap HPLC GL 45 11 298 12 PP Blue/Grey -40 C/+140 C + + GL 45 Spare set for HPLC cap 11 298 13 PP Blue/Grey -40 C/+140 C + + Pressure equalization set for 4 ports 11 378 01 PP Blue/Grey -40 C/+140 C + + Spare membrane filter for pressure equalization 0.2 µm 11 298 19 PP Blue/Grey -40 C/+140 C + + 4-Ports (complete set) 4-Ports (complete set)

29 ORDERING MADE EASY: c You would like to equip two bottles with a three port connection system. You would like to work with two different tube diameters (1.6 mm and 3 mm) and pressure equalization. Consequently, you need the following individual components (1, 2 and 3 shown in the illustration): screw cap GL 45 3 port (Art. No. 1129751) 1 pack (2 per pack) Insert for screw cap GL14 1.6 mm iø, (Art. No. 1129815) 2 packs (1 per pack) screw cap GL 14 (Art. No. 1129814) 2 packs (2 per pack) Insert for screw cap GL14 3.0 mm iø, (Art. No. 1129816) 2 packs (1 per pack) Pressure equalization set (complete) (Art. No. 1137799) 2 packs (1 per pack) d h Pack. Order No. Description Thread mm mm Qty 11 297 50 Screw cap GL 45, 2-port GL 14 GL 45 54 45 2 11 297 51 Screw cap GL 45, 3-port GL 14 GL 45 54 45 2 11 298 14 Screw cap GL 14 for tube connection GL 14 20 28 2 11 298 15 Insert for screw cap GL 14, 1.6 mm [1/16 inch] iø 13 13 1 11 298 16 Insert for screw cap GL 14, 3.0 mm [-1/8 inch] iø 13 13 1 11 298 17 Insert for screw cap GL 14, 3.2 mm [1/8 inch] iø 13 13 1 11 298 18 Insert for screw cap GL 14, 6.0 mm [-1/4 inch] iø 13 13 1 11 562 92 Screw cap GL 14, red GL 14 20 17 2 11 377 99 Pressure equalization set for 2- and 3-port screw cap (incl. 0.2 μm membrane filter) GL 14 20 63 1 11 298 19 Spare membrane filter for pressure equalization 0.2 μm 2 It s even easier with the DURAN HPLC laboratory glass bottle, the preassembled complete system

Titel DURAN Group GmbH Hattenbergstraße 10 55122 Mainz, Germany Tel. +49 (0)6131/66-4131 Fax +49 (0)6131/66-4038 info.duran@duran-group.com www.duran-group.com 6040390 e 090815.0 ba/re Printed in Germany

DURAN GLS 80 GLASS BOTTLES WITH WIDE NECK Large, wide neck ideal for filling and pouring.

GREATER CONVENIENCE FOR EVERYDAY LAB WORK We have extended our DURAN laboratory glassware range. Our new wide neck glass bottles with large, 80 mm diameter neck size are available in six different sizes. All sizes are also available in amber for light-sensitive media. This range also features a selection of quick- release caps.

ENDLESS APPLICATIONS SAFE AND EASY TO USE DURAN GLS 80 wide neck glass bottles are extremely versatile: ideal for pouring, filling, mixing, preparing, storing, transporting, dispatching, taking samples in the field and hot filling, whether in the laboratory or in production. The DURAN GLS 80 laboratory glassware range features a specially developed screw thread. The matching quick-release cap allows the bottle to be easily opened and closed with a minimum of turns. The 80 mm wide neck facilitates easy and safe charging and removal of powders, pastes, granules and liquids. Spoons, spatulas and tweezers can be manipulated with ease. Even large-volume funnels can be inserted into the bottles without any difficulty. The wide neck also makes cleaning the bottles particularly easy.

SPECIAL FEATURES OF THE DURAN GLS 80 WIDE NECK GLASS BOTTLE Wide neck screw thread 80 mm diameter, special thread design for rapid opening and closing. Inert and chemically resistant exceptional properties of DURAN eliminate problems with ion leaching. Traceability the eight-digit batch code allows the bottles to be traced back to the point of production, including the matching batch. The end-user can use the corresponding item number to retrieve a batch and quality certificate for any DURAN laboratory bottle at any time via the Internet. Mechanical strength the sturdy design of these wide neck bottles enhances safety and service life. Sterilisable excellent thermal properties for autoclaving and dry sterilization. Transparency contents and volume can be visually checked with ease. EU Design No. 381983 Stability the large, stable base area allows for safe and easy storage. Labelling provided with a printed white panel for labelling the contents. Graduated convenient, easy-to-read graduations indicating volume.

SPECIAL ADVANTAGES OF THE GLS 80 QUICK-RELEASE CAP User-friendly the special thread design enables the bottle to be opened and closed quickly with less than two turns of the cap. Temperature-resistant the polypropylene cap is autoclavable up to 140 C. Matching pouring ring for drip-free pouring

The DURAN GLS 80 wide neck glass bottle is available in three versions simply choose the most suitable bottle for your requirements. THE VERSATILE DURAN GLS 80 BOTTLE The wide opening for safe and easy handling of powders and liquids makes the DURAN GLS 80 bottle a versatile partner for all routine laboratory applications. Choose from six different bottle sizes, complete with quick-release plastic cap and pouring ring. Capacity diameter height* Description ml mm mm Pack unit Item no. GLS 80 laboratory bottle 500 101 148 10 1112627 GLS 80 laboratory bottle 1,000 101 218 10 1112713 GLS 80 laboratory bottle 2,000 136 248 10 1112715 GLS 80 laboratory bottle 5,000 182 311 1 1113949 GLS 80 laboratory bottle 10,000 227 395 1 1113950 GLS 80 laboratory bottle 20,000 288 483 1 1113951 GLS 80 pouring ring, blue, PP 77 7 10 1160166 * without cap

THE LIGHT-PROOF AMBER DURAN GLS 80 BOTTLE The amber DURAN laboratory bottle protects media from light in the 300 nm 500 nm wavelength range. This makes it particularly useful for working with light-sensitive media and for the long-term storage of substances. UV protection up to approx. 500 nm light wavelength only the outer surface of the glass is tinted, ensuring that the DURAN properties on the inside remain unchanged special heat treatment ensures that the amber tint is durable and chemically resistant available in sizes ranging from 500 ml to 20,000 ml Capacity diameter height* Description ml mm mm Pack unit Item no. GLS 80 laboratory bottle, amber 500 101 148 10 1160146 GLS 80 laboratory bottle, amber 1,000 101 218 10 1160147 GLS 80 laboratory bottle, amber 2,000 136 248 10 1160148 GLS 80 laboratory bottle, amber 5,000 182 311 1 1160149 GLS 80 laboratory bottle, amber 10,000 227 395 1 1160150 GLS 80 laboratory bottle, amber 20,000 288 483 1 1160151

THE PLASTIC-COATED DURAN GLS 80 PROTECT Ideal for handling particularly valuable or dangerous materials. The plastic coating (PU) on DURAN GLS 80 Protect provides effective protection during routine laboratory work and retains the contents if the glass becomes damaged. scratch-, leak- and shatter-resistant high transparency temperature range 30 C to + 140 C autoclavable suitable for use in microwaves stable and durable Capacity diameter height* Description ml mm mm Pack unit Item no. GLS 80 Protect laboratory bottle 500 101 148 10 1160152 GLS 80 Protect laboratory bottle 1,000 101 218 10 1160163 GLS 80 Protect laboratory bottle 2,000 136 248 10 1160164 GLS 80 Protect laboratory bottle 5,000 182 311 1 1160165 * without cap

DURAN FOR GREATER SAFETY Chemical resistance hydrolytic-resistant to DIN ISO 719, Class 1 neutral glass/ Type I glass in compliance with USP/EP acid-resistant to DIN 12 116, Class 1 alkali-resistant to DIN ISO 695, Class 2 Quality control Our professional quality control features uniform wall thickness distribution bubble- and streak-free glass precise dimensions and narrow tolerances Temperature resistance up to max. 500 C high thermal shock resistance ( 100 K) ideal for hot filling and carrying out sterilisation procedures (autoclaving) suitable for use in microwaves There are several good reasons for choosing DURAN GLS 80 wide neck glass bottles. Compared with plastic bottles, DURAN glass bottles with their proven material properties offer a wealth of benefits. DURAN GLS 80 wide neck bottles: see for yourself!

Attach tubes simply and conveniently using the flexible modular system ideal for transferring liquids. THE FLEXIBLE MULTI-PORT SYSTEM FOR DURAN GLS 80 WIDE NECK GLASS BOTTLES The multi-port system consists of a GLS 80 screw cap with four ports. The tubes are fed through these ports and secured with inserts and screw connections. There is a choice of 5 inserts, each with different internal diameter depending on the application. Unused ports can be fitted with a blanking cap, if necessary. Sterile pressure compensation can be achieved using the membrane filter set (0.2 µm pore size). standard GLS 80 screw thread five different tube diameters versatile components blanking caps for unused ports made from proven PP and PTFE autoclavable (temperature-resistant up to approx. 140 C) flexible, modular system The inserts and GL18 screw connections hold the tubes securely in place, eliminating problems caused by slippage, e. g. in HPLC plants. The sealed cap system reduces evaporation of media and keeps out impurities.

Item no. 1160176 1160167 1170682 1160174 1160173 1160172 1160171 1160170 1160169

SAMPLE ORDER: You want to fit two DURAN GLS 80 bottles with a 4-port system. You want to work with two different tube diameters (3.2 mm and 10 mm) and pressure equalisation. The redundant fourth port is fitted with a screw cap. You will need the following individual components (1, 2, 3 are shown in the illustration): GLS 80 screw cap with 4 ports (item no. 1160176)1x [pack unit 2 pieces] GL 18 screw cap for tube connection, blue (item no.1160174) 2x [pack unit 2 pieces] GL 18 insert for screw cap, 3.2 mm iø, (item no.1160169) 2x [pack unit 1 piece] GL 18 insert for screw cap, 10.0 mm iø, (item no.1160172) 2x [pack unit 1 piece] Pressure compensation set (complete), (item no.1160167) 2x [pack unit 1 piece] GL 18 screw cap, red (item no. 1170682) 1x [pack unit 2 pieces] diameter height* Description Thread mm mm Pack unit Item no. GL 18 screw cap with 4 ports GLS 80 86 ~ 60 2 1160176 Insert for screw cap, iø 3.2 mm GL 18 1 1160169 Insert for screw cap, iø 6.0 mm GL 18 1 1160170 Insert for screw cap, iø 8.0 mm GL 18 1 1160171 Insert for screw cap, iø 10.0 mm GL 18 1 1160172 Insert for screw cap, iø 12.0 mm GL 18 1 1160173 Screw cap for tube connection, blue GL 18 2 1160174 Pressure compensation set for 4-port GL 18 1 1160167 Screw cap, red GL 18 2 1170682

The membrane cap is both gas-permeable and liquid-tight. THE PERMEABLE MEMBRANE CAP FOR DURAN GLS 80 WIDE NECK GLASS BOTTLES The membrane screw-cap features a sterile membrane for pressure compensation. The cap is ideal for autoclaving and for storing or transporting gas-forming substances. Since pressure compensation takes place through the membrane, the membrane cap can be screwed on tightly during autoclaving, significantly reducing the risk of contamination. Since the membrane prevents the entry of liquids and solids, the contents of the bottle remain sterile. for all GLS 80 screw threads made from proven PP material with welded-on PTFE membrane (0.2 μm) temperature-resistant to +140 C 2-way membrane with pressure equalisation from 0.1 bar ideal for autoclaving ideal for storing gas-forming media diameter height Description Thread mm mm Pack unit Item no. Membrane cap, blue, PP GLS 80 86 40 2 1160168

All DURAN GLS 80 wide neck bottles, membrane caps and multi-port systems can be ordered directly from your laboratory supplier using the item numbers below. AT A GLANCE: PRODUCT OVERVIEW Bottles Capacity diameter height* Description ml mm mm Pack unit Item no. GLS 80 Laboratory bottle 500 101 148 10 1112627 GLS 80 Laboratory bottle 1,000 101 218 10 1112713 GLS 80 Laboratory bottle 2,000 136 248 10 1112715 GLS 80 Laboratory bottle 5,000 182 311 1 1113949 GLS 80 Laboratory bottle 10,000 227 395 1 1113950 GLS 80 Laboratory bottle 20,000 288 483 1 1113951 GLS 80 Laboratory bottle, amber 500 101 148 10 1160146 GLS 80 Laboratory bottle, amber 1,000 101 218 10 1160147 GLS 80 Laboratory bottle, amber 2,000 136 248 10 1160148 GLS 80 Laboratory bottle, amber 5,000 182 311 1 1160149 GLS 80 Laboratory bottle, amber 10,000 227 395 1 1160150 GLS 80 Laboratory bottle, amber 20,000 288 483 1 1160151 GLS 80 Protect laboratory bottle 500 101 148 10 1160152 GLS 80 Protect laboratory bottle 1,000 101 218 10 1160163 GLS 80 Protect laboratory bottle 2,000 136 248 10 1160164 GLS 80 Protect laboratory bottle 5,000 182 311 1 1160165 * without cap

Caps and accessories diameter height Description Thread mm mm Pack unit Item no. Quick-release cap, PP GLS 80 86 40 10 1112716 Pouring, blue, PP GLS 80 77 7 10 1160166 Membrane cap, PP GLS 80 86 40 2 1160168 GL 18 screw cap with 4 ports GLS 80 86 ~ 60 2 1160176 Insert for screw cap, iø 3.2 mm GL 18 1 1160169 Insert for screw cap, iø 6.0 mm GL 18 1 1160170 Insert for screw cap, iø 8.0 mm GL 18 1 1160171 Insert for screw cap, iø 10.0 mm GL 18 1 1160172 Insert for screw cap, iø 12.0 mm GL 18 1 1160173 Screw cap for tube connection, blue GL 18 2 1160174 Pressure equalisation set for 4-port GL 18 1 1160167 Screw cap, red GL 18 2 1170682

DURAN Group GmbH Hattenbergstraße 10 55122 Mainz, Germany Phone +49 (0)6131/66-4131 Fax +49 (0)6131/66-4016 info.duran@duran-group.com www.duran-group.com 50098 e 090713.0 ba/dh Printed in Germany