HD-S B-3 B-2. No Fig. 2. Recommended vessel diameter (mm) B-1 B-2 B-3 HD-S

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Micro Clamps HD-S B-3 B-1 B-2 No. 00396-01 No. 00398-02 No. 00400-03 No. 00325-00 Clamp Size and Clamp Pressure When choosing the right size clamp for your work, clamp pressure is an important consideration. Clamp pressure is determined by the closing force of the clamp (in grams), divided by the area of the vessel wall that is compressed between the jaws (in square millimeters). Thus, the smaller the vessel, the higher the pressure exerted. Each size of clamp has its own different and carefully calibrated closing force. Each clamp size is designed for a specific range of vessel diameters (Fig. 1). Despite the wide range of closing forces, the pressure exerted by each clamp, big or small, remains consistent throughout the series. Each size of clamp exerts a pressure of 5gm/mm 2 when used on the largest vessel in its range, and 15gm/mm 2 when used on the smallest vessel. Even at the higher range, S&T s micro clamps have the gentlest working pressure of any small vessel clamp available. The table (Fig. 2) summarizes the relationship between clamp size, recommended vessel diameter and clamp pressure. Vessel diameter refers to the external diameter of the vessel in its natural state of full dilation. There is a 50% overlap in the recommended vessel diameter range, between each clamp size and the next larger or smaller size. Thus, for every vessel diameter, with the exception of those at the extreme ends of the range, there will always be two suitable clamps. Whenever a choice arises, the smaller clamp should be selected to ensure a gentler, less pressured handling of the vessel. Applying Forceps for S&T Clamps 5 4 3 2 1 Recommended vessel diameter (mm) Fig. 2 clamp pressure (g/mm 2 ) 5 10 15 without lock, for clamp sizes B-1, B-2 and B-3 No. 00072-14 with lock, for clamp sizes B-1, B-2 and B-3 No. 00071-14 00071-14 shown B-1 B-2 B-3 HD-S 80 USA 1-800-521-2109 CANADA 1-800-665-5355 GERMANY +49 (0) 62 21 90 50 50 FINESCIENCE.COM

VASCULAR INSTRUMENTS For use with our 18055 series micro serrefine. For use with our 18055 series micro serrefine. Micro Serrefine With delicate, atraumatic serrations and 2 mm spring width. Used to obtain a clear surgical field for extended arterial cross-clamping. Caution: These clips should never be compressed with fingers; use only the appropriate applicator No. 18056-14 or No. 18057-14. This applicator features special U-shaped side supports for improved seating of the clips. It fits all six sizes of the micro clips shown to the right. No. 18055-01 -02-03 -04 Jaw Length (mm) 10 8 6 4 Jaw Width (mm) 2 2 1 0.75 Total Length (mm) 19 16 15 13 Jaw Pressure (gr) 60 85 100 125 No. 18055-05 -06 Micro clip applicator, with lock, No. 18056-14 Forceps type clip applicator, No. 18057-14 Jaw Length (mm) 6 4 Jaw Width (mm) 1 0.75 Total Length (mm) 17 16 Jaw Pressure (gr) 100 125 PRICES SHOWN IN THIS CATALOG ARE IN US CURRENCY SEE INSIDE FRONT COVER FOR ORDERING INFORMATION 81

Schwartz Micro Serrefine Strongly tensioned, non-serrated. 26 mm No. 18052-01 Dietrich Bulldog Clamps Serrated, good access to deep seated vessels. Closing pressure 50g. Weight 3g. Moria Vessel Clamps Finely serrated (atraumatic), gentle pressure, for vessels up to 2 mm in diameter, calibrated to 15g/mm 2. 1.8 mm wide, 3 cm long. Light Bend, 26 mm No. 18052-02 Sharp Bend, 26 mm No. 18052-03 52.5 mm No. 18038-45 Angled, 50 mm No. 18039-45 MORIA 201/A, 33 mm No. 18320-11 Mini Serrefine Smallest bulldog type hemostatic clamps, medium pressure, gentle serrations on inside of jaws, 2 mm wide. No. 18054-28 Curved, No. 18053-28 Bulldog Type Serrefine Serrated. No. 18050-28 Curved, No. 18051-28 Moria Bulldog Type Clamps Exquisitely made, no serrations on inside. 2 mm wide tips. MORIA MC43, 53 mm No. 18374-43 35 mm No. 18050-35 50 mm No. 18050-50 This bulldog artery spring clamp is fashioned from surgical titanium, and can be used with a minimum of distortion for MRI investigations. Curved, MORIA MC44, 53 mm No. 18374-44 30 mm No. 18144-30 Curved, 35 mm No. 18051-35 50 mm No. 18051-50 82 USA 1-800-521-2109 CANADA 1-800-665-5355 GERMANY +49 (0) 62 21 90 50 50 FINESCIENCE.COM

VASCULAR INSTRUMENTS Vascular Occluders used for constriction of blood vessels and soft organs Applications Fast, dependable zero-flow baseline determination in blood flow studies Partial to full occlusion of vessels for circulation research studies Prolonged implantations, such as chronic blood flow studies Constriction of soft organs in acute or chronic applications Vascular Occluder - VO-1.5 N Lumen Diameter 1.5 mm, Cuff Width <3.5 mm, Cuff Thickness 1.5 mm No. 18080-01 Vascular Occluder - VO-2 Lumen Diameter 2 mm, Cuff Width 5 mm, Cuff Thickness 1.5 mm No. 18080-02 Operation Step 1 Apply the Occluder cuff around the exposed blood vessel. Secure it in place with suture material through the eyelets. Step 2 Occlude the vessel to any degree desired by inflating the diaphragm with air or liquid injected into the actuating tube using a syringe and blunt needle. Clamp the tubing to maintain occlusion of the vessel over time. Step 3 To deflate, simply withdraw the air or liquid. Vascular Occluder - VO-3 Lumen Diameter 3 mm, Cuff Width 5 mm, Cuff Thickness 1.5 mm No. 18080-03 The actuating tube length is 90 cm and measures 0.76 mm ID x 1.6 mm OD Benefits of FST Vascular Occluders compared to similar devices: Occlusion is accomplished without traction on vessels or surrounding tissues The actuating tube may be exteriorized from the occlusion site for remote actuation Performance during implantations is reliable and consistent Autoclavable or cold sterilized, and easily maintained Made from soft, flexible 100% silicone rubber Fully operational with instant response using air, liquids, or inert gasses A - Lumen Diameter B - Cuff Width C - Cuff Thickness B C A Selection of the proper Occluder: The lumen diameter when deflated is usually the determining factor in the selection of the proper device. Select the occluder size that provides a slightly loose fit around the subject vessel. The cuff width and thickness will vary, depending on models and sizes. Silver Neuro Clips These one time use silver neuro clips are meant for permanent vessel occlusion. Pkg. of 100 No. 18040-00 PRICES SHOWN IN THIS CATALOG ARE IN US CURRENCY SEE INSIDE FRONT COVER FOR ORDERING INFORMATION 83

Ligation Aids For Blood Vessels and Nerves A handy instrument for leading a fine suture under and around a blood vessel for tying-off purposes. Also useful for ligating peripheral nerves. Grooves toward hole help threading. Vessel Dilators Highly modified forceps with elongated, parallel tips which are highly polished. Designed for controlled intraluminal vessel dilation. CANNULATION Right-handed, hole diam. 1 mm No. 18062-13 Left-handed, hole diam. 1 mm No. 18063-13 Ultra fine ligation aid, hole diam. 0.4 mm 10.5 cm, No. 18062-12 Highly polished, tip diameter 0.5 mm, angled off center, No. 18153-11 Flat handle 9 mm wide. Angled at 10, tip diameter 0.2 mm, No. 00125-11 Tips angled at 45, tip diameter 0.2 mm, No. 00276-13 84 USA 1-800-521-2109 CANADA 1-800-665-5355 GERMANY +49 (0) 62 21 90 50 50 FINESCIENCE.COM

VASCULAR INSTRUMENTS Micro Cannulation System for Small Blood Vessels This micro cannula is most helpful for quick and easy insertion in arteries and veins. It can be used as an indwelling catheter during long term experiments. With care, thorough rinsing and sterilization, it can be re-used several times. Total length (without stylus) is 8 cm. Detailed instructions are included. Not for clinical use. Features: Biocompatible Teflon tubing. 1 approach Cannula size 0.33mm O.D. - 0.16 mm I.D. A pointed stainless steel stylus (trocar), to aid in vascular penetration and allowing a maximum range of cannula manipulation during insertion. Contoured tip for ease of insertion, fitted with shoulder for tie-in to prevent accidental removal. Female luer connection for linkage to infusion lines. Cannulation system, 8 cm No. 18000-10 2 insertion CANNULATION 3 tie-in 18070-40 shown Micro Cannula 12 bevel tip Hard to obtain stainless steel micro cannula in gauges 30, 31, 33 and three lengths: 15, 40 and 90 mm. With medium, 12 bevel. With Luer lock hub. Pkg. of 6 Item Gauge OD mm ID mm Length No. 18070-15 30.3048.1524 15 mm No. 18070-40 30.3048.1524 40 mm No. 18070-90 30.3048.1524 90 mm No. 18071-15 31.2540.1270 15 mm No. 18071-40 31.2540.1270 40 mm No. 18071-90 31.2540.1270 90 mm No. 18073-15 33.2032.1016 15 mm No. 18073-40 33.2032.1016 40 mm No. 18073-90 33.2032.1016 90 mm Vessel Cannulation Forceps This vessel cannulation forceps is useful whenever a fine plastic tube has to be introduced into a small blood vessel of almost equal size. The hollowed jaws hold the tubing securely without deforming it. The tip of the tubing is directed exactly into the vessel opening without damage to the vessel from unwanted movement. For tubing between 0.5 and 1 mm OD, No. 00574-11 For tubing between 0.5 and 1 mm OD, No. 00571-13 For tubing of 0.35 mm OD, No. 00608-11 No. 00574-11 shown PRICES SHOWN IN THIS CATALOG ARE IN US CURRENCY SEE INSIDE FRONT COVER FOR ORDERING INFORMATION 85