ALLOGENEIC IMMUNOTHERAPY: WHERE DO WE STAND IN 2018?

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4TH INTERNATIONAL SYMPOSIUM IN?

INVITED SPEAKERS Huisheng Ai, Beijing, China Borje Andersson, Houston, USA Andrea Bacigalupo, Roma, Italy Ali Bazarbachi, Beirut, Lebanon Didier Blaise, Marseille, France Jaap Boelens, Utrecht, The Netherlands Attilio Bondanza, Milan, Italy Luca Castagna, Milan, Italy Christian Chabannon, Marseille, France Richard Childs, Bethesda, USA* Stefan Ciurea, Houston, USA Raynier Devillier, Marseille, France Ephraim Fuchs, Baltimore, USA Ivana Gojo, Baltimore, USA Suradej Hongeng, Bangkok, Thailand Jiong Hu, Shangai, China He Huang, Hangzhou, China Xiao Jun Huang, Beijing, China Jong Wook Lee, Seoul, South Korea Leo Luznik, Baltimore, USA Florent Malard, Paris, France Domenico Mavilio, Milan, Italy Mohamad Mohty, Paris, France Arnon Nagler, Tel Hashomer, Israel Daniel Olive, Marseille, France Simrit Parmar, Houston, USA Finn Petersen, Boise, USA Bipin Savani, Nashville, USA Luca Vago, Milan, Italy Norbert Vey, Marseille, France Ibrahim Yakoub-Agha, Lille, France * To be confirmed. IN? FRIDAY, 20 TH, 13.00 OPENING SESSION 13.30 SESSION 1 IMMUNOLOGY 13.30 Monoclonal antibodies: what s next? Daniel Olive, Marseille, France 14.00 Update on the role of B cells in allo-hct. Florent Malard, Paris, France 14.30 Immune reconstitution after Haplo HSCT. Domenico Mavilio, Milan, Italy 15.00 Discussion 15.15 SESSION 2 CELULAR IMMUNOTHERAPY 15.15 Genetic manipulation of NK cells for cancer immunotherapy. Richard Childs, Bethesda, USA* 15.45 Treg Adoptive immunotherapy. Simrit Parmar, Houston, USA 16.15 Discussion 16.30 Coffee break & exhibition visit 17.00 SESSION 3 CAR-T CELLS AND OTHERS? 17.00 Car-T cells: where are we in? Attilio Bondanza, Milan, Italy 17.30 Evolution of regulation for engineered cellular therapies. Christian Chabannon, Marseille, France 18.00 Car-T cells post allo HSCT. He Huang, Hangzhou, China 18.30 Novel allogeneic cell therapies of cancer. Ephraim Fuchs, Baltimore, USA 19.00 Discussion * To be confirmed.

SATURDAY, 21 TH, IN? 08.30 SESSION 4 AML AND MDS 08.30 The place of Haplo HSCT for AL in Europe: what are the trends? Arnon Nagler, Tel Hashomer, Israel 09.00 Familial or HLA matched HSCT for AML? Xiao Jun Huang, Beijing, China 09.30 Secondary Leukemia and haplo -SCT. Bipin Savani, Nashville, USA 10.00 Haplo for MDS. Ibrahim Yakoub-Agha, Lille, France 10.30 Discussion 10.45 Coffee break & exhibition visit 11.15 SESSION 5 RELAPSED/REFRACTORY AML 11.15 Loss of mismatched HLA in leukemia after stem-cell transplantation. Luca Vago, Milan, Italy 11.45 Is treating refractory leukemia with allo HSCT appealing? The leukemia doctor perspective. Norbert Vey, Marseille, France 12.15 How to choose a haplo donor: impact of disease status? Stefan Ciurea, Houston, USA 12.45 Lunch 14.00 SESSION 6 LYMPHOMAS 14.00 Familial or HLA matched HSCT for lymphoma? Luca Castagna, Milan, Italy 14.30 Prophylaxis of NHL relapse after transplant: what are the tools? Ali Bazarbachi, Beirut, Lebanon 15.00 Discussion 15.15 SESSION 7 NEW STRATEGIES TO IMPROVE RESULTS OF TRANSPLANTS 15.15 Post transplant Cy for HLA matchedand mismatched transplant: anything new? Leo Luznik, Baltimore, USA 15.45 Pre-transplant pharamacologic approach in non malignant and malignant diseases. Borje Andersson, Houston, USA 16.15 Towards predictable immune reconstitution after HCT for optimal survival chances. Jaap Boelens, Utrecht, The Netherlands 16.45 Discussion 17.00 Coffee break & exhibition visit 17.30 SESSION 8 TOXICITIES IN TRANSPLANT AND IMMUNOTHERAPIES 17.30 Haplo-ID transplant related complications: what we know, and what we need to learn. Finn Petersen, Boise, USA 18.00 Toxicities of Car-T cells. Mohamad Mohty, Paris, France 18.30 How to deal with older age in allo HSCT. Didier Blaise, Marseille, France 19.00 Discussion 20.30 Gala Dinner

SUNDAY, 22 TH, IN? 08.30 SESSION 9 NON MALIGANT DISEASES 08.30 Haplo HSCT for SAA: where are we in? Andrea Bacigalupo, Roma, Italy 09.00 Haplo HSCT for hemoglobinopathies. Suradej Hongeng, Bangkok, Thailand 09.30 Discussion 09.45 SESSION 10 EXPERIENCE FROM ASIA 09.45 RIC and ATG based haplo HSCT. Jong Wook Lee, Seoul, South Korea 10.15 Micro transplant for acute leukemia: a dream? Huisheng Ai, Beijing, China 10.45 Microtransplant from cord blood source. Jiong Hu, Shangai, China 11.15 Discussion 11.45 Coffee break & exhibition visit 12.15 SESSION 11 POST ALLO TREATMENTS 12.15 Treatment of AML relapse after transplant: what are the tools? Ivana Gojo, Baltimore, USA 12.45 Personalized allogeneic immunotherapy for AML. Raynier Devillier, Marseille, France 13.15 Discussion 13.15 CONCLUDING REMARKS 13.30 Farewell cocktail GENERAL INFORMATION CONGRESS VENUE Palais du Pharo 58, Bd Charles Livon - 13007 Marseille Tel.: +33 (0)4 95 09 59 00 - www.marseille-provence.com ACCOMMODATION Hôtel Novotel Marseille Vieux Port 36, Bd Charles Livon - 13007 Marseille Tel.: +33 (0)4 96 11 42 11 - www.novotel.com New Hotel of Marseille 71, Bd Charles Livon - 13007 Marseille Tel.: +33 (0)4 91 31 53 15 - www.new-hotel.com Radisson Blu Hôtel 38-40, quai de Rive Neuve, 13007 Marseille Tel.: +33 (0)4 88 44 52 00 - www.radissonblu.fr/hotel-marseille Ibis Budget Vieux Port 46, rue Sainte - 13001 Marseille Tel.: +33 (0)8 92 68 05 82 - www.ibis.com ORGANIZATION & REGISTRATION Com&Co - Etienne Jarry 15, Bd Grawitz - 13016 Marseille, France Tel.: +33 (0)4 91 09 70 53 Fax: +33 (0)4 96 15 33 08 Email: ejarry@comnco.com

IN? REGISTRATION FORM Return to Com&Co by: Post 15, Bd Grawitz - 13016 Marseille, France Email ejarry@comnco.com Fax +33 (0)4 96 15 33 08 O Pr O Dr O Mr O Ms Last name... First name... Institution/Company... Departement... Address... Post code...city... Country... Phone... Email... FREE PARTICIPATION ON: O Friday, April 20 th O Saturday, April 21 th O Sunday, April 22 th O Gala dinner