(ANZOD Registry) [Data collected to 31 st December 2004] Edited by. Mrs Leonie Excell Ms Penny Wride Professor Graeme R Russ

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(ANZOD Registry) 2005 Repor port [Data collected to 31 st December 2004] Edited by Mrs Leonie Excell Ms Penny Wride Professor Graeme R Russ Special Section on Heart and Lung Transplantation Contributed by Associate Professor Anne Keogh and Mr Ross Pettersson

FUNDING ANZOD Registry is funded by Commonwealth Department of Health and Ageing Kidney Health Australia New Zealand Ministry of Health COORDINATING CENTRE ANZDATA Registry and ANZOD Registry, C/- The Queen Elizabeth Hospital, 28 Woodville Road, Woodville, Adelaide, South Australia, 5011. Ms Penny Wride Prof G.R. Russ Dr S.P. McDonald Mrs L.R. Excell Mr B. Livingston Mrs E.K. Steinmetz Editor / ATCA Delegate for ANZOD Editor / Chair, ANZDATA Fellow in Epidemiology, ANZDATA Editor / Registry Manager ANZDATA Computer Programmer ANZDATA Administrative Officer ANZDATA Phone (61-8) 8222.6704 Fax (61-8) 8222.6402 Email anzdata@anzdata.org.au Web http://www.anzdata.org.au SUGGESTED CITATION The suggested citation for this report is as follows: ANZOD Registry Report 2005 Australia and New Zealand Organ Donation Registry Adelaide, South Australia. Editors: Leonie Excell, Graeme Russ, Penny Wride Publications based upon ANZOD Registry information reported here or supplied upon request, must include the citation as noted above and the following notice: The data reported here have been supplied by the Australia and New Zealand Organ Donation Registry. The interpretation and reporting of these data are the responsibility of the Authors and in no way should be seen as an official policy or interpretation of the Australia and New Zealand Organ Donation Registry. STATISTICAL METHODS Actuarial and Kaplan-Meier survivals have been produced using the procedure contained in SPSS for Windows Release 9.0.1 SPSS Inc. Printed in Adelaide, South Australia Copyright 2005 by the ANZOD Registry ISSN 1329-2889 ACKNOWLEDGMENTS The Editors would like to thank the Donor and Recipient Coordinators whose reporting of data has made this 2005 Report possible.

QUEENSLAND Tina Coco (Cooper) Alana Cresswell Aimee Cunningham Angela McInnes Francesca Rourke HEART AND LUNG TRANSPLANT UNIT Prince Charles Hospital, Rode Road, Chermside 4032 LIVER TRANSPLANT UNITS Princess Alexandra Hospital, Ipswich Road, Woolloongabba 4102 Royal Children s Hospital, Bowen Bridge Road, Herston 4029 RENAL TRANSPLANT UNIT Princess Alexandra Hospital, Ipswich Road, Woolloongabba 4102 NEW SOUTH WALES Carrie Alvaro Debbie Fleischer Adrian Sheridan HEART AND LUNG TRANSPLANT UNIT St Vincent s Hospital, Victoria Street, Darlinghurst 2010 AUSTRALIAN NATIONAL LIVER TRANSPLANT UNIT The Children s Hospital at Westmead, Hawkesbury Road, Westmead 2145 Royal Prince Alfred Hospital, Missenden Road, Camperdown 2050 NATIONAL PANCREAS TRANSPLANT UNIT Dept. Renal Medicine, Westmead Hospital, Cnr Hawkesbury and Darcy Road, Westmead 2145 The Children s Hospital at Westmead, Hainsworth Street, Westmead 2145 John Hunter Hospital, Lookout Road, New Lambton Heights, Newcastle 2305 Prince of Wales Hospital, Barker Street, Randwick 2031 (Sydney Children s Hospital, High Street, Randwick 2031) Royal North Shore Hospital, Pacific Highway, St Leonards 2065 Statewide Renal Services (Royal Prince Alfred Hospital), Missenden Road, Camperdown 2050 St George Hospital, Montgomery Street, Kogarah 2217 St Vincent s Hospital, Victoria Street, Darlinghurst 2010 Westmead Hospital, Cnr Hawkesbury and Darcy Road, Westmead 2145 ACT (AUSTRALIAN CAPITAL TERRITORY) Erika Gorecki Holly Northam

VICTORIA Samantha Brean Bernie Dwyer Nina Klein Violet Marion Kim O Sullivan Claire Wensor HEART AND LUNG TRANSPLANT UNITS Royal Children s Hospital, Flemington Road, Parkville 3052 The Alfred Hospital, Commercial Road, Prahran 3181 LIVER TRANSPLANT UNITS Austin Hospital, Austin Health,145 Studley Road, Heidelberg 3084 Royal Children s Hospital, Flemington Road, Parkville 3052 PANCREAS TRANSPLANT UNIT Monash Medical Centre, 246 Clayton Road, Clayton 3168 Alfred Hospital, Commercial Road, Prahran 3181 Austin Hospital, Austin Health, 145 Studley Road, Heidelberg 3084 Monash Medical Centre (Paediatric & Adult), 246 Clayton Road, Clayton 3168 Royal Children s Hospital, Flemington Road, Parkville 3052 The Royal Melbourne Hospital, Grattan Street, Parkville 3052 St Vincent s Hospital, 41 Victoria Parade, Fitzroy 3065 SOUTH AUSTRALIA AND NORTHERN TERRITORY Catherine Hannan Kathy Hee Raelene Kelly Helen Stewart (NT) Lee Wood (NT) Penny Wride SOUTH AUSTRALIAN LIVER TRANSPLANT UNIT Flinders Medical Centre, Flinders Drive, Bedford Park 5042 The Queen Elizabeth Hospital, 28 Woodville Road, Woodville 5011 Women s and Children s Hospital, 72 King William Road, North Adelaide 5006

WESTERN AUSTRALIA Karyn Boxshall Suzanne Foot Mary Lynch Denyse Norman Melissa Smith Daniel Winters HEART TRANSPLANT UNIT Royal Perth Hospital, Wellington Street, Perth 6001 LUNG TRANSPLANT UNIT Royal Perth Hospital, Wellington Street, Perth 6001 WA LIVER TRANSPLANTATION SERVICE Sir Charles Gairdner Hospital, Verdun Street, Nedlands WA 6009 Princess Margaret Hospital for Children, Roberts Road, Subiaco 6008 Royal Perth Hospital, Wellington Street, Perth 6001 Sir Charles Gairdner Hospital, Verdun Street, Nedlands 6009 NEW ZEALAND Dawn Kelly Janice Langlands HEART & LUNG TRANSPLANT SERVICE Auckland City Hospital, Grafton Road, Auckland LIVER TRANSPLANT UNIT Auckland City Hospital,Grafton Road, Auckland PANCREAS TRANSPLANT UNIT Auckland City Hospital, Grafton Road, Auckland Auckland City Hospital, Grafton Road, Auckland (Starship Children s Hospital, Auckland) Christchurch Hospital, Riccarton Avenue, Christchurch Wellington Hospital, Riddiford Street, Newtown, Wellington

TABLE OF CONTENTS INTRODUCTION SUMMARY Page Australia......... 1 New Zealand......... 1 ORGAN DONORS IN AUSTRALIA AND NEW ZEALAND Number and Donors per Million of Population.... 2 International Donor Statistics....... 2 Donors per Thousand Deaths....... 3 Australian States. Comparison between donors per million population and donors per thousand deaths..... 3 Number of Cadaveric Donors and Solid Organ Transplants and Patients on the Waiting List...... 3 DONOR POSTCODES......... 4 DONOR PROFILE IN AUSTRALIA AND NEW ZEALAND..... 4 Age and Gender Distribution....... 5 CAUSE OF DONOR DEATH........ 7 Donor Occupation, Ethnic Origin and Religious Denomination.. 10 INTENDED DONORS........ 11 NON HEART-BEATING DONORS....... 12 CARDIOPULMONARY RESUSCITATION...... 12 VIROLOGY SCREENING Cytomegalovirus Status of Donors...... 13 Epstein-Barr Virus Status of Donors...... 13 Hepatitis B and Hepatitis C Status of Donors.... 13 MEDICAL CONDITION OF DONORS....... 14 DONOR WEIGHT......... 15 BLOOD GROUP OF DONORS........ 15 DONOR INTENTION Driver s Licence and Donor Card Status..... 16 Australian Organ Donor Registry...... 16 AUTHORITY SOUGHT FOR ORGAN DONATION...... 17 DIRECT CONTACT WITH DONOR COORDINATOR..... 17 CORONER S CASES......... 18 SUMMARY OF ORGANS REQUESTED, CONSENT GIVEN, RETRIEVED AND TRANSPLANTED 18 ORGANS REQUESTED......... 19 MULTIPLE ORGAN RETRIEVAL....... 19 ORGAN RECIPIENTS TRANSPLANTED....... 20 Waiting List......... 20 EXCHANGE OF ORGANS Exchange of Organs between States and New Zealand.... 21 Summary of Organs Transplanted in Australia from New Zealand Donors. 21 KIDNEY DONATION Waiting List versus Cadaver Transplants..... 22 Outcome of Request for Kidney Donation..... 22 Age of Donors Providing Transplanted Kidneys..... 23 Cadaver Kidney Transplants - Australia and New Zealand... 23 Kidney Perfusion Methods....... 24 Reasons Kidneys were Unusable...... 25 Donor Age of Unusable Kidneys...... 25 Donor Kidney Function - Terminal Levels of Serum Creatinine and Urea. 26 Kidney Transplant Outcome....... 27 LIVER DONATION Waiting List versus Cadaver Transplants..... 28 Outcome of Request for Liver Donation..... 28 Age of Donors Providing Transplanted Livers..... 29 Liver Transplants by Transplant State and Country.... 29 Perfusion of Livers........ 29 Regional Outcome of Requests for Liver Donation... 30 Reasons Livers were Unusable after Retrieval..... 30 Donor Age of Unusable Livers....... 30 Donor Liver Function........ 31 Liver Transplant Outcome....... 31 CARDIOTHORACIC ORGAN DONATION Waiting List versus Cadaver Transplants..... 32 Outcome of Request for Heart Donation..... 33 Age of Donors Providing Transplanted Hearts..... 33

TABLE OF CONTENTS Heart Transplants by State and Country..... 34 Heart and Lung Transplant Recipients by Country.... 34 Regional Outcome of Requests for Heart Donation... 34 Heart Valve Donation........ 35 Age of Heart Valve Donors....... 35 Regional Outcome of Requests for Heart Valve Donation... 35 Outcome of Request for Lung Donation..... 36 Age of Donors Providing Transplanted Lungs..... 36 Lung Transplant Recipients....... 37 Regional Outcome of Requests for Lung Donation... 37 Donor Lung Function........ 37 CARDIOTHORACIC SPECIAL SECTION Contributed by Associate Professor Anne Keogh and Mr Ross Pettersson 38 PANCREAS DONATION Waiting List versus Cadaver Transplant.... 42 Outcome of Request for Pancreas Donation..... 42 Age of Donors Providing Transplanted Pancreas.... 43 Regional Outcome of Requests for Pancreas Donation.... 43 CORNEAL DONATION Outcome of Request for Cornea Donation..... 44 Age of Corneal Donors........ 44 Regional Outcome of Requests for Corneal Donation..... 44 BONE DONATION Outcome of Request for Bone Donation..... 45 Age of Bone Donors........ 45 Regional Outcome of Bone Donation...... 45 TERMINAL MANAGEMENT Time from Admission to Brain Death...... 46 Time from Ventilation to Brain Death...... 47 Time from Brain Death to Aortic Cross Clamp..... 47 DONOR MAINTENANCE........ 48 TERMINAL TREATMENT........ 49 APPENDIX I AUSTRALIA Yellow Pages Donor Numbers for each State, Gender Numbers and Age Groups for each State.. 4 Number of Donors from each Hospital...... 6 Cause of Donor Death Related to Gender and Age Group.... 9 Cause of Donor Death in each State and Australia..... 12 Organs Requested by Donor State....... 14 Organ Consent Obtained by Donor State...... 15 Organ Consents by Donor State and Australia....... 16 Reason Organs not Requested by Donor State...... 17 Organs Retrieved by Donor State....... 20 Solid Organs Retrieved by Donor State and Australia...... 22 Reason Organs not Retrieved by Donor State...... 23 Organs Retrieved in Each Donor State by Retrieval State Team.... 28 Donor Age Related to Transplanted Organs...... 30 Outcome of Organs Retrieved in Australia...... 32 Transplanted Solid Organs by Transplanting State - Donated from Australia or New Zealand 37 Transplanted Solid Organs in Australia - Donated from Australia or New Zealand.. 37 Transplanted Solid Organs from Donor Australian State - Transplanted in Aust. or NZ. 38 Transplanted Solid Organs from Donor Australian State - Transplanted in Aust. or NZ. 39 Transplanted Solid Organs Donated from Australia - Transplanted in Aust. or NZ.. 39 Transplanted Solid Organs from Donor States - Australian Donors... 40 Transplanted Solid Organs - Donor State to Destination State.... 42 Population by Age - Australian States and Territories..... 46 APPENDIX II NEW ZEALAND Green Pages Donor Gender Numbers and Age Groups...... 3 Number of Donors from Each Hospital...... 3 Cause of Donor Death Related to Gender and Age Group.... 4 Reason Organs not Requested....... 5 Organ Consents......... 6 Solid Organs Retrieved........ 7 Organs Retrieved in New Zealand by Retrieval State Team.... 8 Reason Organs not Retrieved........ 9 Outcome of Organs Retrieved in New Zealand..... 11 Donor Age Related to Transplanted Organs - Retrieved in New Zealand.. 12 Transplanted Solid Organs - Donor State to Destination State.... 14 Transplanted Solid Organs - Donated from New Zealand or Australia... 18 Estimated Resident Population by Age Groups..... 18

INTRODUCTION We are pleased to present the 2005 Report of the Australia and New Zealand Organ Donation Registry (ANZOD Registry). This report contains 2004 data as well as cumulative Australian data from the inception of the Registry in 1989 and New Zealand data since 1993. The Registry is a collaborative effort of the Australasian Transplant Coordinators Association (ATCA Inc) and the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA). The Registry is grateful for the ongoing financial support provided through the Commonwealth Department of Health and Ageing, Kidney Health Australia and the New Zealand Ministry of Health. The staff employed by the ANZOD Registry are exceptionally dedicated and take great pride in their work. Mrs Lee Excell continues her meticulous work as the Registry and Database Manager, Mrs Lis Steinmetz is responsible for the layout and presentation of the report, and Mr Brian Livingston provides statistical programming and expertise. This year Ms Penny Wride has contributed to the editorial process. The report can be accessed via our Internet Web Site http://www.anzdata.org.au. Graeme Russ