Translating Colorectal Cancer Research Workshop & EuCOLONGENE/COST Action BM1206 meeting

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Translating Colorectal Cancer Research Workshop & EuCOLONGENE/COST Action BM1206 meeting 8-10 February 2017, IPO-Porto, Porto, Portugal Useful Information 1. How to get to Porto Page 2 2. Recommended hotels Page 3 3. Meeting venue Page 5 4. Social program Page 8 5. Walking history Page 10

1. How to get to Porto Arriving in Porto Porto is served by the Francisco Sá Carneiro International Airport (OPO), which is located about 11 km (7 miles) north of the city center. The airport is used by many of the major regular airlines, as well as low cost airlines. In case you arrive through Lisbon Airport (which is more than 300 km from Porto), you can either get a 45 min connection flight to Porto with TAP Portugal (www.flytap.com) or the low-cost Ryanair (www.ryanair.com), or you can catch a fast train (train AP) that departs every 1-2 hours and takes about 2h45m (www.cp.pt/passageiros/en/). To reach the train station, just take the metro from Lisbon airport to train station Lisboa- at Porto-Campanhã train Oriente. The train to Porto stops station, where you can catch the Metro to Trindade station. Additional information about the Porto airport can be found here: http://www.ana.pt/en-us/aeroportos/porto/porto/theairport/abouttheairport Passengers with reduced mobility can find specific information here: http://www.ana.pt/en-us/aeroportos/porto/porto/arrivals/mobilidadereduzida/pages/reduced-mobility.aspx Travelling from Porto airport to the city The Metro of Porto (mixed surface and underground system) operates five different lines labeled from A to E and these lines are differentiated using colors. Porto Airport is served by Line E (violet). The airport stop is located near the terminal and the Metro departs every 20 min. The trip to the city center takes 26 minutes. You can buy the rechargeable ticket (Andante) at the automatic ticket machine at the station (Z4 ticket 1.85 + 0.60 the first time you buy the Andante rechargeable ticket). Leave in Trindade to change to line D (yellow) to go to the meeting venue or nearby hotels (line D towards Hospital São João, stop IPO station) or to go to the main city square nearby most other recommended hotels (line D towards Santo Ovídio, stop Aliados station, just one stop from Trindade). If you change Metro line you can use the same ticket within 1 hour, but you must validate it every time before entering the Metro. See maps below. More information and a journey planner can be found here: http://www.metrodoporto.pt/en/ In case you prefer, taxi services are available outside of the arrivals hall of the airport. Travelling from the airport to the city center by taxi takes 20 to 30 mins and costs 20/25. 2

2. Recommended hotels Website: http:// /www.eurostarsoporto.com/en/hotel.html E-mail: recepcion@eurostarsoporto.com Price: 54 (http://www.eurostarsoporto.com/es/hotel.html?id_referer=uniporto; Promotion code: UNIPORTO) Notes: New hotel within walking distance to the meeting venue Google Maps: https://goo.gl/maps/rq18k Website: http:/ //www.accorhotels.com/gb/hotel-3227-ibis-porto-sao- joao/index.shtml E-mail: H3227@accor.com Price: 47 Notes: new budget hotel within walking distance to the meeting venue. Access to IPO-Porto taking the lift to the shopping gallery (street level) and turn left to reach the closest exit to the meeting venue Google Maps: https://goo.gl/maps/m13et Website: http:/ //www.grandehotelporto.com/en/ E-mail: reservas@grandehotelporto.com Price: 48 Notes: Localized in city center, within walking distance to metro (Aliados station on line D, 11 min. ride to IPO station) Google Maps: https://goo.gl/maps/udtgx Website: http:/ //www.hotelmoov.com/ E-mail: porto@ @hotelmoov.com Price: 56,50 Notes: Localized in city center, within walking distance to metro (Aliados station on line D, 11 min. ride to IPO station) Google Maps: https://goo.gl/maps/9jfwr 3

Website: http://www.hotelparis.pt/eng/ E-mail: hotel@hotelparis.pt Price: 53 (https://bookings.hotelparis.pt; Promotion code COST-BM1206) Notes: Localized in city center, within walking distance to metro (Aliados station on line D, 11 min. ride to IPO station) Google Maps: https://goo.gl/maps/cas6e Indicated prices are for single room per night including breakfast. Prices and room availability may vary somewhat depending how long in advance you make the reservation. When indicated use the promotion code. For hotel localization in relation to the meeting venue and Metro stations see the maps on pages 6 and 7. Other hotels: http://www.tripadvisor.com/hotels-g189180-porto_porto_district_northern_portugal-hotels.html 4

3. Meeting venue Meeting venue location The meeting venue will be at the Portuguese Oncology Institute of Porto (IPO-Porto), located in Rua Dr. António Bernardino de Almeida, 4200-072 Porto (Google Maps: https://goo.gl/maps/86enq) ). IPO-Porto is the largest specialized Portuguese cancer institution with a triple role: patient care, research and teaching in Oncology (www.ipoporto.pt/en/). It is a member of the Organization of European Cancer Institutes (OECI) and it treats about 10.000 new patients per year. The meeting venue in IPO-Porto will take place at the facilities of EPOP (Escola Portuguesa de Oncologia do Porto), namely at the main auditorium and adjacent meeting rooms. Arriving at the meeting venue The hotels Eurostars Oporto and Ibis Porto S. João are within walking distance to the meeting venue (see map next page). Just find the IPO-Porto entrance just opposite the Metro IPO station and walk straight ahead inside IPO-Porto limits in direction of the building with a banner indicating EPOP - Escola Portuguesa de Oncologia do Porto. The other recommended hotels in the city center are nearby the Aliados Metro station (see map on page 7), which is 11 min. away from the meeting venue. Take the Metro line D (yellow) at Aliados station towards Hospital São João until the IPO station, which is just opposite the IPO-Porto entrance that allows direct access to the meeting venue (see above). Entrance to the meeting venue (go straight ahead, stairs to the right, lift to the left, venue is one floor up in the 3 rd floor 5

Meeting venue Local transport The rechargeable ticket Andante can be bought at the automatic ticket machines at any Metro station and can be used both in the Metro and buses (STCP). To travel by Metro between the city center and the meeting venue (Metro every 6 min.) you need a Z2 ticket (1.20 + 0.60 the first time you buy the Andante rechargeable ticket). Validate your ticket before entering the Metro and inside the bus and every time you change lines. For further maps and schedules see the links below: Metro: http://www.metrodoporto.pt/en/ Busses: http://www.stcp.pt/en/travel/maps/search-maps/ 6

Meeting rooms The major sessions will take place in the main auditorium and smaller meeting rooms are available if necessary. Lunch and coffee-breaks Lunch and coffee-breaks will be served on site in the facilities adjacent to the meeting venue. Internet access Wireless internet access is available at the meeting venue at no cost. If you have an eduroam connection at your home institution, you will be able to access the internet using the same login at the meeting venue by using the eduroam network access. If not, you will be able to access the internet via the WiFi Porto Digital network, which is also available free of charge in several hotspots in the city and in local busses. 7

4. Social program COST Action BM1206 dinner The COST Action BM1206 dinner will take place on February 8th, 8PM, at Adega & Presuntaria Transmontana II restaurant. Located at Gaia riverside, the stone walls of the Adega & Presuntaria Transmontana II hark back to medieval times. Location: Avenida Diogoo Leite 80, 4400-111 Vila Nova de Gaia (map on page 9). This restaurant has a magnificent view over the city of Porto, but its main attraction is the traditional Portuguese cuisine focusing on Trás- os-montes (north of Portugal) products. The menu here is nothing short of amazing and I can assure you that your appetite will be put to the test. Advise: make sure you reserve some space for the delicious desserts (https://www.facebook.com/pages/adega-e-presuntaria-transmontana-ii/270129973070387). Workshop dinner The Workshop dinner (for COST Action BM1206 members and invited speakers) will take place on February 9th, 8PM, at Cálen Port wine celar, located in the riverside of Vila Nova de Gaia close to D Luiz I bridge. It enjoys a spectacular location with magnificent views across the Douro River to the old historic center of Porto. Location: Avenida Diogo Leite, 344, 4400-111 Vila Nova de Gaia (map on page 9). Before the dinner, we will have a visit to the Cálem Port wine cellar (http://www.calem.pt/). During the tour the visitor will be given the opportunity to learn about the fascinating history of Port wine, the unique characteristics of each type of Port Wine, and be guided through our cellars where wines age in protected light and air conditions. 8

Other restaurants recommendedd for dinner For those staying at hotels near the meeting venue, there are several small restaurants in the area nearby the Eurostars Oporto hotel. Furthermore, the Ibis hotel is situated in a building with a shopping galleria (Campus S. João) with a food court with several options for light meals. Otherwise, there are plenty of good restaurant options in the area around the hotels in the city center, as well as at the waterfront (Ribeira) on both sides of the river. 9

5. Walking history (create your own guide here: http://www..visitporto.travel/) The history of Porto dates back to the 4th century, to the Roman occupation of the Iberian Peninsula. Portus Cale, later referred to as Portucale, was the origin for the modern name of Portugal, which became independent in 1139 (recognized in 1143). Situated on the right bank of the River Douro, very close to its mouth, the city of Porto has a historical center that still preserves a strong identity forged over many centuries and clearly visible in its remarkable buildings and unique urban fabric enlivened by the great vitality of the local inhabitants. Strategically close to the Atlantic coast, at a natural intersection of the routes travelled by people from both North and South, the city has always played an important role in international trade. Furthermore, not only did it escape the great waves of destruction that swept through so many other cities, but it is also fortunate enough to enjoy a geographical setting of exceptional beauty. These were surely the reasons why UNESCO was to include Porto in its World Heritage list in 1996. This classification also extends to the left bank, taking in the Ponte de D. Luis, the city's emblematic iron bridge, built by a disciple of the famous Eiffel, the Mosteiro da Serra do Pilar and the wine lodges that line the river bank in Gaia, where that great ambassador of the city's name, Port wine, is left to age before being sent to all corners of the world, bringing great pleasure to all those who drink it. You should therefore begin your visit on this bank, for you will understand the city better once you have enjoyed this wonderful view of it climbing up the hills opposite. First of all, however, you should take the opportunity to sample the famous Port wine and listen to its story being told. It is also well worth your trouble to climb up to the Mosteiro da Serra do Pilar, from where you will gain an even more splendid view of the bend in the river, the bridge and the city. You should also visit the monastery, a Renaissance church that has the special peculiarity of a round cloister. Returning to the right bank, begin your tour at the cathedral, which was built in the twelfth century, in the time of D. Hugo, the city's first bishop, who also supervised the building of the first defensive walls. The great age of the cathedral can be seen in the bell towers, which give the building its appearance of a fortress church. The powerful looking buttresses on the main facade stand either side of the original Romanesque rose window and the eighteenth century doorway. Also visible on the outside is a baroque loggia attributed to Nicolau Nasoni, which epresents a later addition to the north face. Inside, the visitor's attention is drawn to the baroque chancel, with its magnificent altarpiece, and the altar of the Chapel of the Holy Sacrament, a most valuable work of' art from the seventeenth and eighteenth centuries, made by local silversmiths. At the south end of the cathedral is the elegant Gothic cloister, with its beautiful eighteenth century azulejos. This group of buildings includes the magnificent Episcopal Palace, also from the twelfth century, whose size reflects the early ecclesiastical dominance of the city that would later be curbed by the Crown's interests and the city's determination. The palace's present day external appearance is the result of its remodeling in eighteenth century, possibly under the supervision of Nicolau Nasoni. Slightly below the cathedral square is the church and convent of Grilos, built in the sixteenth century, with its impressive mannerist front. In the area around the cathedral (crossing over Avenida de Vimara Peres) and close to the Igreja de Santa Clara are some stretches of the city's old Fernandine Wall. This was the second ring of defensive walls, with a perimeter of roughly 3,400 metres, completed in the reign of D. Fernando in the fourteenth century. 10

You should visit the church, which dates back to the fifteenth century, and admire its Renaissance doorway and remarkable interior, its walls lined with finely carved and gilded woodwork, one of the most typical features of Portuguese decorative art. Returning to Rua de D. Hugo, take some time to admire the attractive mansions emblazoned with their owners coats of arms, particularly the Casa-Museu Guerra Junqueiro, which houses the valuable collection of decorative art put together by this local poet and writer. Next to number 5 in this street, notice the only remaining visible section of the first medieval wall. At the end of the Middle Ages, Porto was a city with a thriving commercial activity, mostly carried out near the port and at the administrative facilities that can still be seen today on the quayside of Cais da Ribeira and in the customs house of the Casa do Infante. Other buildings and houses appeared as a result of this cosmopolitan activity, all of which were protected by the Fernandine wall. Between Rua da Fonte Taurina and Cais da Estiva, you can still see the opening in the wall made for the storage of coal, the only one that is now left. In order to reach this area, you will have to walk down from the cathedral towards the river, passing through the popular Barredo quarter, down its steep, narrow streets and alleys. In the riverside area close to Cais da Ribeira, you will find a number of pavement cafes inviting you to pause for a while before continuing on to Largo do Terreiro and then into Rua da Alfandega. Here, on the right, is a typical sixteenth century house, which acted as the first royal customs house. Above the entrance, a stone inscribed with the date I894 testifies to the birth here of Prince Henry the Navigator five hundred years before. Thereafter the building took the name of the Casa do Infante (the Prince's House), although it is most likely that the son of D. Joao I was born in the palace that his father had built in the area, and which has since been demolished. A little further up the hill is Rua do Infante Dom Henrique (formerly known as Rua dos Ingleses), where the impressive building known as the Feitoria Inglesa (the English Factory House) is to be found. This same street leads into the square of the same name, which has a nineteenth century metal construction in the center, Mercado Ferreira Borges, which used to be the city's main supply market, as well as a modest monument built as a memorial to Prince Henry. The neoclassical Palácio da Bolsa, commissioned in 1842 by the Porto traders to act as the city's stock exchange, is the dominant feature in this square. The great opulence of the different materials used to decorate the building's interior reveals an eclecticism that is unique in Portugal and reflects the important role played by commerce in the life of the city in the nineteenth century. Amongst its many interesting rooms, the most famous is undoubtedly the Arab Room, romantically inspired by the Alhambra palace in Granada. Side by side with the Palácio da Bolsa stands the lgreja de São Francisco. Although this was originally a Gothic church, it has become one of the city's most important baroque works. Above the main entrance on the west facade, attention is drawn to the various features added over different periods: its original beautiful rose window, symbolizing the wheel of fortune, is situated above the Renaissance doorway, itself flanked by baroque columns. Inside the church, the earlier Franciscan austerity has been completely superseded by the ostentatiousness of the 370 kg of gold that cover the baroque carved woodwork. Particularly impressive here is the altar with its famous ''Tree of Jesse''. Turning now towards the mouth of the river, you can see the colorful and picturesque houses of Miragaia and, on the left, by the river bank, the imposing Customs House standing on an artificial platform, built on the site of a former beach and a remarkable example of nineteenth century engineering. 11

Returning once more to the lgreja de São Francisco, you should carry on to Largo de São João Novo, where the church with the same name is to be found, its severe but beautiful facade surmounted by two bell towers. From this square, you should set off down Rua de Belmonte (which previously marked the limits of the Jewish quarter), with its typical sixteenth and seventeenth century houses, whilst in the other direction is Rua das Taipas, whose most notable feature is a row of seven houses standing on carved granite consoles. In Rua das Virtudes, next to an old manor house is a terrace built on one of the towers of the old Fernandine wall. Rua dos Clérigos leads to Praça da Liberdade, the city's main square in which there is a statue of D. Pedro IV on horseback, the liberal king who gave his heart to the city of Porto. The square extends into the Avenida dos Aliados, with the Town Hall at the top, giving the city a decidedly Nordic flavor. A little further below Praça da Liberdade is the São Bento railway station, which adds yet another contrast, this time one of French inspiration. The walls of the spacious entrance all are covered with decorative azulejos depicting important events in the history of Portugal, as well as scenes of everyday life based on motifs drawn from agriculture, commerce and local customs. From here, you should make your way down Rua das Flores, which begins across the road from the station. It was built in 1521 at the orders of the king D. Manuel I, the ground floor of the street being full of goldsmiths, jewelers and shopkeepers, who lived in the floors above their shops. It still preserves the delightfull atmosphere of a bourgeois shopping area, reflected in the azulejos of the buildings, the beautiful designs the wrought iron balconies and the decorative ornaments framing the names of the shops. Squeezed into the middle of this bourgeois atmosphere is the baroque lgreja da Misericórdia, with its imposing facade by Nicolau Nasoni. Returning to the São Bento railway station, walk up the hill to Praça da Batalha, where the most prominent buildings are the São João theatre and a manor house, which once housed the central post office. This marks the outer limit of the classified area. The charms of this city are not limited to the area contained within its ancient walls. You must also make sure to enjoy a tram ride to the delightful Foz do Douro at the mouth of the river (http://www.stcp.pt/en/tourism/porto-tram-city- tour/) and nearby beaches, as well as to visit the modern Music House in Rotunda da Boavista (reached by Metro). But do not think that this is all. As if it has been overcome by a certain timidity, Porto is reluctant to reveal itself completely at first sight. You have to train yourself to look for the details, the contrasts, the sudden unexpected balconies overlooking the River Douro, learning how to appreciate its discreet light. Make sure that you go inside the shops, cafes and cake shops, for it is here that the warmth and friendliness of the people will show you yet another feature of the city s world heritage. Returning once again to Rua das Taipas, your attention is drawn to the solid sturdy structure of' the Cadeia da Relação, the former prison, which was rebuilt in the eighteenth century. Next to this is the lgreja de São Bento da Vitória, built on the site of an old sixteenth century synagogue. Inside the church, the chancel provides another highly decorative example of baroque carved and gilded woodwork. Passing through the Jardim da Cordoaria, enlivened by a series of sculptures by Portuguese artists, you will emerge in of the baroque lgreja and Torre dos Clérigos, built by Nicolau Nasoni. The elegant tower is 75m high and has become the landmark of the city of Porto. In the street directly opposite he church, it is worth paying a visit to the Lello bookshop, whose inside is lined with some quite remarkable carved woodwork. Text adapted from the Portuguese Tourist Office For more see: http://www.visitporto.travel/ 12